ASCP CG CERTIFICATION EXAMINATION TEST 2026 QUESTIONS WITH SOLUTIONS GRADED A+

ASCP CG CERTIFICATION EXAMINATION TEST
2026 QUESTIONS WITH SOLUTIONS GRADED
A+



◉ nuclear shrinkage and increased basophilia = Answe: pyknosis


◉ fragmented, pyknotic nucleus = Answe: karyorrhexis


◉ architecture is preserved in what necrosis? Answe: coagulative


◉ bacteria/fungus/inflammation/enzymes are part of what necrosis?
Answe: liquifactive


◉ WBC recruitment steps Answe: margination/rolling --> adhesion -->
transmigration --> migration


◉ WBC rolling via _____ Answe: selectins


◉ WBC adhesion via ____ Answe: integrins

,◉ Virchow's triad of thrombosis Answe: endothelial injury +
stasis/turbulent blood flow + hypercoagulability


◉ most abundant collagen Answe: type I


◉ collagen in scar tissue, tendons, ligaments Answe: type I


◉ collagen in cartilage Answe: type II


◉ reticular collagen type Answe: type III


◉ BM collagen type Answe: type IV


◉ what does vWF do? Answe: helps platelets adhere to endothelium


◉ FBN1 mutation = what disorder Answe: Marfan syndrome


◉ fibrillin mutation = what disorder Answe: Marfan syndrome


◉ mutated collagen = what disorder Answe: Ehlers-Danlos


◉ musty urine odor = what disorder Answe: PKU

,◉ mutated beta-hexosaminidase A = what disorder Answe: Tay Sachs


◉ increased gangliosides = what disorder Answe: Tay Sachs


◉ mutated sphingomyelinase/increased sphingomyelin = what disorder
Answe: Neimann Pick


◉ mutated glucocerebrosidase/increased glucocerebroside = what
disorder Answe: Gaucher


◉ trisomy 13 aka Answe: Patau


◉ Patau = Answe: trisomy 13


◉ trisomy 18 aka Answe: Edwards'


◉ Edwards' = Answe: trisomy 18


◉ 3 viable trisomies Answe: 13, 18, 21


◉ maternal imprinting Answe: silencing of maternal allele

, ◉ paternal imprinting Answe: silencing of paternal allele


◉ #1 infant tumor Answe: hemangioma


◉ #1 extracranial child tumor Answe: neuroblastoma


◉ PDK1 mutation = what disorder Answe: adult PKD


◉ polycystin-1 defect = what disorder Answe: adult PKD


◉ PKHD1 mutation = what disorder Answe: childhood PKD


◉ fibrocystin defect = what disorder Answe: childhood PKD


◉ MHS2/MLH1 mutation = what disorder Answe: HNPCC/Lynch


◉ most common newborn viral infection Answe: CMV


◉ Hyaline membrane disease Answe: defective surfactant --> solid,
airless lungs in infant