NURS 5334 ANTIMICROBIALS EXAM QUESTIONS AND ANSWERS LATEST DOWNLOADED 2025/2026 A COMPLETE SOLUTION ALL ANSWERS 100% ACCURATE BEST GRADED A+ FOR SUCCESS

NURS 5334 ANTIMICROBIALS EXAM QUESTIONS AND ANSWERS
LATEST DOWNLOADED 2025/2026 A COMPLETE SOLUTION ALL
ANSWERS 100% ACCURATE BEST GRADED A+ FOR SUCCESS

Cephalosporins - CORRECT ANSWERS -Structurally and functionally similar to penicillins
-Not 1st line for brain infections d/t not adequately crossing CSF.
-dose reduction in renal
-1st gen. drugs have highest chance of PCN reaction.


Cephalosporins - CORRECT ANSWERS Ineffective against listeria, C.diff, enterococcus.


First generation cephalosporins - CORRECT ANSWERS proteus mirabilis, E. coli,
Klebsiella pneumoniae, oral cavity anaerobes.
Bacteroides fragilis is resistant to these drugs.
-cephalexin, cefadroxil, cefazolin, cephradine


Second generation Cephalosporins - CORRECT ANSWERS H. flu, klebsiella spp, proteus
spp, E. coli, M catarrhalis, Bacteroides fragilis.
- cefaclor, cefotetan, cefoxitin, cefprozil, cefuroxime


Third generation cephalosporins - CORRECT ANSWERS Can cause C. diff.
b-lactamase producing H. influenza, Neisseria gonorrhea, Serratia marcescens Providencia spp.
-cefotaxime, ceftriaxone, ceftazidime (pseudomonas aeruginosa), cefixime, cefdinit,
cefpodoxime, ceftibuten


Ceftriazone & Cefotaxime - CORRECT ANSWERS Third gen cephalosporin- DOC in
meningitis, no dose reduction in CKD


Carbapenems - CORRECT ANSWERS b-lactam abx, penetrate well into CSF when
meninges are inflamed. Reduce in CKD.
-imipenem (empiric), meropenem (brain infections), doripenem, ertapenem

,NURS 5334 ANTIMICROBIALS EXAM QUESTIONS AND ANSWERS
LATEST DOWNLOADED 2025/2026 A COMPLETE SOLUTION ALL
ANSWERS 100% ACCURATE BEST GRADED A+ FOR SUCCESS


B-lactamase Inhibitors - CORRECT ANSWERS combine with PCN for abx effect.
-clavulanic acid, sublbactam, tazobactam


carbapenem + B-lactamase inhibitors drugs - CORRECT ANSWERS approved for treating
complicated UTI with pyelonephritis
-meropenem (carba) + vaborbactam (BLI)


cephalosporin + B-lactamase inhibitor - CORRECT ANSWERS used to treat intra-
abdominal infections (use with metronidazole (Flagyl)) and complicated UTI


Vancomycin- tricyclic bactericidal - CORRECT ANSWERS aerobic and anaerobic gram +,
MRSA, MRSE, enterococcus, C. diff (oral)
skin and soft tissue infections, infective endocarditis, nosocomial pneumonia
- monitor CrCl
-ADE nephro/ototoxicity


lipoglycopeptides - CORRECT ANSWERS concentration-dependent, gram +
-telavancin- acute bacterial skin infections- fetal harm, nephrotoxic
-reactions can occur with blood thinners
-oritavancin
-dalbavancin
-daptomycin- MRSE< VRE, right sided infective endocarditis, SSI, cannot treat pneumonia
-fosfomycin- 1st line for acute cystitis. One time dosing.

, NURS 5334 ANTIMICROBIALS EXAM QUESTIONS AND ANSWERS
LATEST DOWNLOADED 2025/2026 A COMPLETE SOLUTION ALL
ANSWERS 100% ACCURATE BEST GRADED A+ FOR SUCCESS

Protein synthesis inhibitors - CORRECT ANSWERS inhibit bacterial protein synthesis-
bacteriostatic
- quinolones
-folic acid antagonists
- urinary tract antiseptics


Tetracycline - CORRECT ANSWERS teratogenic*
-DOC for chlamydia
-decreased absorption if given with magnesium, calcium, aluminum, antacids, iron
-do not give to children bc it will bind with teeth/ bones.
-tetracycline- give on empty stomach
-doxycycline- used with acne
- minocycline- treat meningococcal carrier
-sarecycline- acne vulgaris (12wk), wt based, baseline eye exam


Glycylcyclines - CORRECT ANSWERS -Tigecycline- community aquired pneumonia
Broad spectrum; bacteriostatic
Bind to the 30S ribosomal subunit
Inhibits rapid efflux; administered intravenously
Useful against MRSA, multi-resistant strep, VRE, poor option for blood stream infections. Need
dose reduction with liver disease. Decreases clearance of Warfarin.


Aminoglycosides - CORRECT ANSWERS concentration-dependent bactericidal. renal
dosing required. give with b-lactam abx to get synergistic effect when treating enterococcus
faecalis.
-Amikacin