Final Exam: NR 546 / NR546 (Latest
Update ) Advanced
Pharmacology: Psychopharmacology
for the Psychiatric-Mental Health
Nurse Practitioner | Questions &
Verified Answers | 100% Correct |
Grade A - Chamberlain
Question:
pharmacologic treatment for bipolar disorder
Answer:
lithium, anticonvulsants, second gen antipsychotics
Question:
lithium
Answer:
used for euphoric mania, rapid cycling, or maintenance therapy
MOA: alters cation transport in the nerve and muscle
*1st line of treatment for new onset bipolar with acute mania
,Question:
lithium labs
Answer:
serum thyroid level, renal function, thyroid function
- can cause renal and thyroid tox
-monitor lithium levels 5 days after any dose adjustment
-monitor lithium levels regularly q6mo
starting dose should be decreased by 50% for pts with renal failure
-avoid in pregnancy and breast feeding
Question:
lamotrigine
Answer:
maintenance therapy or monotherapy for bipolar
MOA: affects sodium ion transport and enhances the activity of y-
aminobutyric acid (GABA)
- well tolerated but can cause a rash
- avoid in breast feeding
,Question:
valproic acid
Answer:
used for acute mania, mixed mood, multiple prior episodes, comorbid
substance abuse
MOA: affects ion transport and enhances the activity of GABA
-teratogenic avoid in pregnancy
Question:
valproic acid labs
Answer:
serum valproate level, liver fxn, cbc
-can cause thrombocytopenia, leukopenia, hepatotoxicity
-monitor labs q 3 mo for 1 yr ,then annually
, Question:
SGAs
Answer:
used in acute bipolar depression, acute mania or mixed episodes, or as bipolar
maintenance/adjunct
MOA: DA, NE, 5HT receptor antagonists
labs: cbc, HgB A1C
-can increase bs and cause DMII, blood dyscrasias
-labs q 3 mo for 1 yr, then annually
Question:
SGA drugs
Answer:
aripiprazole
cariprazine
lurasidone (take with food, safe for preg)
quetiapine
asenapine
risperidone
olanzapine
ziprazadone
Update ) Advanced
Pharmacology: Psychopharmacology
for the Psychiatric-Mental Health
Nurse Practitioner | Questions &
Verified Answers | 100% Correct |
Grade A - Chamberlain
Question:
pharmacologic treatment for bipolar disorder
Answer:
lithium, anticonvulsants, second gen antipsychotics
Question:
lithium
Answer:
used for euphoric mania, rapid cycling, or maintenance therapy
MOA: alters cation transport in the nerve and muscle
*1st line of treatment for new onset bipolar with acute mania
,Question:
lithium labs
Answer:
serum thyroid level, renal function, thyroid function
- can cause renal and thyroid tox
-monitor lithium levels 5 days after any dose adjustment
-monitor lithium levels regularly q6mo
starting dose should be decreased by 50% for pts with renal failure
-avoid in pregnancy and breast feeding
Question:
lamotrigine
Answer:
maintenance therapy or monotherapy for bipolar
MOA: affects sodium ion transport and enhances the activity of y-
aminobutyric acid (GABA)
- well tolerated but can cause a rash
- avoid in breast feeding
,Question:
valproic acid
Answer:
used for acute mania, mixed mood, multiple prior episodes, comorbid
substance abuse
MOA: affects ion transport and enhances the activity of GABA
-teratogenic avoid in pregnancy
Question:
valproic acid labs
Answer:
serum valproate level, liver fxn, cbc
-can cause thrombocytopenia, leukopenia, hepatotoxicity
-monitor labs q 3 mo for 1 yr ,then annually
, Question:
SGAs
Answer:
used in acute bipolar depression, acute mania or mixed episodes, or as bipolar
maintenance/adjunct
MOA: DA, NE, 5HT receptor antagonists
labs: cbc, HgB A1C
-can increase bs and cause DMII, blood dyscrasias
-labs q 3 mo for 1 yr, then annually
Question:
SGA drugs
Answer:
aripiprazole
cariprazine
lurasidone (take with food, safe for preg)
quetiapine
asenapine
risperidone
olanzapine
ziprazadone
