BSN 315 HESI Pharmacology V1 Exam (Exams –
2025/2026 Edition) | Nightingale College | Actual
Verified Questions and Answers
The 2025/2026 BSN 315 HESI Pharmacology V1 Exam package includes complete and
verified exam set aligned with the Nightingale College nursing curriculum. This set is carefully
structured to assess advanced pharmacological principles, medication administration, and safe
nursing practice.
Key Focus Areas:
Drug classifications and therapeutic uses, pharmacokinetics, dosage calculations, adverse
effects, contraindications, and clinical reasoning in patient medication management.
Answer Format
All correct answers are presented in bold and green with detailed rationales explaining the
underlying pharmacological concepts, ensuring accurate preparation for the BSN 315 HESI
Pharmacology V1 Exam (2025/2026).
Drug Classifications and Therapeutic Uses (10 Questions)
1. A patient is prescribed lisinopril for hypertension. What is the primary
therapeutic effect?
a) Increases blood pressure
b) Reduces blood pressure by inhibiting ACE
c) Increases heart rate
d) Promotes fluid retention
Answer: b) Reduces blood pressure by inhibiting ACE
Rationale: Lisinopril, an ACE inhibitor, reduces angiotensin II formation, leading to
vasodilation and decreased blood pressure.
2. What is the primary therapeutic use of metformin?
a) Treat bacterial infections
b) Manage type 2 diabetes mellitus
c) Prevent seizures
d) Reduce inflammation
Answer: b) Manage type 2 diabetes mellitus
Rationale: Metformin decreases hepatic glucose production and improves insulin sensitivity,
making it a first-line treatment for type 2 diabetes.
3. A patient is prescribed warfarin for atrial fibrillation. What is the primary
therapeutic effect?
a) Increases clotting
, b) Prevents clot formation
c) Increases heart rate
d) Reduces blood pressure
Answer: b) Prevents clot formation
Rationale: Warfarin inhibits vitamin K-dependent clotting factors, reducing thrombus
formation.
4. What is the primary therapeutic use of albuterol?
a) Treat hypertension
b) Relieve bronchospasm in asthma/COPD
c) Reduce blood glucose
d) Prevent infections
Answer: b) Relieve bronchospasm in asthma/COPD
Rationale: Albuterol is a short-acting beta-2 agonist that bronchodilates, relieving respiratory
symptoms.
5. A patient is prescribed simvastatin for hyperlipidemia. What is the primary
therapeutic effect?
a) Increases cholesterol
b) Lowers LDL cholesterol
c) Increases triglycerides
d) Reduces HDL cholesterol
Answer: b) Lowers LDL cholesterol
Rationale: Simvastatin, a statin, inhibits HMG-CoA reductase, reducing LDL cholesterol levels.
6. What is the primary therapeutic use of levothyroxine?
a) Treat hypothyroidism
b) Manage hypertension
c) Relieve pain
d) Prevent seizures
Answer: a) Treat hypothyroidism
Rationale: Levothyroxine replaces thyroid hormone in hypothyroidism, restoring normal
metabolism.
7. A patient is prescribed morphine for severe pain. What is the primary
therapeutic effect?
a) Increases alertness
b) Relieves pain by binding to opioid receptors
c) Increases heart rate
d) Reduces blood pressure
Answer: b) Relieves pain by binding to opioid receptors
Rationale: Morphine activates opioid receptors, altering pain perception and providing
analgesia.
8. What is the primary therapeutic use of amoxicillin?
a) Treat viral infections
b) Treat bacterial infections
2025/2026 Edition) | Nightingale College | Actual
Verified Questions and Answers
The 2025/2026 BSN 315 HESI Pharmacology V1 Exam package includes complete and
verified exam set aligned with the Nightingale College nursing curriculum. This set is carefully
structured to assess advanced pharmacological principles, medication administration, and safe
nursing practice.
Key Focus Areas:
Drug classifications and therapeutic uses, pharmacokinetics, dosage calculations, adverse
effects, contraindications, and clinical reasoning in patient medication management.
Answer Format
All correct answers are presented in bold and green with detailed rationales explaining the
underlying pharmacological concepts, ensuring accurate preparation for the BSN 315 HESI
Pharmacology V1 Exam (2025/2026).
Drug Classifications and Therapeutic Uses (10 Questions)
1. A patient is prescribed lisinopril for hypertension. What is the primary
therapeutic effect?
a) Increases blood pressure
b) Reduces blood pressure by inhibiting ACE
c) Increases heart rate
d) Promotes fluid retention
Answer: b) Reduces blood pressure by inhibiting ACE
Rationale: Lisinopril, an ACE inhibitor, reduces angiotensin II formation, leading to
vasodilation and decreased blood pressure.
2. What is the primary therapeutic use of metformin?
a) Treat bacterial infections
b) Manage type 2 diabetes mellitus
c) Prevent seizures
d) Reduce inflammation
Answer: b) Manage type 2 diabetes mellitus
Rationale: Metformin decreases hepatic glucose production and improves insulin sensitivity,
making it a first-line treatment for type 2 diabetes.
3. A patient is prescribed warfarin for atrial fibrillation. What is the primary
therapeutic effect?
a) Increases clotting
, b) Prevents clot formation
c) Increases heart rate
d) Reduces blood pressure
Answer: b) Prevents clot formation
Rationale: Warfarin inhibits vitamin K-dependent clotting factors, reducing thrombus
formation.
4. What is the primary therapeutic use of albuterol?
a) Treat hypertension
b) Relieve bronchospasm in asthma/COPD
c) Reduce blood glucose
d) Prevent infections
Answer: b) Relieve bronchospasm in asthma/COPD
Rationale: Albuterol is a short-acting beta-2 agonist that bronchodilates, relieving respiratory
symptoms.
5. A patient is prescribed simvastatin for hyperlipidemia. What is the primary
therapeutic effect?
a) Increases cholesterol
b) Lowers LDL cholesterol
c) Increases triglycerides
d) Reduces HDL cholesterol
Answer: b) Lowers LDL cholesterol
Rationale: Simvastatin, a statin, inhibits HMG-CoA reductase, reducing LDL cholesterol levels.
6. What is the primary therapeutic use of levothyroxine?
a) Treat hypothyroidism
b) Manage hypertension
c) Relieve pain
d) Prevent seizures
Answer: a) Treat hypothyroidism
Rationale: Levothyroxine replaces thyroid hormone in hypothyroidism, restoring normal
metabolism.
7. A patient is prescribed morphine for severe pain. What is the primary
therapeutic effect?
a) Increases alertness
b) Relieves pain by binding to opioid receptors
c) Increases heart rate
d) Reduces blood pressure
Answer: b) Relieves pain by binding to opioid receptors
Rationale: Morphine activates opioid receptors, altering pain perception and providing
analgesia.
8. What is the primary therapeutic use of amoxicillin?
a) Treat viral infections
b) Treat bacterial infections
