NAGELHOUT PHARM 1 EXAM 3 COMPLETE QUESTIONS AND 100%
VERIFIED ANSWERS
Which opiate is the least effective? ANSWER Codeine.
0.04 potency in comparison to morphine.
F or T. Sufentanil and other high-dose opioids fulfill all the requirements for
general anesthesia. ANSWER Not true.
To induce forgetfulness or unconsciousness, relaxation, and sympathetic
control, more medications would be required.
Which opioid is the strongest? ANSWER 500–1000 suffentanil is just as
powerful as morphine sulfate.
Sort the following medications: meperidine, fentanil, codeine, alfentanil,
sufentanil, morphine, and remifentanil, in order of potency. ANSWER 1. 0.04
for Codeine
2. Fentanil 100 3. Alfentanil 10 4. Morphine 1 3. Meperidine 0.1
6. 100 Remifentanil
7. 1,000 Sufentanil
F or T. Giving fentanyl to a person who is allergic to morphine is acceptable.
The answer is yes.
One derivative of piperidine is fentanyl. The alkaloid phenantrene is what
morphine is. Drugs in the same classes can cause cross allergies.
T or F: Does the metabolite of morphine have negligible analgesic effects?
ANSWER Not true.
They have a strong analgesic effect. Repetitive dosage in renal patients may
result in accumulation.
Which opioid class is most appropriate for asthmatic patients? ANSWER
fentanil (phenylpiperadines) (no histamine release)
Which opioid contains a CNS-toxic metabolite? - ANSWER Meperidine.
Seizures are caused by the metabolite normeperidine. usage with caution in
older patients, those with renal impairment, or when used frequently.
, Which opioid is broken down by enzymes that don't require esterase?
ANSWER Remifentanil
This is accomplished by the blood plasma's ester bonds hydrolyzing.
What is Remifentanil's half-life of elimination? - REPLY 5–10 minutes
The anti-shivering properties of remifentanil are T or F. ANSWER: Untrue.
Meperidine is the only drug that provides anti-shivering properties.
Which of the following stimuli—skin incision, skin closure, or intubation—
requires the highest dosage of drugs to produce no response? ANSWER
Intubation
F or T. Opioids have the ability to prevent vomiting. ANSWER It's true.
They suppress the vomiting center, particularly when used frequently.
Which receptors provide opiates their analgesic and ventilatory lowering
effects? ANSWER Mu
T or F: Does naloxone block opioid receptors on ALL of them? The answer is
yes.
What side effects might a patient on a monoamine oxidase inhibitor and
receiving meperidine experience? ANSWER SEIZURES
Clonic, agitated, hyperreflexive, and hyperthermic symptoms of a
serotoninergic crisis
What is beta-endorphin's precursor molecule? ANSWER POMC, or pro-
ipiomelanocortin.
Which chemical serves as the precursor of enkephalins? ANSWER
Proenkaphalin A
Which chemical serves as the precursor of dynorphins? PRODYNORPHIN
ANSWER
Which bodily systems are affected by drugs? ANSWER 1. CNS
2. The GI system
What is multimodal therapy's ultimate objective in terms of pain relief?
ANSWER To enhance anti-nociception and reduce adverse effects, particularly
VERIFIED ANSWERS
Which opiate is the least effective? ANSWER Codeine.
0.04 potency in comparison to morphine.
F or T. Sufentanil and other high-dose opioids fulfill all the requirements for
general anesthesia. ANSWER Not true.
To induce forgetfulness or unconsciousness, relaxation, and sympathetic
control, more medications would be required.
Which opioid is the strongest? ANSWER 500–1000 suffentanil is just as
powerful as morphine sulfate.
Sort the following medications: meperidine, fentanil, codeine, alfentanil,
sufentanil, morphine, and remifentanil, in order of potency. ANSWER 1. 0.04
for Codeine
2. Fentanil 100 3. Alfentanil 10 4. Morphine 1 3. Meperidine 0.1
6. 100 Remifentanil
7. 1,000 Sufentanil
F or T. Giving fentanyl to a person who is allergic to morphine is acceptable.
The answer is yes.
One derivative of piperidine is fentanyl. The alkaloid phenantrene is what
morphine is. Drugs in the same classes can cause cross allergies.
T or F: Does the metabolite of morphine have negligible analgesic effects?
ANSWER Not true.
They have a strong analgesic effect. Repetitive dosage in renal patients may
result in accumulation.
Which opioid class is most appropriate for asthmatic patients? ANSWER
fentanil (phenylpiperadines) (no histamine release)
Which opioid contains a CNS-toxic metabolite? - ANSWER Meperidine.
Seizures are caused by the metabolite normeperidine. usage with caution in
older patients, those with renal impairment, or when used frequently.
, Which opioid is broken down by enzymes that don't require esterase?
ANSWER Remifentanil
This is accomplished by the blood plasma's ester bonds hydrolyzing.
What is Remifentanil's half-life of elimination? - REPLY 5–10 minutes
The anti-shivering properties of remifentanil are T or F. ANSWER: Untrue.
Meperidine is the only drug that provides anti-shivering properties.
Which of the following stimuli—skin incision, skin closure, or intubation—
requires the highest dosage of drugs to produce no response? ANSWER
Intubation
F or T. Opioids have the ability to prevent vomiting. ANSWER It's true.
They suppress the vomiting center, particularly when used frequently.
Which receptors provide opiates their analgesic and ventilatory lowering
effects? ANSWER Mu
T or F: Does naloxone block opioid receptors on ALL of them? The answer is
yes.
What side effects might a patient on a monoamine oxidase inhibitor and
receiving meperidine experience? ANSWER SEIZURES
Clonic, agitated, hyperreflexive, and hyperthermic symptoms of a
serotoninergic crisis
What is beta-endorphin's precursor molecule? ANSWER POMC, or pro-
ipiomelanocortin.
Which chemical serves as the precursor of enkephalins? ANSWER
Proenkaphalin A
Which chemical serves as the precursor of dynorphins? PRODYNORPHIN
ANSWER
Which bodily systems are affected by drugs? ANSWER 1. CNS
2. The GI system
What is multimodal therapy's ultimate objective in terms of pain relief?
ANSWER To enhance anti-nociception and reduce adverse effects, particularly
