ANPS 8005 Midterm Review Questions With Complete
Solutions
3h Post Injection Monitoring
Olanzapine Pamoate REMS program consists of?
BZDs
Major drug interaction that occurs when Olanzapine is given
parenterally within 1-2 hours of this medication?
Insomnia, Psychosis r/t Dementia, Children w/ Psychotic
Disorder
Antipsychotics should NOT be used as first line medication for
the which conditions?
Asenapine (Saphris)
This sublingual antipsychotic should not be taken within 10
minutes of food/drink?
Dystonia (muscle), Akathisia (rustle), Akinesia (hustle)
Symptoms of EPS/NMS include?
Dystonia
Symptom of EPS that is typically seen first, described as
torticollis and rapid contraction of facial and neck muscles?
Akathisia (rustle)
Symptom of EPS described as mounting sense of restlessness or
tension?
,Akinesia (hustle)
Symptom of EPS described as "cogwheeling" rigidity, tremor,
bradykinesia, shuffling gait, and postural instability; also
referred to as drug induced Parkinsonism?
Dantrolene (Dantrium)
Muscle relaxant used as first line treatment treatment for severe
NMS?
Anticholinergics (Benztropine), Antihistamines
(Diphenhydramine)
Treatment for acute dystonia associated with EPS?
Beta Blocker (low dose Propranolol), 5HT2A Antagonists
(Mirtazapine), BZDs
Treatment for acute akathisia associated with EPS?
Anticholinergic (Benztropine), Amantadine (Symmetrel) in
older adults)
Treatment for acute akinesia associated with EPS?
Tardive dyskinesia (TD)
Characterized by lip smacking, associated with chronic EPS?
Chronic D2 Blockade
Etiology of tardive dyskinesia?
VMAT2 Inhibitors (Valbenazine)
Treatment of tardive dyskinesia associated with antipsychotic
therapy?
, Functional Cooling, O2, Resp/Dysphagia Support, HOB
45degrees
Supportive care for patient experiencing NMS includes?
Wait 2 wks, Low (potency) and Slow (titration),
Process for restarting of antipsychotic post NMS?
Allergies (sesame oil)
When administering Haldol Decanoate the provider should be
aware of what?
Aristada Initio
Long acting antipsychotic medication that does not require PO
overlap?
Rapid Cycling
Disease process described as quick alternation between mania
and depression, with mania occurring at least 4 times per year?
Distractibility, Impulsivity, Grandiosity, Flight of Ideas, Activity
Increase, Sleep Decrease, Talkativeness
Symptoms associated with Bipolar Disorder?
mania (elevated/irritable mood) + 3 (or 4 or more if irritability)
symptoms within 1 week + with or without psychosis or
depression
Defining criteria of bipolar type 1 disorder?
mania (elevated/irritable mood) + 3 (or 4 or more if irritability)
symptoms within 4 consecutive days + with depression +
without psychosis
Solutions
3h Post Injection Monitoring
Olanzapine Pamoate REMS program consists of?
BZDs
Major drug interaction that occurs when Olanzapine is given
parenterally within 1-2 hours of this medication?
Insomnia, Psychosis r/t Dementia, Children w/ Psychotic
Disorder
Antipsychotics should NOT be used as first line medication for
the which conditions?
Asenapine (Saphris)
This sublingual antipsychotic should not be taken within 10
minutes of food/drink?
Dystonia (muscle), Akathisia (rustle), Akinesia (hustle)
Symptoms of EPS/NMS include?
Dystonia
Symptom of EPS that is typically seen first, described as
torticollis and rapid contraction of facial and neck muscles?
Akathisia (rustle)
Symptom of EPS described as mounting sense of restlessness or
tension?
,Akinesia (hustle)
Symptom of EPS described as "cogwheeling" rigidity, tremor,
bradykinesia, shuffling gait, and postural instability; also
referred to as drug induced Parkinsonism?
Dantrolene (Dantrium)
Muscle relaxant used as first line treatment treatment for severe
NMS?
Anticholinergics (Benztropine), Antihistamines
(Diphenhydramine)
Treatment for acute dystonia associated with EPS?
Beta Blocker (low dose Propranolol), 5HT2A Antagonists
(Mirtazapine), BZDs
Treatment for acute akathisia associated with EPS?
Anticholinergic (Benztropine), Amantadine (Symmetrel) in
older adults)
Treatment for acute akinesia associated with EPS?
Tardive dyskinesia (TD)
Characterized by lip smacking, associated with chronic EPS?
Chronic D2 Blockade
Etiology of tardive dyskinesia?
VMAT2 Inhibitors (Valbenazine)
Treatment of tardive dyskinesia associated with antipsychotic
therapy?
, Functional Cooling, O2, Resp/Dysphagia Support, HOB
45degrees
Supportive care for patient experiencing NMS includes?
Wait 2 wks, Low (potency) and Slow (titration),
Process for restarting of antipsychotic post NMS?
Allergies (sesame oil)
When administering Haldol Decanoate the provider should be
aware of what?
Aristada Initio
Long acting antipsychotic medication that does not require PO
overlap?
Rapid Cycling
Disease process described as quick alternation between mania
and depression, with mania occurring at least 4 times per year?
Distractibility, Impulsivity, Grandiosity, Flight of Ideas, Activity
Increase, Sleep Decrease, Talkativeness
Symptoms associated with Bipolar Disorder?
mania (elevated/irritable mood) + 3 (or 4 or more if irritability)
symptoms within 1 week + with or without psychosis or
depression
Defining criteria of bipolar type 1 disorder?
mania (elevated/irritable mood) + 3 (or 4 or more if irritability)
symptoms within 4 consecutive days + with depression +
without psychosis
