Week 4 Midterm Exam Practice NR 507/NR507
Questions and Answers
Defects in the encoding of histone-modifying proteins
1. Housekeeping Genes are vital to the function and maintenance of all the body’s cells. What
characteristic is … with these genes?
2. Mutations in the encoding of histone modifying proteins … shown to influence the development
of what congenital condition?
3. Epigenetics refers to chemical modification that are made to what?
4. Signals to change or modify epigenetic tags are … from where?
5. What sort of molecule is responsible for transferring signals into cells to gen regulatory proteins?
6. Mutations in the encoding of histone-modification proteins … shown to influence the
development of what congenial condition?
Epigenetics and its role on human development
1. Research has provided support for the theory that epigenetic modification can result from
deficient in utero nutrition causing?
2. During which stage of human development does the role of epigenetics have the greatest impact
on the development of epigenetic abnormalities?
3. The difference between DNA sequence mutations and epigenetic modifications is?
4. Research has provided support for the theory that epigenetic modification can result from
deficient in utero nutrition causing which chronic disease?
Totipotent cells and its ability to differentiate into any type of cell
1. Which embryonic stem cell characteristic is referred to as a totipotent?
2. Examples of two totipotent cells are?
, 3. What is a Totipotent cell?
4. Are all cells Totipotent cells?
Prader-Willi syndrome and Angelman syndrome?
1. What characteristic of Prader-Willi syndrome is not a characteristic of Angelman syndrome?
2. A child with Prader-Willi syndrome has been hospitalized. Which assessment findings does the
nurse expect with this syndrome?
3. The nurse is examining an 8-year-old boy with chromosomal abnormalities. Which sign or
symptom suggests the boy has Angelman syndrome?
Cellular Proliferation
5-Azacytidine and the treatment of cancer
1. What is 5-azacytidine? Nucleoside analog able to … incorporated into RNA & DNA
2. 5- Azactytide has demonstrated promise in the treatment of which form of cancer?
the role of inactive MLH1 in the development of some forms of inherited colon cancer
1. What is the role of inactive MLH1 in the development of some forms of inherited colon cancer?
Effects of ethanol on neural stem cells ability to differentiate into functional neurons-
1. Research has demonstrated that neural stem cells have an impaired ability to differentiate into
functional neurons when subjected to?
Inflammation as an etiology for cancer-note conditions in which this may occur
1. What chronic inflammatory conditions can increase risk for cancer?
Cancer
Questions and Answers
Defects in the encoding of histone-modifying proteins
1. Housekeeping Genes are vital to the function and maintenance of all the body’s cells. What
characteristic is … with these genes?
2. Mutations in the encoding of histone modifying proteins … shown to influence the development
of what congenital condition?
3. Epigenetics refers to chemical modification that are made to what?
4. Signals to change or modify epigenetic tags are … from where?
5. What sort of molecule is responsible for transferring signals into cells to gen regulatory proteins?
6. Mutations in the encoding of histone-modification proteins … shown to influence the
development of what congenial condition?
Epigenetics and its role on human development
1. Research has provided support for the theory that epigenetic modification can result from
deficient in utero nutrition causing?
2. During which stage of human development does the role of epigenetics have the greatest impact
on the development of epigenetic abnormalities?
3. The difference between DNA sequence mutations and epigenetic modifications is?
4. Research has provided support for the theory that epigenetic modification can result from
deficient in utero nutrition causing which chronic disease?
Totipotent cells and its ability to differentiate into any type of cell
1. Which embryonic stem cell characteristic is referred to as a totipotent?
2. Examples of two totipotent cells are?
, 3. What is a Totipotent cell?
4. Are all cells Totipotent cells?
Prader-Willi syndrome and Angelman syndrome?
1. What characteristic of Prader-Willi syndrome is not a characteristic of Angelman syndrome?
2. A child with Prader-Willi syndrome has been hospitalized. Which assessment findings does the
nurse expect with this syndrome?
3. The nurse is examining an 8-year-old boy with chromosomal abnormalities. Which sign or
symptom suggests the boy has Angelman syndrome?
Cellular Proliferation
5-Azacytidine and the treatment of cancer
1. What is 5-azacytidine? Nucleoside analog able to … incorporated into RNA & DNA
2. 5- Azactytide has demonstrated promise in the treatment of which form of cancer?
the role of inactive MLH1 in the development of some forms of inherited colon cancer
1. What is the role of inactive MLH1 in the development of some forms of inherited colon cancer?
Effects of ethanol on neural stem cells ability to differentiate into functional neurons-
1. Research has demonstrated that neural stem cells have an impaired ability to differentiate into
functional neurons when subjected to?
Inflammation as an etiology for cancer-note conditions in which this may occur
1. What chronic inflammatory conditions can increase risk for cancer?
Cancer
