NPTE Medications Questions with Detailed Verified Answers

NPTE Medications Questions with Detailed
Verified Answers
Aspirin Ans: - Type of COX inhibitor

- Inhibits prostaglandins (mediators of inflammatory process)

- Indications

1) fever reducer

2) pain reliever

3) anti-inflammatory

4) decrease blood clotting

Adverse effects of Aspirin Ans: - Prolonged bleeding

- GI bleeding

- Competes with anti-coagulant, anti-seizure, and cancer drunks

NSAIDs Ans: ie. Ibuprofin = non-selective COX inhibitors

1) Fever reducer

2) Pain reliever

3) Anti-inflammatory

Side effects of NSAIDs Ans: - Fluid retention

- Edema

- GI issues

, - Increased bleeding

examples of NSAIDS Ans: aspirin, ibuprofen, naproxen (aleve)

COX-2 NSAIDs Ans: - Selectively inhibit COX-2 inhibitors

- Good for RA & DJD

examples of COX-2 NSAIDS Ans: Colecoxib (Vioxx, Celebrex, Betra) for RA and
DJD

Side effects of COX-2 NSAIDs Ans: Fatal cardiac effects, therefore very few uses

Glucocorticosteroids Ans: ie. cortisol/hydrocortisone

- potent anti-inflammatory by:

1) capillary dilation

2) edema formation

3) migration of leukocytes/macrophages

Side effects of glucocorticosteroids Ans: - Adrenal insufficiency; fever & malaise

- Immunosuppression; increased risk of infection

- Depression, anxiety

- Cataracts

- Cushingoid state

- Fluid retention



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