PAST 421 - Pharm Challenge Questions - Exam 1
Questions with Detailed Verified Answers
Finasteride has efficacy in the prevention of male-pattern baldness by virtue of its
ability to do which of the following?
(A) Competitively antagonize androgen receptors
(B) Decrease the release of gonadotropins
(C) Increase the serum concentration of sex hormone-binding globulin
(D) Inhibit the synthesis of testosterone
(E) Reduce the production of dihydrotestosterone Ans: (E) Reduce the production of
dihydrotestosterone
BC is a 55 year old male with BPH. His PSA is 1.4 ng/ml & his prostate size is 15 g.
Symptoms include urinary frequency, nocturia, and bladder fullness. BC does not
tolerate medications well often times suffering from orthostatic hypotension &
dizziness. His current blood pressure is 110/75 mmHg with a heart rate of 75. Please
select the best medication choice:
a.Dutasteride(Aovdart)
b.Alfuzosin(Uroxatral)
c.Finasteride (Proscar)
d.Prazosin(Minipress) Ans: b.Alfuzosin(Uroxatral)
Which of the following agents is specific for type II 5-alpha-reductase?
,a.Dutasteride(Avodart)
b.Alfuzosin(Uroxatral)
c.Tamsulosin(Flomax)
d.Finasteride (Proscar) Ans: d.Finasteride (Proscar)
Which of the following side effects is most common with tamsulosin(Flomax)?
a.Syncope
b.Orthostatic hypotension
c.Dizziness
d.Ejaculatory dysfunction Ans: d.Ejaculatory dysfunction
Which of the following medications is not recommended for treatment of BPH?
a.Terazosin (Hytrin)
b.Alfuzosin(Uroxatral)
c.Tamsulosin(Flomax)
d.Prazosin(Minipress) Ans: d.Prazosin(Minipress)
Which of the following phosphodiesteraseinhibitors (PDE-I) has the longest half-life?
© Get it right 2025 Getaway - Stuvia US All rights reserved
, a.Sildenafil (Viagra)
b.Vardenafil(Levitra)
c.Tadalafil(Cialis)
d.None of the above Ans: c.Tadalafil(Cialis)
Which one of the following answers is correct regarding phosphodiesteraseinhibitors
(PDE) and back pain?
a.Sildenafil (Viagra) causes back pain the most through inhibition of PDE type 5 enzyme
b.Tadalafil(Cialis) causes back pain the most through inhibition of PDE type 6 enzyme
c.Vardenafil(Levitra) causes back pain the most through inhibition of PDE type 11
enzyme
d.Tadalafil(Cialis) causes back pain the most through inhibition of PDE type 11 enzyme
Ans: d.Tadalafil(Cialis) causes back pain the most through inhibition of PDE type 11
enzyme
Which of the following ED drugs are FDA approved to be taken on a daily basis for
BPH?
a.Sildenafil (Viagra)
b.Vardenafil(Levitra)
c.Tadalafil(Cialis)
© Get it right 2025 Getaway - Stuvia US All rights reserved
Questions with Detailed Verified Answers
Finasteride has efficacy in the prevention of male-pattern baldness by virtue of its
ability to do which of the following?
(A) Competitively antagonize androgen receptors
(B) Decrease the release of gonadotropins
(C) Increase the serum concentration of sex hormone-binding globulin
(D) Inhibit the synthesis of testosterone
(E) Reduce the production of dihydrotestosterone Ans: (E) Reduce the production of
dihydrotestosterone
BC is a 55 year old male with BPH. His PSA is 1.4 ng/ml & his prostate size is 15 g.
Symptoms include urinary frequency, nocturia, and bladder fullness. BC does not
tolerate medications well often times suffering from orthostatic hypotension &
dizziness. His current blood pressure is 110/75 mmHg with a heart rate of 75. Please
select the best medication choice:
a.Dutasteride(Aovdart)
b.Alfuzosin(Uroxatral)
c.Finasteride (Proscar)
d.Prazosin(Minipress) Ans: b.Alfuzosin(Uroxatral)
Which of the following agents is specific for type II 5-alpha-reductase?
,a.Dutasteride(Avodart)
b.Alfuzosin(Uroxatral)
c.Tamsulosin(Flomax)
d.Finasteride (Proscar) Ans: d.Finasteride (Proscar)
Which of the following side effects is most common with tamsulosin(Flomax)?
a.Syncope
b.Orthostatic hypotension
c.Dizziness
d.Ejaculatory dysfunction Ans: d.Ejaculatory dysfunction
Which of the following medications is not recommended for treatment of BPH?
a.Terazosin (Hytrin)
b.Alfuzosin(Uroxatral)
c.Tamsulosin(Flomax)
d.Prazosin(Minipress) Ans: d.Prazosin(Minipress)
Which of the following phosphodiesteraseinhibitors (PDE-I) has the longest half-life?
© Get it right 2025 Getaway - Stuvia US All rights reserved
, a.Sildenafil (Viagra)
b.Vardenafil(Levitra)
c.Tadalafil(Cialis)
d.None of the above Ans: c.Tadalafil(Cialis)
Which one of the following answers is correct regarding phosphodiesteraseinhibitors
(PDE) and back pain?
a.Sildenafil (Viagra) causes back pain the most through inhibition of PDE type 5 enzyme
b.Tadalafil(Cialis) causes back pain the most through inhibition of PDE type 6 enzyme
c.Vardenafil(Levitra) causes back pain the most through inhibition of PDE type 11
enzyme
d.Tadalafil(Cialis) causes back pain the most through inhibition of PDE type 11 enzyme
Ans: d.Tadalafil(Cialis) causes back pain the most through inhibition of PDE type 11
enzyme
Which of the following ED drugs are FDA approved to be taken on a daily basis for
BPH?
a.Sildenafil (Viagra)
b.Vardenafil(Levitra)
c.Tadalafil(Cialis)
© Get it right 2025 Getaway - Stuvia US All rights reserved
