FAMILY MEDICINE COMAT EXAM
QUESTIONS WITH 100% CORRECT
ANSWERS | LATEST VERSION 2025/2026.
Treatment of infant with Hep B+ mom - ANS Hep B Ig within 12 hours of birth + vaccination
(prevents 90% of infection)
Adults at risk for Hep B - ANS Sexually-active persons w/ >1 partner in the last 6 months,
persons seeking evaluation/treatment for a STD, current/recent IVDU, MSM, health care and
public safety workers exposed to blood or body fluids, ESRD, HIV, chronic liver disease
Patients born between which years should be screened for HCV infection? - ANS 1945-1965
Varicella
Schedule
Contraindications - ANS 2 doses of vaccine are required, 4-8 weeks apart, regardless of age;
should not be given before 12 months
Non-immune pregnant women or immunocompromized should not receive the vaccination
until after delivery; household contacts of immunocompetent pregnant women need not delay
vaccination
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED
,Tdap schedule - ANS Recommended for adults 19-64 to replace the next booster dose of
tetanus; should be given to patients 65 years or older, regardless of interval since most recent
Td-containing vaccine
Td booster every 10 years
Clean, minor wound + tetanus vaccination within 10 years - ANS Do nothing
Potentially contaminated wound + >5 years since vaccination - ANS Give booster
High risk wound + unimmunized - ANS Give tetanus Ig + vaccination
MMR contraindications - ANS Neomycin allergy
Live-attenuated vaccine = not for pregnant or immunocompromized patients
Wait 3 months if blood or Ig products given
Rubella vaccination contraindications - ANS Vaccination should not occur if pregnant or
planning pregnancy in next 4 weeks
If patient is currently pregnant and non-immune, she should be vaccinated early in postpartum
period
Meningitis vaccine schedule - ANS 2 doses of MCV4 recommended for adolescents 11
through 18 years of age; first dose at 11 or 12 years of age, with booster dose at age 16
Pneumococcal vaccine schedule - ANS PPSV23: adult vaccination indications = chronic
diseases, functional asplenia, residents of long-term care facilities
PCV13: infants and toddlers at 2, 4, 6 and 12-15 months
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED
,PPSV23 - ANS Adult vaccination = chronic diseases, functional asplenia, residents of long-
term care facilities
PCV13 - ANS For infants and toddlers at 2, 4, 6 and 12-15 months
Pneumococcal polysaccharide vaccine - ANS >65 years old or <65 with chronic medical
conditions
2nd 5-year revaccination in patients with CKD, liver disease, immunodeficiency, asplenia
Influenza vaccine effectiveness - ANS 30-90%
Influenza vaccination schedule - ANS Recommended for kids 6 months and older; minimum
age for live, attenuated vaccine is 2 years (do not give to immunocompromised or those around
them)
Administer 2 doses (separated by 4 weeks) to children 6 months - 8 years who are receiving
seasonal vaccine for the first time, or who were vaccinated for the 1st time during the previous
influenza season but only received 1 dose
Intranasal influenza vaccine contraindications - ANS Pregnant or immunocompromised
patients
Influenza vaccine contraindications - ANS Egg allergies
HPV vaccination - ANS Recommended for all women and men 9-26 years
Most effective if given before female becomes sexually active; can be administered when
patient has abnormal Pap or when breast-feeding
Not recommended for use during pregnancy
3 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED
, Herpes Zoster vaccination - ANS Recommended for those 60 or older regardless of having
prior episode of herpes zoster
Colorectal cancer screening - ANS Screen with FOBT, sigmoidoscopy or colonoscopy in adults
beginning at age 50 and continuing until age 75
If family history, screen 10 years before cancer was found in the family member, or at 50 -
whichever is sooner
Recommend against screening when >85 years
Breast imaging in women <30 - ANS Do not do a mammogram; do ultrasound instead
Standard of care for all palpable breast masses in women >40 - ANS Biopsy
Mammogram schedule - ANS Every 2 years for women between ages 50-74
Cervical cancer screening indications - ANS Screen women age 21-65 via Pap smear cytology
every 3 years OR every 5 years via cytology + HPV testing starting at 30
Recommend against screening in women under 21
ACS recommends discontinuing at 70 but notes that a woman who has had 3 or more normal
Pap tests and non abnormal Pap tests in the last 10 years can safely stop
No screening in women who have had hysterectomy with cervix removal if no history of high
grade lesion
4 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED
QUESTIONS WITH 100% CORRECT
ANSWERS | LATEST VERSION 2025/2026.
Treatment of infant with Hep B+ mom - ANS Hep B Ig within 12 hours of birth + vaccination
(prevents 90% of infection)
Adults at risk for Hep B - ANS Sexually-active persons w/ >1 partner in the last 6 months,
persons seeking evaluation/treatment for a STD, current/recent IVDU, MSM, health care and
public safety workers exposed to blood or body fluids, ESRD, HIV, chronic liver disease
Patients born between which years should be screened for HCV infection? - ANS 1945-1965
Varicella
Schedule
Contraindications - ANS 2 doses of vaccine are required, 4-8 weeks apart, regardless of age;
should not be given before 12 months
Non-immune pregnant women or immunocompromized should not receive the vaccination
until after delivery; household contacts of immunocompetent pregnant women need not delay
vaccination
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED
,Tdap schedule - ANS Recommended for adults 19-64 to replace the next booster dose of
tetanus; should be given to patients 65 years or older, regardless of interval since most recent
Td-containing vaccine
Td booster every 10 years
Clean, minor wound + tetanus vaccination within 10 years - ANS Do nothing
Potentially contaminated wound + >5 years since vaccination - ANS Give booster
High risk wound + unimmunized - ANS Give tetanus Ig + vaccination
MMR contraindications - ANS Neomycin allergy
Live-attenuated vaccine = not for pregnant or immunocompromized patients
Wait 3 months if blood or Ig products given
Rubella vaccination contraindications - ANS Vaccination should not occur if pregnant or
planning pregnancy in next 4 weeks
If patient is currently pregnant and non-immune, she should be vaccinated early in postpartum
period
Meningitis vaccine schedule - ANS 2 doses of MCV4 recommended for adolescents 11
through 18 years of age; first dose at 11 or 12 years of age, with booster dose at age 16
Pneumococcal vaccine schedule - ANS PPSV23: adult vaccination indications = chronic
diseases, functional asplenia, residents of long-term care facilities
PCV13: infants and toddlers at 2, 4, 6 and 12-15 months
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED
,PPSV23 - ANS Adult vaccination = chronic diseases, functional asplenia, residents of long-
term care facilities
PCV13 - ANS For infants and toddlers at 2, 4, 6 and 12-15 months
Pneumococcal polysaccharide vaccine - ANS >65 years old or <65 with chronic medical
conditions
2nd 5-year revaccination in patients with CKD, liver disease, immunodeficiency, asplenia
Influenza vaccine effectiveness - ANS 30-90%
Influenza vaccination schedule - ANS Recommended for kids 6 months and older; minimum
age for live, attenuated vaccine is 2 years (do not give to immunocompromised or those around
them)
Administer 2 doses (separated by 4 weeks) to children 6 months - 8 years who are receiving
seasonal vaccine for the first time, or who were vaccinated for the 1st time during the previous
influenza season but only received 1 dose
Intranasal influenza vaccine contraindications - ANS Pregnant or immunocompromised
patients
Influenza vaccine contraindications - ANS Egg allergies
HPV vaccination - ANS Recommended for all women and men 9-26 years
Most effective if given before female becomes sexually active; can be administered when
patient has abnormal Pap or when breast-feeding
Not recommended for use during pregnancy
3 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED
, Herpes Zoster vaccination - ANS Recommended for those 60 or older regardless of having
prior episode of herpes zoster
Colorectal cancer screening - ANS Screen with FOBT, sigmoidoscopy or colonoscopy in adults
beginning at age 50 and continuing until age 75
If family history, screen 10 years before cancer was found in the family member, or at 50 -
whichever is sooner
Recommend against screening when >85 years
Breast imaging in women <30 - ANS Do not do a mammogram; do ultrasound instead
Standard of care for all palpable breast masses in women >40 - ANS Biopsy
Mammogram schedule - ANS Every 2 years for women between ages 50-74
Cervical cancer screening indications - ANS Screen women age 21-65 via Pap smear cytology
every 3 years OR every 5 years via cytology + HPV testing starting at 30
Recommend against screening in women under 21
ACS recommends discontinuing at 70 but notes that a woman who has had 3 or more normal
Pap tests and non abnormal Pap tests in the last 10 years can safely stop
No screening in women who have had hysterectomy with cervix removal if no history of high
grade lesion
4 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED
