ST
The Immune System – 4th
UV
IA_ Edition
AP
TEST BANK PR
O VE
Peter Parham
D?
Comprehensive Test Bank for Instructors
and Students
© Peter Parham
All rights reserved. Reproduction or distribution without permission is prohibited.
Created by MedConnoisseur ©2025/2026
,ST
TABLE OF CONTENTS
The Immune System – 4th Edition
UV
Peter Parham
IA_
1. Elements of the Immune System and Their Roles in Defense
2. Innate Immunity: The Immediate Response to Infection
AP
3. Innate Immunity: The Induced Response to Infection
4. Antibody Structure and the Generation of B-Cell Diversity
5. Antigen Recognition by T Lymphocytes
PR
6. The Development of B Lymphocytes
7. The Development of T Lymphocytes
8. T Cell–Mediated Immunity
O
9. Immunity Mediated by B Cells and Antibodies
10.Preventing Infection at Mucosal Surfaces
VE
11.Immunological Memory and Vaccination
12.Coevolution of Innate and Adaptive Immunity D?
13.Failures of the Body’s Defenses
14.IgE-Mediated Immunity and Allergy
15.Transplantation of Tissues and Organs
16.Disruption of Healthy Tissue by the Adaptive Immune Response
17.Cancer and Its Interactions with the Immune System
Created by MedConnoisseur ©2025/2026
,ST THE IMMUNE SYSTEM, FOURTH EDITION
CHAPTER 1: ELEMENTS OF THE IMMUNE SYSTEM
UV AND THEIR ROLES IN DEFENSE
© 2015 GARLAND SCIENCE
1–1
a.
b.
IA_
The last cases of smallpox were reported in the _____.
1950s
1960s
c. 1970s
d.
e.
1–2
1980s
1990s.
AP
The first line of defense against microorganisms that infect the body is referred to as
_____. PR
a. opportunistic immunity
b. innate immunity
c. adaptive immunity
d. primary immunity OV
e. central immunity.
1–3 Which of the following pairs is mismatched?
a. innate immunity: highly specialized defenses ED
b. secondary immune response: immunological memory
c. hematopoiesis: bone marrow
d. phagocytosis: uptake and killing of microbes
e. lymphocyte recirculation: continuous transport between blood and lymph. ?
1–4 All of the following are examples of chemical barriers of innate immunity except _____.
a. lactic acid
b. normal microbiota
c. lysozyme
d. fatty acids
e. proteases.
1–5 When effector lymphocytes secrete _____, an inflammatory response ensues.
a. lysozyme
b. defensins
c. lymph
d. sebum
e. cytokines.
1–6 The thin layer of cells that makes up the interior lining of the blood vessels is called the
_____.
a. mucosa
1
, ST
b.
c.
d.
epithelium
endothelium
connective tissue
e. lymphoid tissue.
UV
1–7 Identify the incorrect statement regarding hematopoiesis.
a. Hematopoiesis is a continuous process that occurs throughout one’s lifetime.
b. The location for hematopoiesis differs with age.
IA_
c. Self renewal is necessary to replenish the supply of hematopoietic stem cells.
d. Most hematopoiesis occurs in the bone marrow after birth.
e. Leukocytes, but not erythrocytes, must go through hematopoiesis in order to develop.
1–8
a.
b.
megakaryocytes
dendritic cells
AP
The progenitors of macrophages are _____.
c. monocytes
d.
e.
f.
neutrophils
erythrocytes
M cells.
PR
1–9
a.
b.
Plasma cells
Dendritic cells
OV
_____ act as cellular messengers by delivering degraded pathogens to lymphoid organs.
c. Large granular lymphocytes
d.
e.
1–10
Mast cells
Basophils.
Another name for a large granular lymphocyte is a _____.
ED
a.
b.
c.
d.
plasma cell
helper T cell
monocyte
natural killer cell
?
e. eosinophil.
1–11 Effector cells that secrete antibodies are known as _____.
a. natural killer cells
b. cytotoxic T cells
c. helper T cells
d. M cells
e. plasma cells
f. regulatory T cells.
1–12 Spherical regions in lymph nodes containing areas that are packed densely with
proliferating B cells are called _____.
a. efferent vessels
b. germinal centers
2
The Immune System – 4th
UV
IA_ Edition
AP
TEST BANK PR
O VE
Peter Parham
D?
Comprehensive Test Bank for Instructors
and Students
© Peter Parham
All rights reserved. Reproduction or distribution without permission is prohibited.
Created by MedConnoisseur ©2025/2026
,ST
TABLE OF CONTENTS
The Immune System – 4th Edition
UV
Peter Parham
IA_
1. Elements of the Immune System and Their Roles in Defense
2. Innate Immunity: The Immediate Response to Infection
AP
3. Innate Immunity: The Induced Response to Infection
4. Antibody Structure and the Generation of B-Cell Diversity
5. Antigen Recognition by T Lymphocytes
PR
6. The Development of B Lymphocytes
7. The Development of T Lymphocytes
8. T Cell–Mediated Immunity
O
9. Immunity Mediated by B Cells and Antibodies
10.Preventing Infection at Mucosal Surfaces
VE
11.Immunological Memory and Vaccination
12.Coevolution of Innate and Adaptive Immunity D?
13.Failures of the Body’s Defenses
14.IgE-Mediated Immunity and Allergy
15.Transplantation of Tissues and Organs
16.Disruption of Healthy Tissue by the Adaptive Immune Response
17.Cancer and Its Interactions with the Immune System
Created by MedConnoisseur ©2025/2026
,ST THE IMMUNE SYSTEM, FOURTH EDITION
CHAPTER 1: ELEMENTS OF THE IMMUNE SYSTEM
UV AND THEIR ROLES IN DEFENSE
© 2015 GARLAND SCIENCE
1–1
a.
b.
IA_
The last cases of smallpox were reported in the _____.
1950s
1960s
c. 1970s
d.
e.
1–2
1980s
1990s.
AP
The first line of defense against microorganisms that infect the body is referred to as
_____. PR
a. opportunistic immunity
b. innate immunity
c. adaptive immunity
d. primary immunity OV
e. central immunity.
1–3 Which of the following pairs is mismatched?
a. innate immunity: highly specialized defenses ED
b. secondary immune response: immunological memory
c. hematopoiesis: bone marrow
d. phagocytosis: uptake and killing of microbes
e. lymphocyte recirculation: continuous transport between blood and lymph. ?
1–4 All of the following are examples of chemical barriers of innate immunity except _____.
a. lactic acid
b. normal microbiota
c. lysozyme
d. fatty acids
e. proteases.
1–5 When effector lymphocytes secrete _____, an inflammatory response ensues.
a. lysozyme
b. defensins
c. lymph
d. sebum
e. cytokines.
1–6 The thin layer of cells that makes up the interior lining of the blood vessels is called the
_____.
a. mucosa
1
, ST
b.
c.
d.
epithelium
endothelium
connective tissue
e. lymphoid tissue.
UV
1–7 Identify the incorrect statement regarding hematopoiesis.
a. Hematopoiesis is a continuous process that occurs throughout one’s lifetime.
b. The location for hematopoiesis differs with age.
IA_
c. Self renewal is necessary to replenish the supply of hematopoietic stem cells.
d. Most hematopoiesis occurs in the bone marrow after birth.
e. Leukocytes, but not erythrocytes, must go through hematopoiesis in order to develop.
1–8
a.
b.
megakaryocytes
dendritic cells
AP
The progenitors of macrophages are _____.
c. monocytes
d.
e.
f.
neutrophils
erythrocytes
M cells.
PR
1–9
a.
b.
Plasma cells
Dendritic cells
OV
_____ act as cellular messengers by delivering degraded pathogens to lymphoid organs.
c. Large granular lymphocytes
d.
e.
1–10
Mast cells
Basophils.
Another name for a large granular lymphocyte is a _____.
ED
a.
b.
c.
d.
plasma cell
helper T cell
monocyte
natural killer cell
?
e. eosinophil.
1–11 Effector cells that secrete antibodies are known as _____.
a. natural killer cells
b. cytotoxic T cells
c. helper T cells
d. M cells
e. plasma cells
f. regulatory T cells.
1–12 Spherical regions in lymph nodes containing areas that are packed densely with
proliferating B cells are called _____.
a. efferent vessels
b. germinal centers
2
