PHARMACOTHERAPEUTICS
FOR ADVANCED PRACTICE
CAREGIVERS EXAM 2025/2026
1. Men using transdermal testosterone gel (AndroGel) should:
a. Apply it immediately before sleeping
b. Avoid physical activity after application
✅ c. Avoid skin-to-skin contact with pregnant women
d. Apply it to the face for better absorption
2. Education on androgens for male clients should include that:
a. They improve liver function
✅ b. Short-term use places the client at risk for cholestatic hepatitis and jaundice
c. They prevent acne
d. They cause hypotension
3. Decreased libido may occur:
✅ a. With androgen therapy
b. With antihypertensives
c. Only in postmenopausal women
d. Due to high testosterone levels
4. The FDA warning on androgens states that they may cause:
✅ a. Peliosis hepatis
b. Hepatitis C
c. Hypoglycemia
d. Kidney stones
5. Monitoring for clients using androgens should include:
✅ a. Lipid levels and liver function tests
b. Serum calcium and potassium
1
,c. CBC and urine protein
d. Blood pressure and ECG
6. Before and during androgen therapy, men must have a:
✅ a. Digital prostate exam
b. Chest X-ray
c. Doppler ultrasound
d. Liver biopsy
7. Absolute contraindications to estrogen therapy include:
✅ a. Clotting disorders
b. Osteoporosis
c. Hypertension
d. Anemia
8. Postmenopausal women with an intact uterus should not be prescribed:
✅ a. Estrogen alone
b. Estrogen and progesterone
c. Progesterone only
d. Testosterone
9. Estrogen use in women who experience migraines with aura is risky because:
✅ a. It increases the risk of stroke
b. It prevents migraines
c. It reduces bone loss
d. It increases fertility
10. Education for oral contraceptive users includes counseling on:
✅ a. Decreasing or not smoking
b. Taking with milk
c. Avoiding caffeine
d. Taking double doses if missed
2
,11. A woman taking rifampin and oral contraceptives should:
✅ a. Use a back-up birth control method such as condoms
b. Increase contraceptive dose
c. Take vitamins
d. Avoid water for one hour after medication
12. Gynecomastia with androgens:
✅ a. Is a rare occurrence
b. Is very common
c. Occurs only in elderly men
d. Occurs only in children
13. Low sperm levels due to androgens:
✅ a. Occur only with long-term use
b. Occur immediately
c. Never occur
d. Occur with short-term therapy
14. Menstrual irregularities and androgens:
✅ a. Are a potential side effect
b. Are prevented by therapy
c. Never occur
d. Only occur with estrogen use
15. Orthostatic hypotension may occur as a side effect of:
✅ a. Androgen therapy
b. Estrogen
c. Progesterone
d. Clomiphene
16. Acne may occur as a side effect of:
✅ a. Androgen therapy
b. Estrogen
c. Progesterone
d. Antibiotic therapy
3
, 17. CBC and C-reactive protein are:
✅ a. Not required in monitoring for androgen use
b. Essential in all clients
c. The main indicators of toxicity
d. Required before treatment only
18. Urinalysis for proteinuria is:
✅ a. Not required before and during androgen therapy
b. Required weekly
c. Mandatory before therapy
d. Used to monitor liver function
19. Doppler exam of testicular blood flow is:
✅ a. Not required before and during androgen therapy
b. Recommended for all clients
c. Used to check testosterone absorption
d. Mandatory for those over 50
20. Serum potassium and magnesium levels are:
✅ a. Not included in androgen monitoring
b. Required monthly
c. Indicators of testosterone levels
d. Used for renal function assessment
21. The effectiveness of combined oral contraceptives may decrease when taken with:
✅ a. Rifampin
b. Ibuprofen
c. Amoxicillin
d. Metronidazole
22. A nasal Staphylococcus aureus carrier should:
✅ a. Separate rifampin and oral contraceptive ingestion by at least an hour
b. Take both together for best effect
4
FOR ADVANCED PRACTICE
CAREGIVERS EXAM 2025/2026
1. Men using transdermal testosterone gel (AndroGel) should:
a. Apply it immediately before sleeping
b. Avoid physical activity after application
✅ c. Avoid skin-to-skin contact with pregnant women
d. Apply it to the face for better absorption
2. Education on androgens for male clients should include that:
a. They improve liver function
✅ b. Short-term use places the client at risk for cholestatic hepatitis and jaundice
c. They prevent acne
d. They cause hypotension
3. Decreased libido may occur:
✅ a. With androgen therapy
b. With antihypertensives
c. Only in postmenopausal women
d. Due to high testosterone levels
4. The FDA warning on androgens states that they may cause:
✅ a. Peliosis hepatis
b. Hepatitis C
c. Hypoglycemia
d. Kidney stones
5. Monitoring for clients using androgens should include:
✅ a. Lipid levels and liver function tests
b. Serum calcium and potassium
1
,c. CBC and urine protein
d. Blood pressure and ECG
6. Before and during androgen therapy, men must have a:
✅ a. Digital prostate exam
b. Chest X-ray
c. Doppler ultrasound
d. Liver biopsy
7. Absolute contraindications to estrogen therapy include:
✅ a. Clotting disorders
b. Osteoporosis
c. Hypertension
d. Anemia
8. Postmenopausal women with an intact uterus should not be prescribed:
✅ a. Estrogen alone
b. Estrogen and progesterone
c. Progesterone only
d. Testosterone
9. Estrogen use in women who experience migraines with aura is risky because:
✅ a. It increases the risk of stroke
b. It prevents migraines
c. It reduces bone loss
d. It increases fertility
10. Education for oral contraceptive users includes counseling on:
✅ a. Decreasing or not smoking
b. Taking with milk
c. Avoiding caffeine
d. Taking double doses if missed
2
,11. A woman taking rifampin and oral contraceptives should:
✅ a. Use a back-up birth control method such as condoms
b. Increase contraceptive dose
c. Take vitamins
d. Avoid water for one hour after medication
12. Gynecomastia with androgens:
✅ a. Is a rare occurrence
b. Is very common
c. Occurs only in elderly men
d. Occurs only in children
13. Low sperm levels due to androgens:
✅ a. Occur only with long-term use
b. Occur immediately
c. Never occur
d. Occur with short-term therapy
14. Menstrual irregularities and androgens:
✅ a. Are a potential side effect
b. Are prevented by therapy
c. Never occur
d. Only occur with estrogen use
15. Orthostatic hypotension may occur as a side effect of:
✅ a. Androgen therapy
b. Estrogen
c. Progesterone
d. Clomiphene
16. Acne may occur as a side effect of:
✅ a. Androgen therapy
b. Estrogen
c. Progesterone
d. Antibiotic therapy
3
, 17. CBC and C-reactive protein are:
✅ a. Not required in monitoring for androgen use
b. Essential in all clients
c. The main indicators of toxicity
d. Required before treatment only
18. Urinalysis for proteinuria is:
✅ a. Not required before and during androgen therapy
b. Required weekly
c. Mandatory before therapy
d. Used to monitor liver function
19. Doppler exam of testicular blood flow is:
✅ a. Not required before and during androgen therapy
b. Recommended for all clients
c. Used to check testosterone absorption
d. Mandatory for those over 50
20. Serum potassium and magnesium levels are:
✅ a. Not included in androgen monitoring
b. Required monthly
c. Indicators of testosterone levels
d. Used for renal function assessment
21. The effectiveness of combined oral contraceptives may decrease when taken with:
✅ a. Rifampin
b. Ibuprofen
c. Amoxicillin
d. Metronidazole
22. A nasal Staphylococcus aureus carrier should:
✅ a. Separate rifampin and oral contraceptive ingestion by at least an hour
b. Take both together for best effect
4
