, Introduction to Organic and
Medicinal Chemistry
This text is designed to be an undergraduate reference textbook for students of
chemistry who aim to select degree modules geared towards medicinal chemistry.
The first two chapters offer an overview of basic organic chemistry, followed by
organic synthesis in Chapter 3, with an emphasis on the importance of synthetic
procedures in relation to the chemistry of drug design. In Chapter 4, the book covers
foundational aspects of biochemistry and biomedical science to provide a basis for
students understanding where and how drugs work on selected targets. Later, the
book explains how medicines have been created for selected topics in medicinal
chemistry – namely against pathogens, cancer and neurological targets.
Features:
• User-friendly text that deals with key methods in organic synthesis and
medicinal chemistry
• An overture of drug design against disease targets
• An introduction to the molecular basis of disease and key topics in medici-
nal chemistry
• Geared towards chemistry undergraduates with an interest in pursuing
medicinal chemistry further into their degree
• A complete set of tutorial questions and answers for each chapter
Nathan Keighley studied chemistry at the University of York, with selected option
modules in medicinal chemistry and organic synthesis. It was this course content
that inspired the writing of this textbook, Introduction to Organic and Medicinal
Chemistry because he hoped to pass on his interest in the subject to current students
of organic and medicinal chemistry. Nathan then focused his studies into organic
chemistry with a PhD in Environmental Chemistry, researching how organic mol-
ecules used in agriculture biodegrade in the environment to mitigate pollution, and
later applied this skillset into a career in industry. Chemistry is a highly relevant sub-
ject to modern life and Nathan wishes the students who use this book the best of luck
with their exams and hopes that they too are inspired to work in this most important
of scientific fields.
, Introduction to Organic and
Medicinal Chemistry
Nathan Keighley