Lipid Formation
and Metabolism
Dr Paul Hamilton
Clinical Reader, Queen’s University Belfast
Consultant Chemical Pathologist, Belfast Health and Social Care Trust
October 2024
, Learning Outcomes
• Describe the structure of biologically important lipids
• Outline the in vivo transport of lipids
• Describe the exogenous pathway of lipid metabolism
• Describe the endogenous pathway of lipid metabolism
• Detail the uptake of low density lipoprotein cholesterol
into cells and how this is regulated
• Understand the process of reverse cholesterol transport
• Understand the process of fatty acid oxidation and
synthesis
• Describe the metabolism of ketone bodies
,www.menti.com
Code 5299 6489
, Why do I need to know this?
• Fundamental to workings of the body
• Problems cause disease
– Heart attacks
– Strokes
– Aneurysms
– Diabetic emergencies
– Rare metabolic diseases
and Metabolism
Dr Paul Hamilton
Clinical Reader, Queen’s University Belfast
Consultant Chemical Pathologist, Belfast Health and Social Care Trust
October 2024
, Learning Outcomes
• Describe the structure of biologically important lipids
• Outline the in vivo transport of lipids
• Describe the exogenous pathway of lipid metabolism
• Describe the endogenous pathway of lipid metabolism
• Detail the uptake of low density lipoprotein cholesterol
into cells and how this is regulated
• Understand the process of reverse cholesterol transport
• Understand the process of fatty acid oxidation and
synthesis
• Describe the metabolism of ketone bodies
,www.menti.com
Code 5299 6489
, Why do I need to know this?
• Fundamental to workings of the body
• Problems cause disease
– Heart attacks
– Strokes
– Aneurysms
– Diabetic emergencies
– Rare metabolic diseases
