NUR 370 (Hematological - Exam 3) Questions
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Terms in this set (32)
Oxygen de-saturation (cell changes to sickled shape)
Causes vaso-occlusion & micro-cirrculation, from
obstruction
Sickle Cell Patho
Hemolysis (premaure destruction of RBC's)
(compensation with increased production)
Deoxygenate (get sticky and caught on each other)
- Anemia shows after 6mo
- Obstruction of microcirculation, ischemia
- Leg ulcers, Recurrent infections, Priapism,
Hematuria, Bone weakness, Enuresis
Sickle Cell CM's - Increased susceptibility to pneumococcal and
salmonella
- Poor feeding, poor weight gain, irritability, fatigue
- Chronic vaso-occlusion affecting any system
varies in severity and frequency
- Vaso-occlusive episode (VOE)
Sickle Cell Types of Crises - Splenic sequestration
- Aplastic crisis
- Painful episode
SCD; Vaso-Occlusive - Hypoxic damage, ischemia, necrosis, pain
Episode (VOE) Crisis - Can affect any body tissue or organ
- CM's depend on what tissue or organ is involved
SCD; Splenic Pooling of blood in the spleen and liver - hypotension
Sequestration Crisis & shock
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, 10/21/25, 4:6 AM
SCD; Aplastic Crisis Diminished or absent production of all blood cells
- S/S of crisis, importance of early intervention
- Prompt medical attention for fevers and other signs
of illness
- Maintaining hydration
- Recognize enuresis as a manifestation of the illness
Sickle Cell Disease Parent - Avoid under-medicating - pain prevention is needed
Teaching - Around the clock pain meds
- Psychological Support
- Heat packs NOT ICE
- Knowing that the pain they are feeling is real
- Recognition of complications, especially chest
syndrome or CVA
- Supplemental O2
- Transfusions
- Splenectomy
Sickle Cell Disease
- Chelation therapy w/Desferal (may need to be
Hospital Care During
reduced hemosiderosis due to iron overload)
Crisis
- Stem cell transplant
- Prevent the conditions that promote sickling
- Treat medical emergencies of sickle cell crisis
SCD; Hospital Care Maintain hydration and prevent
During Crisis - How to desaturation/hypoxemia
prevent the conditions
that promote sickling
SCD; Hospital Care - Bed rest to minimize O2 use
During Crisis - How to - Hydration
treat medical emergencies - Prevent/correct electrolyte imbalance or metabolic
of sickle cell crisis acidosis
Inadequate intake, excess demand, malabsorption, or
Patho for Iron Deficiency
impaired hemoglobin synthesis; overweight or
Anemia
underweight
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