Page 1 of 37
NBME 26 EXAM 1 NEWEST WITH 250 QUESTIONS
AND CORRECT VERIFIED WELL EXPLAINED
ANSWERS JUST RELEASED THIS YEAR
Question:
An 8-year-old girl is brought to the physician by her mother 1 hour after her cat scratched her
on her right arm. The mother says that the patient developed bright red streaks along her
a r m within minutes o f being scratched. T h e s c r a t c h e s w e r e painful, a n d t h e patient
w a s crying w h e n s h e s h o w e d t h e injury to h e r mother. Examination o f t h e right
forearm s h o w s t h e
surface linear streaks with intact skin, b u t there i s n o blood. T h e a p p e a r a n c e of t h e r e
d streaks m o s t likely indicated which o f t h e following h o s t r e s p o n s e s t o this injury?
A) Bacteria-generated capillary congestion
B) Complement-activated coagulation
C) Histamine-stimulated vasodilation
D+ IgE mediated eosinophil degranulation
E ) Trauma-induced arteriolar hemorrhage - CORRECT ANSWER✔✔C
Campared to X what is the relative risk of dying from coronary artery disease for Y?
Why u got it wrong??? - CORRECT ANSWER✔✔Deaths Y / Deaths X
1
SUCCESS!
,Page 2 of 37
Interpretation problem...
Deoxygenated blood carry more carbondioxide - CORRECT ANSWER✔✔Deoxygenated blood is
better buffer for hydrogen ions than hemoglobin
Small cell ca cause siadh - CORRECT ANSWER✔✔Hyponatremia is a cause of delirium
Mannitol infusion causes - CORRECT ANSWER✔✔Increased plasma osmolality
Increased ADH secretion
Proteasome inhibitors
- Bortezomib (Velcade)
- Carfilzomib (Kyprolis) - CORRECT ANSWER✔✔Induction of apoptosis
Mutation in long terminal chain - CORRECT ANSWER✔✔Integration of provirus into host cell
Nitropusside develops metabolic acidosis - CORRECT ANSWER✔✔Cyanide poisoning
Conversion into thiocyanite and accumulation in the liver
Decreased clearence by kidney
Bruising and menorrhagia
Antihemophilic factor 8 decreased
2
SUCCESS!
,Page 3 of 37
Decreased adhesion to collagen - CORRECT ANSWER✔✔Vwb
Question:
During a genome project, an experimental animal is found to have a DNA sequence with
similarities to a growth hormone receptor. Which of the following peptide segments shown is
the transmembrane segment?
A)
Ala Leu His Asp Ser Pro Glu Phe Tyr Asn Asp Asp Ser Trp Val Glu Phe Glu
B)
Leu Thr Glu Ser Asp Glu Glu Tyr Glu Leu Asp His Gln Lys Ser Gly Ala Lys Asp
C)
Asp Asp Ser Gly Arg Thr Ser Cys Glu Cys Gln Lys Thr Ser Leu Cys Ala Gly Leu
D)
Lys His Ala Ser Thr Arg His Thr Gly Ala Asn Arg Gly Ala Gly Leu
E)
3
SUCCESS!
, Page 4 of 37
Leu Val Leu Ile Phe Gly Met Ile Gly Val Val Val Val Val Leu Val Leu Leu Val Phe
F)
Gly Asp Gly Leu Ala Lys Leu Leu Leu Ser Gly Arg Ser Leu Ala Ala Gly - CORRECT ANSWER✔✔E
An 81-year-old woman is admitted to the hospital because of a massive pulmonary embolism
from a deep venous thrombosis. Her platelet count is 160,000/mm3. Appropriate
pharmacotherapy is started. One
week later, her platelet count is 55,000/mm3. The thrombocytopenia was most likely caused by
a drug with which of the following mechanisms of action?
A) Activates tissue plasminogen
B) Interferes with the carboxylation of coagulation factors
C) Irreversibly inactivates cyclooxygenase
D) Potentiates the action of antithrombin Ill
E) Selectively inhibits factor Xa - CORRECT ANSWER✔✔D
Person on ventilator - CORRECT ANSWER✔✔Cerebral vasoconstriction in ventilated patients =
hyperventilation → hypocapnia → ↓ cerebral blood flow
Fev/ fvc ratio<60 - CORRECT ANSWER✔✔Copd
Mother mom and aunt has a disease
Probability of boy having the disease - CORRECT ANSWER✔✔0.5 *0.5 =0.25
4
SUCCESS!
NBME 26 EXAM 1 NEWEST WITH 250 QUESTIONS
AND CORRECT VERIFIED WELL EXPLAINED
ANSWERS JUST RELEASED THIS YEAR
Question:
An 8-year-old girl is brought to the physician by her mother 1 hour after her cat scratched her
on her right arm. The mother says that the patient developed bright red streaks along her
a r m within minutes o f being scratched. T h e s c r a t c h e s w e r e painful, a n d t h e patient
w a s crying w h e n s h e s h o w e d t h e injury to h e r mother. Examination o f t h e right
forearm s h o w s t h e
surface linear streaks with intact skin, b u t there i s n o blood. T h e a p p e a r a n c e of t h e r e
d streaks m o s t likely indicated which o f t h e following h o s t r e s p o n s e s t o this injury?
A) Bacteria-generated capillary congestion
B) Complement-activated coagulation
C) Histamine-stimulated vasodilation
D+ IgE mediated eosinophil degranulation
E ) Trauma-induced arteriolar hemorrhage - CORRECT ANSWER✔✔C
Campared to X what is the relative risk of dying from coronary artery disease for Y?
Why u got it wrong??? - CORRECT ANSWER✔✔Deaths Y / Deaths X
1
SUCCESS!
,Page 2 of 37
Interpretation problem...
Deoxygenated blood carry more carbondioxide - CORRECT ANSWER✔✔Deoxygenated blood is
better buffer for hydrogen ions than hemoglobin
Small cell ca cause siadh - CORRECT ANSWER✔✔Hyponatremia is a cause of delirium
Mannitol infusion causes - CORRECT ANSWER✔✔Increased plasma osmolality
Increased ADH secretion
Proteasome inhibitors
- Bortezomib (Velcade)
- Carfilzomib (Kyprolis) - CORRECT ANSWER✔✔Induction of apoptosis
Mutation in long terminal chain - CORRECT ANSWER✔✔Integration of provirus into host cell
Nitropusside develops metabolic acidosis - CORRECT ANSWER✔✔Cyanide poisoning
Conversion into thiocyanite and accumulation in the liver
Decreased clearence by kidney
Bruising and menorrhagia
Antihemophilic factor 8 decreased
2
SUCCESS!
,Page 3 of 37
Decreased adhesion to collagen - CORRECT ANSWER✔✔Vwb
Question:
During a genome project, an experimental animal is found to have a DNA sequence with
similarities to a growth hormone receptor. Which of the following peptide segments shown is
the transmembrane segment?
A)
Ala Leu His Asp Ser Pro Glu Phe Tyr Asn Asp Asp Ser Trp Val Glu Phe Glu
B)
Leu Thr Glu Ser Asp Glu Glu Tyr Glu Leu Asp His Gln Lys Ser Gly Ala Lys Asp
C)
Asp Asp Ser Gly Arg Thr Ser Cys Glu Cys Gln Lys Thr Ser Leu Cys Ala Gly Leu
D)
Lys His Ala Ser Thr Arg His Thr Gly Ala Asn Arg Gly Ala Gly Leu
E)
3
SUCCESS!
, Page 4 of 37
Leu Val Leu Ile Phe Gly Met Ile Gly Val Val Val Val Val Leu Val Leu Leu Val Phe
F)
Gly Asp Gly Leu Ala Lys Leu Leu Leu Ser Gly Arg Ser Leu Ala Ala Gly - CORRECT ANSWER✔✔E
An 81-year-old woman is admitted to the hospital because of a massive pulmonary embolism
from a deep venous thrombosis. Her platelet count is 160,000/mm3. Appropriate
pharmacotherapy is started. One
week later, her platelet count is 55,000/mm3. The thrombocytopenia was most likely caused by
a drug with which of the following mechanisms of action?
A) Activates tissue plasminogen
B) Interferes with the carboxylation of coagulation factors
C) Irreversibly inactivates cyclooxygenase
D) Potentiates the action of antithrombin Ill
E) Selectively inhibits factor Xa - CORRECT ANSWER✔✔D
Person on ventilator - CORRECT ANSWER✔✔Cerebral vasoconstriction in ventilated patients =
hyperventilation → hypocapnia → ↓ cerebral blood flow
Fev/ fvc ratio<60 - CORRECT ANSWER✔✔Copd
Mother mom and aunt has a disease
Probability of boy having the disease - CORRECT ANSWER✔✔0.5 *0.5 =0.25
4
SUCCESS!
