TESTBANK t
RUBIN'SPATHOLOGY:CLINICOPATHOLOGICFOUNDATIONSOF MEDICINE
t t t t t
7TH EDITION
t t
DAVIDS.STRAYER,EMANUELRUBIN
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,Test Bank Rubin's Pathology: Clinicopathologic Foundations of Medicine 7th Edition
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Table of Contents:
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Chapter1: Cell Adaptation, Injury and Death
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Chapter2: Inflammation
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Chapter3: Repair, Regeneration and Fibrosis
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Chapter4: Immunopathology
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Chapter 5: Neoplasia
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Chapter 6: Developmental and Genetic Diseases
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Chapter 7: Hemodynamic Disorders
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Chapter 8: Environmental and Nutritional Pathology
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Chapter9: Infectious and Parasitic Diseases
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Section II: Pathogenesis of Systemic Conditions Expandable section
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Chapter 10: Aging
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Chapter 11: Systemic Autoimmune Diseases
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Chapter 12: Sepsis
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Chapter 13: Obesity and Diabetes Mellitus
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Chapter 14: The Pathology of Pregnancy
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Chapter 15: The Amyloidoses
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Section III: Diseases of Individual Organ SystemsExpandable section
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Chapter 16: Blood Vessels
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Chapter 17: The Heart
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Chapter 18: The Respiratory System
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Chapter 19: The Gastrointestinal Tract
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Chapter 20: The Liver and Biliary System
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Chapter 21: The Pancreas
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Chapter 22: The Kidney
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Chapter 23: The Lower Urinary Tract and Male Reproductive System
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Chapter 24: The Female Reproductive System and Peritoneum
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Chapter 25: The Breast
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Chapter 26: Hematopathology
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Chapter 27: The Endocrine System
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Chapter 28: The Skin
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Chapter 29: The Head and Neck
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Chapter 30: Bones, Joints and Soft Tissue
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Chapter31: Skeletal Muscle and Peripheral Nervous System
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Chapter32: The Central Nervous System
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Chapter 33: The Eye
t t t
Chapter 34: Forensic Pathology
t t t
,Rubin's Pathology: Clinicopathologic Foundations of
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MedicineChapter1:Cell Adaptation, Injuryand Death
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Ischemiaand other toxic injuries increase theaccumulation ofintracellular calcium as aresult
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1. of:
A) release ofstored calcium from the mitochondria. t t t t t t
B) improved intracellular volumeregulation. t t t
C) decreased influx acrossthecell membrane. t t t t t
D) attraction of calcium tofatty infiltrates. t t t t t
The patient is found to have liver disease, resulting in the removal of a lobe of his liver.
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2. Adaptation tothe reduced size ofthe liver leads to_ t ofthe remaining liver cells.
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A) metaplasia
B) organ atrophy t
C) compensatoryhyperplasia t
D) physiologic hypertrophy t
A person eating peanuts starts choking and collapses. His airway obstruction is partially cleared, but
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he remains hypoxic until hereaches the hospital. The prolonged cell hypoxia
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3. caused acerebral infarction and resulting
t t _ in thebrain. t t t t t t
A) caspaseactivation t
B) coagulation necrosis t
C) rapidphagocytosis t
D) protein p53 deficiency t t
Bacteriaand viruses cause cell damageby
t t t t t t ,which is unique from theintracellular
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4. damage caused by other injurious agents.
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A) disruptingthe sodium/potassium ATPase pump t t t t
B) interrupting oxidativemetabolism processes t t t
C) replicating and producing continued injury t t t t
D) decreasing protein synthesis andfunction t t t t
Thepatient has aprolonged interruption inarterial blood flowto his left kidney, causing
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5. hypoxiccell injuryand therelease of freeradicals. Free radicals damage cells by:
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A) destroying phospholipids inthecell membrane. t t t t t
B) alteringthe immune response of the cell. t t t t t t
C) disrupting calcium storage in thecell. t t t t t
D) inactivation ofenzymes and mitochondria. t t t t
, 6. Injured cells have impaired flow ofsubstances throughthecell membrane as aresult of:
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A) increased fat load. t t
B) alteredpermeability. t
C) altered glucoseutilization. t t
D) increased surfacereceptors. t t
7. Reversible adaptive intracellular responses areinitiated by: t t t t t t
A) stimulus overload. t
B) geneticmutations. t
C) chemicalmessengers. t
D) mitochondrialDNA. t
8. Injured cells become veryswollen as a result of:
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A) increased cell proteinsynthesis. t t t
B) altered cell volumeregulation. t t t
C) passive entry ofpotassium into the cell. t t t t t t
D) bleb formation in theplasmamembrane.
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Adiabeticpatient has impaired sensation, circulation, and oxygenation of his feet. Hesteps on a piece
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of glass, the wound does not heal, and the area tissue becomes necrotic. The necrotic
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9. celldeath is characterized by:
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A) rapidapoptosis. t
B) cellularrupture. t
C) shrinkageand collapse. t t
D) chronicinflammation. t
A 99-year-old woman has experienced the decline of cell function associated with age. A
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10. group oftheories ofcellular aging focus on programmed:
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A) changes withgenetic influences. t t t
B) elimination ofcell receptor sites. t t t t
C) insufficient telomeraseenzyme. t t
D) DNAmutation or faultyrepair. t t t t
An 89-year-old female patient has experienced significant decreases in her mobility and stamina
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during a3-week hospital stay forthetreatment of a femoral head fracture. Which of the following
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phenomena most likely accounts for the patients decrease in muscle function
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11. thatunderlies her reduced mobility?
t t t t
A) Impaired muscle cell metabolism resulting from metaplasia t t t t t t
B) Dysplasia as a consequence of inflammation during boneremodeling t t t t t t t t
C) Disuseatrophy ofmuscle cells during aprolonged period of immobility
t t t t t t t t t t
RUBIN'SPATHOLOGY:CLINICOPATHOLOGICFOUNDATIONSOF MEDICINE
t t t t t
7TH EDITION
t t
DAVIDS.STRAYER,EMANUELRUBIN
t t t t
,Test Bank Rubin's Pathology: Clinicopathologic Foundations of Medicine 7th Edition
t t t t t t t t t
Table of Contents:
t t
Chapter1: Cell Adaptation, Injury and Death
t t t t t t
Chapter2: Inflammation
t t
Chapter3: Repair, Regeneration and Fibrosis
t t t t t
Chapter4: Immunopathology
t t
Chapter 5: Neoplasia
t t
Chapter 6: Developmental and Genetic Diseases
t t t t t
Chapter 7: Hemodynamic Disorders
t t t
Chapter 8: Environmental and Nutritional Pathology
t t t t t
Chapter9: Infectious and Parasitic Diseases
t t t t t
Section II: Pathogenesis of Systemic Conditions Expandable section
t t t t t t t
Chapter 10: Aging
t t
Chapter 11: Systemic Autoimmune Diseases
t t t t
Chapter 12: Sepsis
t t
Chapter 13: Obesity and Diabetes Mellitus
t t t t t
Chapter 14: The Pathology of Pregnancy
t t t t t
Chapter 15: The Amyloidoses
t t t
Section III: Diseases of Individual Organ SystemsExpandable section
t t t t t t t
Chapter 16: Blood Vessels
t t t
Chapter 17: The Heart
t t t
Chapter 18: The Respiratory System
t t t t
Chapter 19: The Gastrointestinal Tract
t t t t
Chapter 20: The Liver and Biliary System
t t t t t t
Chapter 21: The Pancreas
t t t
Chapter 22: The Kidney
t t t
Chapter 23: The Lower Urinary Tract and Male Reproductive System
t t t t t t t t t
Chapter 24: The Female Reproductive System and Peritoneum
t t t t t t t
Chapter 25: The Breast
t t t
Chapter 26: Hematopathology
t t
Chapter 27: The Endocrine System
t t t t
Chapter 28: The Skin
t t t
Chapter 29: The Head and Neck
t t t t t
Chapter 30: Bones, Joints and Soft Tissue
t t t t t t
Chapter31: Skeletal Muscle and Peripheral Nervous System
t t t t t t t
Chapter32: The Central Nervous System
t t t t t
Chapter 33: The Eye
t t t
Chapter 34: Forensic Pathology
t t t
,Rubin's Pathology: Clinicopathologic Foundations of
t t t t
MedicineChapter1:Cell Adaptation, Injuryand Death
t t t t t t t
Ischemiaand other toxic injuries increase theaccumulation ofintracellular calcium as aresult
t t t t t t t t t t t t t
1. of:
A) release ofstored calcium from the mitochondria. t t t t t t
B) improved intracellular volumeregulation. t t t
C) decreased influx acrossthecell membrane. t t t t t
D) attraction of calcium tofatty infiltrates. t t t t t
The patient is found to have liver disease, resulting in the removal of a lobe of his liver.
t t t t t t t t t t t t t t t t t
2. Adaptation tothe reduced size ofthe liver leads to_ t ofthe remaining liver cells.
t t t t t t t t t t t t t
A) metaplasia
B) organ atrophy t
C) compensatoryhyperplasia t
D) physiologic hypertrophy t
A person eating peanuts starts choking and collapses. His airway obstruction is partially cleared, but
t t t t t t t t t t t t t t
he remains hypoxic until hereaches the hospital. The prolonged cell hypoxia
t t t t t t t t t t t t
3. caused acerebral infarction and resulting
t t _ in thebrain. t t t t t t
A) caspaseactivation t
B) coagulation necrosis t
C) rapidphagocytosis t
D) protein p53 deficiency t t
Bacteriaand viruses cause cell damageby
t t t t t t ,which is unique from theintracellular
t t t t t t
4. damage caused by other injurious agents.
t t t t t
A) disruptingthe sodium/potassium ATPase pump t t t t
B) interrupting oxidativemetabolism processes t t t
C) replicating and producing continued injury t t t t
D) decreasing protein synthesis andfunction t t t t
Thepatient has aprolonged interruption inarterial blood flowto his left kidney, causing
t t t t t t t t t t t t t t
5. hypoxiccell injuryand therelease of freeradicals. Free radicals damage cells by:
t t t t t t t t t t t t t
A) destroying phospholipids inthecell membrane. t t t t t
B) alteringthe immune response of the cell. t t t t t t
C) disrupting calcium storage in thecell. t t t t t
D) inactivation ofenzymes and mitochondria. t t t t
, 6. Injured cells have impaired flow ofsubstances throughthecell membrane as aresult of:
t t t t t t t t t t t t t t
A) increased fat load. t t
B) alteredpermeability. t
C) altered glucoseutilization. t t
D) increased surfacereceptors. t t
7. Reversible adaptive intracellular responses areinitiated by: t t t t t t
A) stimulus overload. t
B) geneticmutations. t
C) chemicalmessengers. t
D) mitochondrialDNA. t
8. Injured cells become veryswollen as a result of:
t t t t t t t t
A) increased cell proteinsynthesis. t t t
B) altered cell volumeregulation. t t t
C) passive entry ofpotassium into the cell. t t t t t t
D) bleb formation in theplasmamembrane.
t t t t t
Adiabeticpatient has impaired sensation, circulation, and oxygenation of his feet. Hesteps on a piece
t t t t t t t t t t t t t t t t
of glass, the wound does not heal, and the area tissue becomes necrotic. The necrotic
t t t t t t t t t t t t t t t
9. celldeath is characterized by:
t t t t
A) rapidapoptosis. t
B) cellularrupture. t
C) shrinkageand collapse. t t
D) chronicinflammation. t
A 99-year-old woman has experienced the decline of cell function associated with age. A
t t t t t t t t t t t t t
10. group oftheories ofcellular aging focus on programmed:
t t t t t t t t
A) changes withgenetic influences. t t t
B) elimination ofcell receptor sites. t t t t
C) insufficient telomeraseenzyme. t t
D) DNAmutation or faultyrepair. t t t t
An 89-year-old female patient has experienced significant decreases in her mobility and stamina
t t t t t t t t t t t t
during a3-week hospital stay forthetreatment of a femoral head fracture. Which of the following
t t t t t t t t t t t t t t t t t
phenomena most likely accounts for the patients decrease in muscle function
t t t t t t t t t t t
11. thatunderlies her reduced mobility?
t t t t
A) Impaired muscle cell metabolism resulting from metaplasia t t t t t t
B) Dysplasia as a consequence of inflammation during boneremodeling t t t t t t t t
C) Disuseatrophy ofmuscle cells during aprolonged period of immobility
t t t t t t t t t t
