APHON CHEMO COURSE EXAM QUESTIONS AND ANSWERS 100% CORRECT!!

aberrant cell division - ANSWER the primary characteristic of malignant cells tumor suppression genes - ANSWER these keep normal cellular growth in check by regulating cell division, DNA repair, and apoptosis; if damaged or absent, cells lack the appropriate growth-inhibiting signals and grow out of control nadir - ANSWER the period of time after a course of chemotherapy in which the patients blood counts are lowest physical barrier - ANSWER the first layer of defense that provides protective immunity through anatomic barriers; ex. skin, mucous membranes innate passive immunity - ANSWER the second layer of defense that provides rapid, nonspecific response to invading pathogens adaptive acquired immunity - ANSWER the third layer of defense tumor marker - ANSWER a characteristic feature or byproduct of a tumor cell that serves as a useful indication of tumor cell origin or tumor activity risk stratification - ANSWER allows for tailoring therapy after consideration of factors beyond those traditional staging systems; this approach allows for early intensification of treatment pharmacokinetics - ANSWER the movement of a drug in the body and studies how the body affects the administered drug chemotherapy - ANSWER drug therapy aimed at reducing visible tumor volume by cytotoxic effects and preventing tumor cell division and spread; agents are designed to kill malignant cells during different phases of the cell cycle radiation therapy - ANSWER the goal of treatment is to target the tumor for destruction while sparing the surrounding tissues autologous transplant - ANSWER the patient is both the donor and the recipient, often given as a "rescue" after high-dose chemo when immunosuppression or myelosuppression would be a dose-limiting factor; no risk of GVHD allogenic transplant - ANSWER donor and recipient are related or closely matched; donor is healthy syngeneic tranplant - ANSWER transplant source is from an identical twin immunotherapy - ANSWER biologic therapy that activates, modulates, or restores the patient's immune system in order to control the cancer molecular targeted therapy - ANSWER biologic therapy that act directly on a cancer cell to exert effect on a specific pathway or function