1
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Advanced Patho NSG5003 Immunity and
Infection Questions and Answers (100%
Correct Answers) Already Graded A+
Hypersensitivity is best defined as a(an):
A) Disturbance in the immunologic tolerance of self-antigens
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B) Immunologic reaction of one person to the tissue of another
person
C) Altered immunologic response to an antigen that results in
disease
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D) Undetectable immune response in the presence of antigens—
Ans: C) Altered immunologic response to an antigen that results in
disease
A hypersensitivity reaction that produces an allergic response is
called:
A) Hemolytic shock
B) Anaphylaxis
C) Necrotizing vasculitis
D) Systemic erythematosus—Ans: B) Anaphylaxis
The common hay fever allergy is expressed through a reaction
that is mediated by which class of immunoglobulins?
A) IgE
B) IgG
C) IgM
, 2
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D) T cells—Ans: A) IgE
Which type of antibody is involved in type I hypersensitivity
reaction?
A) IgA
B) IgE
C) IgG
D) IgM—Ans: B) IgE
Blood transfusion reactions are an example of:
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A) Autoimmunity
B) Alloimmunity
C) Homoimmunity
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D) Hypersensitivity—Ans: B) Alloimmunity
During an IgE-mediated hypersensitivity reaction, which leukocyte
is activated?
A) Neutrophils
B) Monocytes
C) Eosinophils
D) T lymphocytes—Ans: C) Eosinophils
During an IgE-mediated hypersensitivity reaction, what causes
bronchospasm?
A) Bronchial edema caused by the chemotactic factor of
anaphylaxis
B) Bronchial edema caused by binding of the cytotropic antibody
C) Smooth muscle contraction caused by histamine bound to H1
receptors
, 3
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D) Smooth muscle contraction caused by histamine bound to H2
receptors—Ans: C) Smooth muscle contraction caused by
histamine bound to H1 receptors
During an IgE-mediated hypersensitivity reaction, the
degranulation of mast cells is a result of which receptor action?
A) Histamine bound to H2
B) Chemotactic factor binding to the receptor
C) Epinephrine bound to mast cells
D) Acetylcholine bound to mast cells—Ans: A) Histamine bound
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to H2
What characteristic do atopic individuals have that make them
genetically predisposed to develop allergies?
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A) Greater quantities of histamine
B) More histamine receptors
C) Greater quantities of IgE
D) A deficiency in epinephrine—Ans: C) Greater quantities of IgE
What is the mechanism that results in type II hypersensitivity
reactions?
A) Antibodies coat mast cells by binding to receptors that signal its
degranulation, followed by a discharge of preformed mediators.
B) Antibodies bind to soluble antigens that were released into
body fluids, and the immune complexes are then deposited in the
tissues.
C) Cytotoxic T lymphocytes or lymphokine-producing helper T 1
cells directly attack and destroy cellular targets.
D) Antibodies bind to the antigens on the cell surface.—Ans: D)
Antibodies bind to the antigens on the cell surface.
, 4
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When mismatched blood is administered causing an ABO
incompatibility, the erythrocytes are destroyed by:
A) Complement-mediated cell lysis
B) Phagocytosis by macrophages
C) Phagocytosis in the spleen
D) Natural killer cells—Ans: A) Complement-mediated cell lysis
When antibodies are formed against red blood cell antigens of
the Rh system, the blood cells are destroyed by:
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A) Complement-mediated cell lysis
B) Phagocytosis by macrophages
C) Phagocytosis in the spleen
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D) Neutrophil granules and toxic oxygen products—Ans: C)
Phagocytosis in the spleen
When soluble antigens from infectious agents enter circulation,
tissue damage is a result of:
A) Complement-mediated cell lysis
B) Phagocytosis by macrophages
C) Phagocytosis in the spleen
D) Neutrophil granules and toxic oxygen products—Ans: D)
Neutrophil granules and toxic oxygen products
How are target cells destroyed in a type II hypersensitivity
reaction?
A) Complement-mediated cell lysis
B) Phagocytosis by macrophages
C) Neutrophil granules and toxic oxygen products
For Expert help and assignment solutions, +254707240657
Advanced Patho NSG5003 Immunity and
Infection Questions and Answers (100%
Correct Answers) Already Graded A+
Hypersensitivity is best defined as a(an):
A) Disturbance in the immunologic tolerance of self-antigens
© 2025 Assignment Expert
B) Immunologic reaction of one person to the tissue of another
person
C) Altered immunologic response to an antigen that results in
disease
Guru01 - Stuvia
D) Undetectable immune response in the presence of antigens—
Ans: C) Altered immunologic response to an antigen that results in
disease
A hypersensitivity reaction that produces an allergic response is
called:
A) Hemolytic shock
B) Anaphylaxis
C) Necrotizing vasculitis
D) Systemic erythematosus—Ans: B) Anaphylaxis
The common hay fever allergy is expressed through a reaction
that is mediated by which class of immunoglobulins?
A) IgE
B) IgG
C) IgM
, 2
For Expert help and assignment solutions, +254707240657
D) T cells—Ans: A) IgE
Which type of antibody is involved in type I hypersensitivity
reaction?
A) IgA
B) IgE
C) IgG
D) IgM—Ans: B) IgE
Blood transfusion reactions are an example of:
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A) Autoimmunity
B) Alloimmunity
C) Homoimmunity
Guru01 - Stuvia
D) Hypersensitivity—Ans: B) Alloimmunity
During an IgE-mediated hypersensitivity reaction, which leukocyte
is activated?
A) Neutrophils
B) Monocytes
C) Eosinophils
D) T lymphocytes—Ans: C) Eosinophils
During an IgE-mediated hypersensitivity reaction, what causes
bronchospasm?
A) Bronchial edema caused by the chemotactic factor of
anaphylaxis
B) Bronchial edema caused by binding of the cytotropic antibody
C) Smooth muscle contraction caused by histamine bound to H1
receptors
, 3
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D) Smooth muscle contraction caused by histamine bound to H2
receptors—Ans: C) Smooth muscle contraction caused by
histamine bound to H1 receptors
During an IgE-mediated hypersensitivity reaction, the
degranulation of mast cells is a result of which receptor action?
A) Histamine bound to H2
B) Chemotactic factor binding to the receptor
C) Epinephrine bound to mast cells
D) Acetylcholine bound to mast cells—Ans: A) Histamine bound
© 2025 Assignment Expert
to H2
What characteristic do atopic individuals have that make them
genetically predisposed to develop allergies?
Guru01 - Stuvia
A) Greater quantities of histamine
B) More histamine receptors
C) Greater quantities of IgE
D) A deficiency in epinephrine—Ans: C) Greater quantities of IgE
What is the mechanism that results in type II hypersensitivity
reactions?
A) Antibodies coat mast cells by binding to receptors that signal its
degranulation, followed by a discharge of preformed mediators.
B) Antibodies bind to soluble antigens that were released into
body fluids, and the immune complexes are then deposited in the
tissues.
C) Cytotoxic T lymphocytes or lymphokine-producing helper T 1
cells directly attack and destroy cellular targets.
D) Antibodies bind to the antigens on the cell surface.—Ans: D)
Antibodies bind to the antigens on the cell surface.
, 4
For Expert help and assignment solutions, +254707240657
When mismatched blood is administered causing an ABO
incompatibility, the erythrocytes are destroyed by:
A) Complement-mediated cell lysis
B) Phagocytosis by macrophages
C) Phagocytosis in the spleen
D) Natural killer cells—Ans: A) Complement-mediated cell lysis
When antibodies are formed against red blood cell antigens of
the Rh system, the blood cells are destroyed by:
© 2025 Assignment Expert
A) Complement-mediated cell lysis
B) Phagocytosis by macrophages
C) Phagocytosis in the spleen
Guru01 - Stuvia
D) Neutrophil granules and toxic oxygen products—Ans: C)
Phagocytosis in the spleen
When soluble antigens from infectious agents enter circulation,
tissue damage is a result of:
A) Complement-mediated cell lysis
B) Phagocytosis by macrophages
C) Phagocytosis in the spleen
D) Neutrophil granules and toxic oxygen products—Ans: D)
Neutrophil granules and toxic oxygen products
How are target cells destroyed in a type II hypersensitivity
reaction?
A) Complement-mediated cell lysis
B) Phagocytosis by macrophages
C) Neutrophil granules and toxic oxygen products
