SBB Review 255 Questions with Correct
Answers
Band 3 - ✅✅✅macro complex of proteins including:
-Rh
-Rag
-LW (ICAM-4)
-GPA
-GPB
-CD47
ATP source for RBCs - ✅✅✅90% from Glycolysis (Embden-
Meyerhoff pathway)
10% from pentose phosphate pathway
Met hemoglobin Reeducates Pathway - ✅✅✅necessary to maintain
home iron in ferrous (Fe2+) state
Deficiency causes accumulation of met hemoglobin, nonfunctional from
of Hob
Lumbering Rappaport Shunt - ✅✅✅permits accumulation of 2, 3-
DPG
P a g e 1 | 62
,"Tense form" of Hob - ✅✅✅DEOXYGENATED
Widening of beta-chain
Lower affinity for O2
Expels 2, 3-DPG
"Relaxed form" of Hob - ✅✅✅OXYGENATED
Beta-chain pulled together
Higher affinity for O2
Expels 2, 3-DPG
"Shift Right" - ✅✅✅higher P50 value
Decreased pH (increased H+ ion), acidosis
Increased 2, 3-DPG
Higher temperature
High pCO2
Seen in compensated anemia
"Shift Left" - ✅✅✅lower P50 value
Increased pH (decreased H+ ion), alkalosis
Decreased 2, 3-DPG
Lower temperatures
P a g e 2 | 62
,Low pCO2
Seen in storage of RBC
Type 2 precursor - ✅✅✅Gal-Glena
B1-4
Type 1 precursor - ✅✅✅Gal-Glena
B1-3
Secreted (Se, Le)
Type 2 H antigen transferees & Sugar - ✅✅✅FUT-1
Alpha-2-L-fucosyltransferase
Fructose alpha1-2
An antigen transferees & sugar - ✅✅✅D-galactosaminetrasferase
N-acetylgalactosamine alpha1-3
P a g e 3 | 62
, B antigen transferees & sugar - ✅✅✅D-galacotsyltransferase
GA lactose alpha1-3
Ax subgroup - ✅✅✅weakly positive anti-A
Weakly positive anti-A, B
Am subgroup - ✅✅✅Negative anti-A
Secretes A & H
Ale subgroup - ✅✅✅Negative anti-A
Secretes H only
Highest expression of H
Lowest expression of H - ✅✅✅O>A2>B>A2B>A1>A1B> H deficient
Lewis transferees & Sugar - ✅✅✅FUT-3
Fructose alpha1-4
Type 1 H antigen transferees & sugar - ✅✅✅FUT-2
P a g e 4 | 62
Answers
Band 3 - ✅✅✅macro complex of proteins including:
-Rh
-Rag
-LW (ICAM-4)
-GPA
-GPB
-CD47
ATP source for RBCs - ✅✅✅90% from Glycolysis (Embden-
Meyerhoff pathway)
10% from pentose phosphate pathway
Met hemoglobin Reeducates Pathway - ✅✅✅necessary to maintain
home iron in ferrous (Fe2+) state
Deficiency causes accumulation of met hemoglobin, nonfunctional from
of Hob
Lumbering Rappaport Shunt - ✅✅✅permits accumulation of 2, 3-
DPG
P a g e 1 | 62
,"Tense form" of Hob - ✅✅✅DEOXYGENATED
Widening of beta-chain
Lower affinity for O2
Expels 2, 3-DPG
"Relaxed form" of Hob - ✅✅✅OXYGENATED
Beta-chain pulled together
Higher affinity for O2
Expels 2, 3-DPG
"Shift Right" - ✅✅✅higher P50 value
Decreased pH (increased H+ ion), acidosis
Increased 2, 3-DPG
Higher temperature
High pCO2
Seen in compensated anemia
"Shift Left" - ✅✅✅lower P50 value
Increased pH (decreased H+ ion), alkalosis
Decreased 2, 3-DPG
Lower temperatures
P a g e 2 | 62
,Low pCO2
Seen in storage of RBC
Type 2 precursor - ✅✅✅Gal-Glena
B1-4
Type 1 precursor - ✅✅✅Gal-Glena
B1-3
Secreted (Se, Le)
Type 2 H antigen transferees & Sugar - ✅✅✅FUT-1
Alpha-2-L-fucosyltransferase
Fructose alpha1-2
An antigen transferees & sugar - ✅✅✅D-galactosaminetrasferase
N-acetylgalactosamine alpha1-3
P a g e 3 | 62
, B antigen transferees & sugar - ✅✅✅D-galacotsyltransferase
GA lactose alpha1-3
Ax subgroup - ✅✅✅weakly positive anti-A
Weakly positive anti-A, B
Am subgroup - ✅✅✅Negative anti-A
Secretes A & H
Ale subgroup - ✅✅✅Negative anti-A
Secretes H only
Highest expression of H
Lowest expression of H - ✅✅✅O>A2>B>A2B>A1>A1B> H deficient
Lewis transferees & Sugar - ✅✅✅FUT-3
Fructose alpha1-4
Type 1 H antigen transferees & sugar - ✅✅✅FUT-2
P a g e 4 | 62
