BPH NAPLEX Exam Questions with Verified Answers

BPH NAPLEX Exam Questions with Verified Answers testosterone is metabolized to - Answers dihydrotestosterone (DHT) by 5 alpha-reductase Drugs that can worsen BPH - Answers Centrally acting anticholinergics (benztropine) Drugs with anticholinergic effects: - antihistamines (diphenhydramine) - decongestants (pseudoephedrine) - Phenothiazines (prochlorperazine) - TCAs (amitriptyline) Caffeine Diuretics SNRIs Testosterone products exams for BPH - Answers digital rectal exam (DRE) and prostate-specific antigen (PSA) signs and sx of BPH - Answers hesitancy, intermittent urine flow, straining or a weak stream, urinary urgency and leaking or dribbling urinary freq esp nocturia if blockage is severe urine can back up into kidneys and result in - Answers acute renal failure sx of BPH can be similar to - Answers prostate cancer natural products for BPH - Answers saw palmetto natural product used for prostate cancer prevention - Answers Lycopene drug tx of BPH - Answers alpha blockers used alone or in combo with 5 alpha reductase inhibitors 5 alpha reductase inhibitors work by - Answers decreasing prostate size, but have delayed onset and should not be used in men without prostate enlargement other tx option for BPH - Answers PDE5 inhib with or without finasteride first line tx for BPH - Answers alpha 1 blockers alpha 1 blockers MOA - Answers Blocks alpha-1 receptors which causes relaxation of smooth muscle and reduces bladder obstruction which improves urinary flow non-selective alpha blockers (terazosin, doxazosin) have more - Answers side effects than selective alpha 1a blockers (tamsulosin, alfuzosin, silodosin) pts using alpha blockers are at risk of developing - Answers intraoperative floppy iris syndrome if cataract surgery is planned alpha blocker tx should be - Answers delayed until surgery has been completed non selective alpha 1 blockers - Answers Terazosin Doxazosin doxazosin - Answers Cardura, Cardura XL non selective alpha 1 blockers should be taken - Answers at bedtime and should be titrated slowly warnings of alpha 1 blockers - Answers orthostatic hypotension/syncope, and with PDE5 inhib started and intraoperative floppy iris syndrome can occur in cataract surgery side effects of alpha 1 blockers - Answers dizziness, fatigue, headache, abnormal ejaculation selective alpha 1a blockers - Answers Tamsulosin Alfuzosin Silodosin tamsulosin - Answers Flomax Tamsulosin dosing - Answers 0.4 mg daily nonselective alpha blockers are given at bedtime to minimize - Answers orthostasis/dizziness how many weeks may be required to assess whether beneficial effects have been achieved w