PRITE Ninja Exam Questions and Answers
60 yo right-handed M, getting lost, only writes on right half of paper. Left-sided hemi-neglect. Where is
the lesion? - ✅✅RIGHT PARIETAL LOBE
66 yo with HTN develops vertigo, diplopia, nausea, vomiting, hiccups, L face numbness, nystagmus,
hoarseness, ataxia of limbs, staggering gait, and tendency to fall to the left. Dx? - ✅✅LATERAL
MEDULLARY STROKE
26 yo w/HA and R-hand clumsiness for weeks. Exam shows difficutty w/rapid alternating movements of
hand, overt intention tremor on finger-to-nose, and mildly dysmetric finger tamping. CNS intact and no
papilledema. Where will damage show on MRI? - ✅✅CEREBELLUM
78 yo pt had an ischemic stroke that left him with a residual mild hemiplegia. Pt appeared to be
unaware that there was a problem of weakness on one side of this body. When asked to raise the weak
arm, the patient raised his normal arm. When the failure to raise the paralyzed arm was pointed out to
pt, he admitted that the arm was slightly weak. He also neglects the side of the body when dressing and
grooming. Pt did not shave one side of his face, had difficulty putting a shirt on when it was turned
inside out. Area of the brain likely affected by stroke? - ✅✅RIGHT PARIETAL LOBE
Adult neurogenesis happens in which area of the brain? - ✅✅HIPPOCAMPUS
Previously pleasant mom becomes profane and irresponsible over 6 months. Most likely a pathology in:
- ✅✅FRONTAL LOBE
In addiction, dopaminergic neurons project to nucleus accumbens. Cell bodies of these neurons reside in
which area of the brain? - ✅✅VENTRAL TEGMENTAL AREA
Orexin is made in what part of the brain? - ✅✅LATERAL HYPOTHALAMIC NUCLEI
Which dopaminergic pathway includes the nucleus accumbens and also mediates addiction and
associated behaviors/ reinforcing? - ✅✅MESOLIMBIC
, Neural plasticity is largely mediated through the capacity to rapidly change in number and morphology
of what cell structure? - ✅✅DENDRITIC SPINES
Which cell type secretes innate pro-inflammatory cytokines TNF - alpha and Il -1 B in pts with
inflammatory conditions that affect the brain? - ✅✅MICROGLIA
Cortical synaptic remodeling characteristic of normal adolescence is also believed to be associated with
what neurobiological change? - ✅✅PREFERENTIAL LOSS OF EXCITATORY SYNAPSES
DA release in what structure represents common final event associated w/ reinforcing effects of opiates,
cocaine, amphetamines, nicotine, PCP, and alcohol? - ✅✅NUCLEUS ACCUMBENS
In addiction, dopaminergic neurons project to nucleus accumbens. Cell bodies of these neurons reside in
which area of the brain? - ✅✅VENTRAL TEGMENTAL AREA
Neurohormone for social bonding: - ✅✅OXYTOCIN
Decreased level of what NT is most associated with depressed mood, poor sleep, and poor impulse
control, and affective aggression? - ✅✅SEROTONIN
Visual problem in pituitary tumor compressing optic chiasm: - ✅✅BITEMPORAL HEMIANOPSIA
Unsteady gait, appendicular ataxia in LE only and normal eye movement. Walks with lurching broad-
based gait. Dx? - ✅✅CEREBELLAR DEGENERATION (ALCOHOLIC)
66 yo c/o frequent falls, several-month hx of anxiety, unwillingness to leave home. On exam, mild
impairment of vertical gaze on smooth pursuit/saccades, mild axial rigidity & minimal rigidity of upper
extremities, along w/ mild slowness of movement on finger tapping, hand opening & wrist opposition.
Posture nml. Gait tentative/awkward, but w/o shuffling, ataxia, tremor. Pt is slow in arising from a chair.
Most likely dx: - ✅✅PROGRESSIVE SUPRANUCLEAR PALSY
60 yo right-handed M, getting lost, only writes on right half of paper. Left-sided hemi-neglect. Where is
the lesion? - ✅✅RIGHT PARIETAL LOBE
66 yo with HTN develops vertigo, diplopia, nausea, vomiting, hiccups, L face numbness, nystagmus,
hoarseness, ataxia of limbs, staggering gait, and tendency to fall to the left. Dx? - ✅✅LATERAL
MEDULLARY STROKE
26 yo w/HA and R-hand clumsiness for weeks. Exam shows difficutty w/rapid alternating movements of
hand, overt intention tremor on finger-to-nose, and mildly dysmetric finger tamping. CNS intact and no
papilledema. Where will damage show on MRI? - ✅✅CEREBELLUM
78 yo pt had an ischemic stroke that left him with a residual mild hemiplegia. Pt appeared to be
unaware that there was a problem of weakness on one side of this body. When asked to raise the weak
arm, the patient raised his normal arm. When the failure to raise the paralyzed arm was pointed out to
pt, he admitted that the arm was slightly weak. He also neglects the side of the body when dressing and
grooming. Pt did not shave one side of his face, had difficulty putting a shirt on when it was turned
inside out. Area of the brain likely affected by stroke? - ✅✅RIGHT PARIETAL LOBE
Adult neurogenesis happens in which area of the brain? - ✅✅HIPPOCAMPUS
Previously pleasant mom becomes profane and irresponsible over 6 months. Most likely a pathology in:
- ✅✅FRONTAL LOBE
In addiction, dopaminergic neurons project to nucleus accumbens. Cell bodies of these neurons reside in
which area of the brain? - ✅✅VENTRAL TEGMENTAL AREA
Orexin is made in what part of the brain? - ✅✅LATERAL HYPOTHALAMIC NUCLEI
Which dopaminergic pathway includes the nucleus accumbens and also mediates addiction and
associated behaviors/ reinforcing? - ✅✅MESOLIMBIC
, Neural plasticity is largely mediated through the capacity to rapidly change in number and morphology
of what cell structure? - ✅✅DENDRITIC SPINES
Which cell type secretes innate pro-inflammatory cytokines TNF - alpha and Il -1 B in pts with
inflammatory conditions that affect the brain? - ✅✅MICROGLIA
Cortical synaptic remodeling characteristic of normal adolescence is also believed to be associated with
what neurobiological change? - ✅✅PREFERENTIAL LOSS OF EXCITATORY SYNAPSES
DA release in what structure represents common final event associated w/ reinforcing effects of opiates,
cocaine, amphetamines, nicotine, PCP, and alcohol? - ✅✅NUCLEUS ACCUMBENS
In addiction, dopaminergic neurons project to nucleus accumbens. Cell bodies of these neurons reside in
which area of the brain? - ✅✅VENTRAL TEGMENTAL AREA
Neurohormone for social bonding: - ✅✅OXYTOCIN
Decreased level of what NT is most associated with depressed mood, poor sleep, and poor impulse
control, and affective aggression? - ✅✅SEROTONIN
Visual problem in pituitary tumor compressing optic chiasm: - ✅✅BITEMPORAL HEMIANOPSIA
Unsteady gait, appendicular ataxia in LE only and normal eye movement. Walks with lurching broad-
based gait. Dx? - ✅✅CEREBELLAR DEGENERATION (ALCOHOLIC)
66 yo c/o frequent falls, several-month hx of anxiety, unwillingness to leave home. On exam, mild
impairment of vertical gaze on smooth pursuit/saccades, mild axial rigidity & minimal rigidity of upper
extremities, along w/ mild slowness of movement on finger tapping, hand opening & wrist opposition.
Posture nml. Gait tentative/awkward, but w/o shuffling, ataxia, tremor. Pt is slow in arising from a chair.
Most likely dx: - ✅✅PROGRESSIVE SUPRANUCLEAR PALSY
