Answers
1. SSRI's -tines
-4-6 weeks for full effect (SNRI's are faster)
-causes insomnia, headache, nausea, sexual dysfunction
-monitor for SI
-dont stop abruptly
2. SNRI's -cause sedation
-hypertension
3. TCA's -sedation
-hypotension
-anticholinergic effect
4. Bupropion -atypical antidepressant
-dont give with seizures, asthma, or bulimia
-lowers seizure threshold
5. Lithium -gold standard for Bipolar
-therapeutic level 0.8-1.2
-early tox: 1.5-2.0
-advanced tox: 2.0-2.5
-severe tox: >2.5
-onset in 10-21 days
-hydration!!
-monitor sodium!
-kidney and thyroid levels!
-watch for N/V/D, fine hand tremors, thirst, polyuria
6. Anticonvulsant Mood Stabiliz- BIPOLAR
ers VALPROATE
-50-120 mcg/mL
-watch for liver toxicity