Disclaimer: This guide is a comprehensive study aid based on a projected syllabus.
Always refer to your official course materials, lectures, and textbooks as the primary
source for your exam preparation.
Section 1: Complex Health Alterations and Management
1. A patient with Acute Respiratory Distress Syndrome (ARDS) is on a mechanical
ventilator. The settings include low tidal volume (6 mL/kg ideal body weight) and
positive end-expiratory pressure (PEEP). What is the primary rationale for using
low tidal volume ventilation in this patient?
ANSWER ✓ To minimize ventilator-induced lung injury (VILI) by reducing volutrauma
and barotrauma to the alveoli.
2. A nurse is caring for a patient in septic shock. The physician orders intravenous
vasopressin to be added to the current norepinephrine infusion. What is the
primary therapeutic goal of adding vasopressin in this scenario?
ANSWER ✓ To synergistically increase systemic vascular resistance and mean arterial
pressure, often allowing for a reduction in the dose of catecholamine vasopressors like
norepinephrine.
3. During the management of a patient with a traumatic brain injury (TBI), the
nurse notes a sudden increase in intracranial pressure (ICP). Which three
interventions are part of the first-line, standard medical management for elevated
ICP?
ANSWER ✓ 1. Ensuring adequate sedation and analgesia. 2. Administering hyperosmolar
therapy (e.g., Mannitol or 3% Hypertonic Saline). 3. Maintaining the head of the bed
elevated to 30 degrees and ensuring proper head alignment to facilitate venous
drainage.
4. A patient with chronic heart failure presents with worsening dyspnea,
orthopnea, and jugular venous distension. The nurse administers intravenous
, furosemide. What is the primary intended physiological effect of this medication
in acute decompensated heart failure?
ANSWER ✓ To promote diuresis, which reduces preload by decreasing circulating blood
volume, thereby relieving pulmonary congestion and peripheral edema.
5. What is the key pathophysiological difference between Cardiogenic Shock and
Septic Shock?
ANSWER ✓ Cardiogenic shock is primarily caused by pump failure, leading to low
cardiac output and high systemic vascular resistance. Septic shock is primarily caused by
systemic vasodilation and capillary leak, leading to low systemic vascular resistance and
a compensatory high cardiac output in the early stages.
6. A patient with Diabetic Ketoacidosis (DKA) has an initial potassium level of 5.5
mEq/L. Why is it critical to initiate potassium replacement once the serum level
falls below 5.3 mEq/L, even though the initial level appears normal or high?
ANSWER ✓ Because the initial hyperkalemia is misleading and is caused by a shift of
potassium from the intracellular to extracellular space due to acidosis and insulin
deficiency. Once insulin therapy and fluid resuscitation are started, potassium will shift
back into the cells, rapidly causing profound hypokalemia, which can lead to fatal
cardiac dysrhythmias.
7. The nurse is preparing to administer tissue plasminogen activator (tPA) to a
patient with an acute ischemic stroke. What is the most critical screening factor
the nurse must verify before administration?
ANSWER ✓ The exact time of symptom onset must be within the approved therapeutic
window (typically 3-4.5 hours) to avoid the high risk of hemorrhagic conversion in
patients outside this window.
8. In the management of a patient with a massive Pulmonary Embolism (PE), what
is the primary indication for the use of thrombolytic therapy?
ANSWER ✓ The presence of hemodynamic instability (e.g., hypotension, cardiogenic
shock).
9. A patient with liver cirrhosis develops Hepatic Encephalopathy. The nurse would
expect to administer which medication to help reduce ammonia levels?
, ANSWER ✓ Lactulose, which works by acidifying the colon, trapping ammonium ions
(NH4+), and promoting its excretion in the stool.
10. What is the primary mechanism of action of Beta-blockers in the management
of chronic heart failure with reduced ejection fraction (HFrEF)?
ANSWER ✓ They block the harmful effects of chronic sympathetic nervous system
activation (e.g., tachycardia, increased myocardial oxygen demand, and remodeling),
leading to improved left ventricular function over time.
11. A patient with myasthenia gravis is admitted with an acute exacerbation. The
nurse should be prepared for which life-threatening complication?
ANSWER ✓ Myasthenic crisis, characterized by severe muscle weakness leading to acute
respiratory failure from diaphragmatic and intercostal muscle involvement.
12. When managing a patient with Severe Sepsis, what is the goal for the initial
fluid resuscitation within the first 3 hours?
ANSWER ✓ To administer 30 mL/kg of crystalloid fluid.
13. A patient with Addisonian Crisis (acute adrenal insufficiency) will present with
what key laboratory finding?
ANSWER ✓ Hyponatremia and hyperkalemia.
14. What is the primary reason a patient with Guillain-Barré Syndrome (GBS)
requires continuous monitoring in an ICU?
ANSWER ✓ To detect and manage ascending paralysis that can lead to acute respiratory
failure and autonomic dysfunction.
15. The nurse is caring for a patient with a thyroid storm. Which medication is
considered a first-line treatment to inhibit the release of pre-formed thyroid
hormone?
ANSWER ✓ Potassium Iodide (SSKI).
16. In a patient with acute pancreatitis, what two laboratory values are most
commonly elevated?
ANSWER ✓ Serum amylase and lipase (with lipase being more specific).