NURS 3335 EXAM SCRIPT 2025/2026 QUESTIONS AND
SOLUTION RATED A+
✔✔What is the MOA of Spironolactone? - ✔✔Blocks aldosterone in distal tubules,
leading to Na and H2O excretion and K+ retention
✔✔What are side effects of Spironolactone? - ✔✔Hyperkalemia, gynecomastia,
amenorrhea, dizziness, tumors
✔✔What are nursing considerations for Spironolactone? - ✔✔Avoid potassium-rich
foods, monitor for hyperkalemia, give in morning
✔✔What is potassium used for? - ✔✔To treat or prevent hypokalemia, treat digoxin
toxicity, prevent arrhythmias
✔✔What are nursing considerations for IV potassium? - ✔✔Never give IV push, max 10
mEq/hr (med-surg), monitor renal function and serum K+
✔✔What are therapeutic uses of Magnesium? - ✔✔Treat hypomagnesemia,
preeclampsia, preterm labor (tocolytic)
✔✔What are side effects of IV magnesium? - ✔✔Flushing, hypotension, bradycardia,
decreased DTRs, respiratory depression
✔✔What are nursing considerations for Magnesium? - ✔✔Monitor Mg levels (1.5-2.5),
DTRs, respirations; keep calcium gluconate nearby
✔✔What drug class is Duloxetine? - ✔✔SSNRI (Serotonin-Norepinephrine Reuptake
Inhibitor)
✔✔What is Duloxetine used for? - ✔✔Major depressive disorder, generalized anxiety
disorder, social anxiety, neuropathic pain
✔✔What is the MOA of Duloxetine? - ✔✔Inhibits reuptake of serotonin and
norepinephrine, increasing their availability in the brain
✔✔What are side effects of Duloxetine? - ✔✔Nervousness, agitation, dry mouth,
headache, insomnia, GI upset, erectile dysfunction
✔✔What are nursing considerations for Duloxetine? - ✔✔Monitor for suicidal thoughts,
serotonin syndrome, avoid alcohol and grapefruit juice, do not stop abruptly
✔✔What drug class is Fluoxetine? - ✔✔SSRI (Selective Serotonin Reuptake Inhibitor)
, ✔✔What is Fluoxetine used for? - ✔✔Major depression, OCD, PTSD, panic disorder,
migraines
✔✔What is the MOA of Fluoxetine? - ✔✔Inhibits serotonin reuptake, increasing
serotonin in the brain
✔✔What are side effects of Fluoxetine? - ✔✔Nervousness, dry mouth, insomnia, GI
upset, sexual dysfunction, weight gain
✔✔What are nursing considerations for Fluoxetine? - ✔✔Monitor for suicidal thoughts,
serotonin syndrome, avoid grapefruit juice, takes 2-4 weeks for full effect
✔✔What drug class is Amitriptyline? - ✔✔Tricyclic Antidepressant (TCA)
✔✔What is Amitriptyline used for? - ✔✔Major depression, OCD, insomnia, fibromyalgia,
migraines, neuropathy
✔✔What is the MOA of Amitriptyline? - ✔✔Inhibits reuptake of serotonin and
norepinephrine; also blocks alpha, histamine, and muscarinic receptors
✔✔What are side effects of Amitriptyline? - ✔✔Orthostatic hypotension, sedation,
anticholinergic effects, weight gain, cardiotoxicity
✔✔What are nursing considerations for Amitriptyline? - ✔✔Monitor for suicidal thoughts,
do not stop abruptly, teach about anticholinergic side effects
✔✔What is a key risk of MAOIs? - ✔✔Hypertensive crisis from tyramine-rich foods
✔✔What are MAOIs used for? - ✔✔Depression resistant to TCAs or SSRIs, Parkinson's
disease
✔✔What are nursing considerations for MAOIs? - ✔✔Avoid aged cheese, wine,
chocolate, caffeine, and OTC cold meds; monitor for serotonin syndrome and suicidal
thoughts
✔✔What drug class is Risperidone? - ✔✔Atypical (2nd Gen) Antipsychotic
✔✔What is Risperidone used for? - ✔✔Schizophrenia, bipolar disorder, psychosis, OCD
✔✔What is the MOA of Risperidone? - ✔✔Blocks serotonin and dopamine receptors to
balance neurotransmission
✔✔What are side effects of Risperidone? - ✔✔Weight gain, metabolic syndrome,
sedation, anticholinergic effects, EPS (rare), diabetes
SOLUTION RATED A+
✔✔What is the MOA of Spironolactone? - ✔✔Blocks aldosterone in distal tubules,
leading to Na and H2O excretion and K+ retention
✔✔What are side effects of Spironolactone? - ✔✔Hyperkalemia, gynecomastia,
amenorrhea, dizziness, tumors
✔✔What are nursing considerations for Spironolactone? - ✔✔Avoid potassium-rich
foods, monitor for hyperkalemia, give in morning
✔✔What is potassium used for? - ✔✔To treat or prevent hypokalemia, treat digoxin
toxicity, prevent arrhythmias
✔✔What are nursing considerations for IV potassium? - ✔✔Never give IV push, max 10
mEq/hr (med-surg), monitor renal function and serum K+
✔✔What are therapeutic uses of Magnesium? - ✔✔Treat hypomagnesemia,
preeclampsia, preterm labor (tocolytic)
✔✔What are side effects of IV magnesium? - ✔✔Flushing, hypotension, bradycardia,
decreased DTRs, respiratory depression
✔✔What are nursing considerations for Magnesium? - ✔✔Monitor Mg levels (1.5-2.5),
DTRs, respirations; keep calcium gluconate nearby
✔✔What drug class is Duloxetine? - ✔✔SSNRI (Serotonin-Norepinephrine Reuptake
Inhibitor)
✔✔What is Duloxetine used for? - ✔✔Major depressive disorder, generalized anxiety
disorder, social anxiety, neuropathic pain
✔✔What is the MOA of Duloxetine? - ✔✔Inhibits reuptake of serotonin and
norepinephrine, increasing their availability in the brain
✔✔What are side effects of Duloxetine? - ✔✔Nervousness, agitation, dry mouth,
headache, insomnia, GI upset, erectile dysfunction
✔✔What are nursing considerations for Duloxetine? - ✔✔Monitor for suicidal thoughts,
serotonin syndrome, avoid alcohol and grapefruit juice, do not stop abruptly
✔✔What drug class is Fluoxetine? - ✔✔SSRI (Selective Serotonin Reuptake Inhibitor)
, ✔✔What is Fluoxetine used for? - ✔✔Major depression, OCD, PTSD, panic disorder,
migraines
✔✔What is the MOA of Fluoxetine? - ✔✔Inhibits serotonin reuptake, increasing
serotonin in the brain
✔✔What are side effects of Fluoxetine? - ✔✔Nervousness, dry mouth, insomnia, GI
upset, sexual dysfunction, weight gain
✔✔What are nursing considerations for Fluoxetine? - ✔✔Monitor for suicidal thoughts,
serotonin syndrome, avoid grapefruit juice, takes 2-4 weeks for full effect
✔✔What drug class is Amitriptyline? - ✔✔Tricyclic Antidepressant (TCA)
✔✔What is Amitriptyline used for? - ✔✔Major depression, OCD, insomnia, fibromyalgia,
migraines, neuropathy
✔✔What is the MOA of Amitriptyline? - ✔✔Inhibits reuptake of serotonin and
norepinephrine; also blocks alpha, histamine, and muscarinic receptors
✔✔What are side effects of Amitriptyline? - ✔✔Orthostatic hypotension, sedation,
anticholinergic effects, weight gain, cardiotoxicity
✔✔What are nursing considerations for Amitriptyline? - ✔✔Monitor for suicidal thoughts,
do not stop abruptly, teach about anticholinergic side effects
✔✔What is a key risk of MAOIs? - ✔✔Hypertensive crisis from tyramine-rich foods
✔✔What are MAOIs used for? - ✔✔Depression resistant to TCAs or SSRIs, Parkinson's
disease
✔✔What are nursing considerations for MAOIs? - ✔✔Avoid aged cheese, wine,
chocolate, caffeine, and OTC cold meds; monitor for serotonin syndrome and suicidal
thoughts
✔✔What drug class is Risperidone? - ✔✔Atypical (2nd Gen) Antipsychotic
✔✔What is Risperidone used for? - ✔✔Schizophrenia, bipolar disorder, psychosis, OCD
✔✔What is the MOA of Risperidone? - ✔✔Blocks serotonin and dopamine receptors to
balance neurotransmission
✔✔What are side effects of Risperidone? - ✔✔Weight gain, metabolic syndrome,
sedation, anticholinergic effects, EPS (rare), diabetes
