Oregon MPJE Exam questions and
Answers 2025/2026
What is the law for selling a controlled substance for office use? CII? CIII-V? -
ANSWER-A prescription cannot be written to provide medical offices medications. If the
office wants CII medications a DEA 222 form must be used to transfer the CII stock. For
all other medications, an invoice must be utilized.
Does post-dating the prescription for a CII by the prescriber void the prescription? -
ANSWER-The prescription must have the date it was written on the hard copy. For
more information call the DEA office at 503-721-6660.
Is a typed CII prescription with an electronically signed signature a valid prescription? -
ANSWER-No. The prescription needs to be hand signed by the prescriber.
Is a CII perpetual inventory required in all practice settings? - ANSWER-No, it has been
required in hospitals for a long time (monthly reconciliation). A quarterly reconciliation is
required for retail pharmacies but not a perpetual inventory.
Is a pharmacist's signature required on hardcopies or will initials suffice? - ANSWER-It
is acceptable to either sign, initial, or utilize an electronic record identifying the verifying
pharmacist.
What information must be documented on the original hardcopy or electronic record (a
single screen) each time you partial fill a CII for hospice/terminally ill patients, long term
care or community based care patients? - ANSWER-The date dispensed, quantity
dispensed each time, amount remaining after each fill and pharmacist who dispensed it.
Can a CII prescription be changed from a capsule to a tablet or liquid form of the same
medication? - ANSWER-Yes, if you contact the prescriber and they authorize the
change. If the prescriber is not reasonably available for consultation and the prescribed
drug does not utilize a unique delivery system technoloy, an oral tablet, capsule or liquid
form of the prescribed drug so long as the form dispensed or administered has the
same strength, dose and dose schedule, and is therapuetically equivalent to the drug
prescribed. Per
If a CII medication is written with only the first or last name of patient, can a pharmacist
call the prescriber to clarify it and then fill the prescription? - ANSWER-Yes.
What changes can a pharmacist make to a CII prescription after speaking to the
prescriber over the phone? - ANSWER-A pharmacist CAN change the drug strength,
dosage form, drug quantity, and the directions. Changes that cannot be made are the
patient's name, controlled substance prescribed, and the addition of a prescriber's
signature (the prescription must be hand signed).
,Can a pharmacist change the date-to-fill after talking to the prescribing doctor on a CII?
- ANSWER-The date-to-fill is part of the directions written on the script therefore it would
be allowed to change after speaking with the prescribing doctor.
How are outdated CIIs destroyed? - ANSWER-See 21 CFR 1307.21and OAR 855-080-
0105 (reverse distributor, DEA, Board approved Plan).
Can physician assistants and naturopaths prescribe CII medications? - ANSWER-Yes,
check the formulary at http://www.oregon.gov/OBNE/rules/850-060-0226.pdf. PAs may
if they hold a current DEA registration for CII medication.
Does a pharmacist need to cancel a CII prescription across its face and sign? -
ANSWER-No
Does the CII annual inventory have to be separated from the CIII-V inventory? -
ANSWER-Yes, they can be on the same report as long as listed out separately.
How long do we need to keep CII inventory records? - ANSWER-3 years.
What is required of drug outlets electronically ordering CIIs? - ANSWER-The
pharmacist must be able to retrieve the electronic DEA 222 from their ordering system
for review by Board inspectors. This electronic form must contain the date and quantity
of each controlled substance received.
In which cases are partial fills on CII prescriptions allowed? - ANSWER-Partial fills are
allowed on CII prescriptions when: 1)The pharmacist is unable to fill the entire amount
and the remaining balance is dispensed within 72 hours. If the remainder is not filled
within that timeframe, then the remainder is lost and the prescriber should be notified of
the actual quantity filled. 2)For patients that are residing in a long term care facility or
community based care facility or diagnosed with a terminal illness in which scripts are
good for 60 days from the date the prescription was written.
In which situations can a faxed CII prescription serve as an original prescription? -
ANSWER-A faxed prescription can serve as an original for patients in a long term care
facility , community based care, enrolled in hospice, or receiving home infusion/IV pain
management therapy. The prescription must be manually signed by the prescriber prior
to faxing.
Is it legal to write/fill a CII prescription on the same page as a second prescription? -
ANSWER-Yes, but the prescriptions must be correctly filed and cross-referenced. The
original must be filed under the highest controlled prescription.
If a prescriber writes for a quantity of a CII that is greater than the amount the patient's
insurance will pay for, can the prescription be split into two prescriptions, one for
, insurance and one for cash? - ANSWER-Yes. Both prescriptions must be filled and
dispensed/sold at the same time.
Can a prescriber write multiple prescriptions for a CII on the same day to be filled on
different dates? - ANSWER-Yes, as long as the total quantity does not exceed a 90 day
supply and each subsequent prescription states the earliest date it can be filled and the
practitioner provides written instructions on each written prescription. [CFR
1306.12(b((ii)]
Can prescribers post date CII prescriptions? - ANSWER-No, the prescription must have
the date that the prescription is actually written and a fill date can be designated in the
instructions to the pharmacist.
Does a limit exist on the quantity of CII medication that can be dispensed from a single
prescription? - ANSWER-No, but use professional judgment.
Is it ok to fill a CII from a state that is not contiguous? - ANSWER-Yes, but use
professional judgement and make certain the prescription is valid. ORS 689.525(1)(2)
For drug recalls on a CII, can good drug be exchanged for the recalled drug? -
ANSWER-Yes, it can be exchanged without a new prescription, but you need to
document on the hardcopy what was taken back and the quantity replaced.
If there is a shortage of a CII such as oxycodone, can the RPh change the drug to
oxycodone/APAP after consulting the practitioner? - ANSWER-Yes.
Can a CII be transferred between pharmacies with interactive databases (i.e..
Walgreen's)? - ANSWER-Under no circumstance can a CII be transferred.
Do you have to file CIII-V invoices separate from CII invoices? - ANSWER-Yes.
Is it ok if CIII-V prescriptions are filed with regular legend drugs even if there is no
identifier to manually separate them? - ANSWER-Yes, as long as the store can run a
report of all CIII-Vs dispensed that is separate from the regular legend drugs.
How many refills are allowed by law on schedule III-V medications? - ANSWER-A
prescription written for a schedule III-V medication is good for 6 months or 5 refills
whichever comes first.
Can a prescriber's agent call in or verbally verify a CIII-V prescription? - ANSWER-Yes,
they can verbally verify it for the pharmacist or intern.
Can a pharmacy fill an e-script for a scheduled III-V medication? - ANSWER-Yes, If in
compliance with CFR 1306.08.
Answers 2025/2026
What is the law for selling a controlled substance for office use? CII? CIII-V? -
ANSWER-A prescription cannot be written to provide medical offices medications. If the
office wants CII medications a DEA 222 form must be used to transfer the CII stock. For
all other medications, an invoice must be utilized.
Does post-dating the prescription for a CII by the prescriber void the prescription? -
ANSWER-The prescription must have the date it was written on the hard copy. For
more information call the DEA office at 503-721-6660.
Is a typed CII prescription with an electronically signed signature a valid prescription? -
ANSWER-No. The prescription needs to be hand signed by the prescriber.
Is a CII perpetual inventory required in all practice settings? - ANSWER-No, it has been
required in hospitals for a long time (monthly reconciliation). A quarterly reconciliation is
required for retail pharmacies but not a perpetual inventory.
Is a pharmacist's signature required on hardcopies or will initials suffice? - ANSWER-It
is acceptable to either sign, initial, or utilize an electronic record identifying the verifying
pharmacist.
What information must be documented on the original hardcopy or electronic record (a
single screen) each time you partial fill a CII for hospice/terminally ill patients, long term
care or community based care patients? - ANSWER-The date dispensed, quantity
dispensed each time, amount remaining after each fill and pharmacist who dispensed it.
Can a CII prescription be changed from a capsule to a tablet or liquid form of the same
medication? - ANSWER-Yes, if you contact the prescriber and they authorize the
change. If the prescriber is not reasonably available for consultation and the prescribed
drug does not utilize a unique delivery system technoloy, an oral tablet, capsule or liquid
form of the prescribed drug so long as the form dispensed or administered has the
same strength, dose and dose schedule, and is therapuetically equivalent to the drug
prescribed. Per
If a CII medication is written with only the first or last name of patient, can a pharmacist
call the prescriber to clarify it and then fill the prescription? - ANSWER-Yes.
What changes can a pharmacist make to a CII prescription after speaking to the
prescriber over the phone? - ANSWER-A pharmacist CAN change the drug strength,
dosage form, drug quantity, and the directions. Changes that cannot be made are the
patient's name, controlled substance prescribed, and the addition of a prescriber's
signature (the prescription must be hand signed).
,Can a pharmacist change the date-to-fill after talking to the prescribing doctor on a CII?
- ANSWER-The date-to-fill is part of the directions written on the script therefore it would
be allowed to change after speaking with the prescribing doctor.
How are outdated CIIs destroyed? - ANSWER-See 21 CFR 1307.21and OAR 855-080-
0105 (reverse distributor, DEA, Board approved Plan).
Can physician assistants and naturopaths prescribe CII medications? - ANSWER-Yes,
check the formulary at http://www.oregon.gov/OBNE/rules/850-060-0226.pdf. PAs may
if they hold a current DEA registration for CII medication.
Does a pharmacist need to cancel a CII prescription across its face and sign? -
ANSWER-No
Does the CII annual inventory have to be separated from the CIII-V inventory? -
ANSWER-Yes, they can be on the same report as long as listed out separately.
How long do we need to keep CII inventory records? - ANSWER-3 years.
What is required of drug outlets electronically ordering CIIs? - ANSWER-The
pharmacist must be able to retrieve the electronic DEA 222 from their ordering system
for review by Board inspectors. This electronic form must contain the date and quantity
of each controlled substance received.
In which cases are partial fills on CII prescriptions allowed? - ANSWER-Partial fills are
allowed on CII prescriptions when: 1)The pharmacist is unable to fill the entire amount
and the remaining balance is dispensed within 72 hours. If the remainder is not filled
within that timeframe, then the remainder is lost and the prescriber should be notified of
the actual quantity filled. 2)For patients that are residing in a long term care facility or
community based care facility or diagnosed with a terminal illness in which scripts are
good for 60 days from the date the prescription was written.
In which situations can a faxed CII prescription serve as an original prescription? -
ANSWER-A faxed prescription can serve as an original for patients in a long term care
facility , community based care, enrolled in hospice, or receiving home infusion/IV pain
management therapy. The prescription must be manually signed by the prescriber prior
to faxing.
Is it legal to write/fill a CII prescription on the same page as a second prescription? -
ANSWER-Yes, but the prescriptions must be correctly filed and cross-referenced. The
original must be filed under the highest controlled prescription.
If a prescriber writes for a quantity of a CII that is greater than the amount the patient's
insurance will pay for, can the prescription be split into two prescriptions, one for
, insurance and one for cash? - ANSWER-Yes. Both prescriptions must be filled and
dispensed/sold at the same time.
Can a prescriber write multiple prescriptions for a CII on the same day to be filled on
different dates? - ANSWER-Yes, as long as the total quantity does not exceed a 90 day
supply and each subsequent prescription states the earliest date it can be filled and the
practitioner provides written instructions on each written prescription. [CFR
1306.12(b((ii)]
Can prescribers post date CII prescriptions? - ANSWER-No, the prescription must have
the date that the prescription is actually written and a fill date can be designated in the
instructions to the pharmacist.
Does a limit exist on the quantity of CII medication that can be dispensed from a single
prescription? - ANSWER-No, but use professional judgment.
Is it ok to fill a CII from a state that is not contiguous? - ANSWER-Yes, but use
professional judgement and make certain the prescription is valid. ORS 689.525(1)(2)
For drug recalls on a CII, can good drug be exchanged for the recalled drug? -
ANSWER-Yes, it can be exchanged without a new prescription, but you need to
document on the hardcopy what was taken back and the quantity replaced.
If there is a shortage of a CII such as oxycodone, can the RPh change the drug to
oxycodone/APAP after consulting the practitioner? - ANSWER-Yes.
Can a CII be transferred between pharmacies with interactive databases (i.e..
Walgreen's)? - ANSWER-Under no circumstance can a CII be transferred.
Do you have to file CIII-V invoices separate from CII invoices? - ANSWER-Yes.
Is it ok if CIII-V prescriptions are filed with regular legend drugs even if there is no
identifier to manually separate them? - ANSWER-Yes, as long as the store can run a
report of all CIII-Vs dispensed that is separate from the regular legend drugs.
How many refills are allowed by law on schedule III-V medications? - ANSWER-A
prescription written for a schedule III-V medication is good for 6 months or 5 refills
whichever comes first.
Can a prescriber's agent call in or verbally verify a CIII-V prescription? - ANSWER-Yes,
they can verbally verify it for the pharmacist or intern.
Can a pharmacy fill an e-script for a scheduled III-V medication? - ANSWER-Yes, If in
compliance with CFR 1306.08.
