FPGEE TEST PAPER 2025/2026 QUESTIONS AND SOLUTION
RATED A+
✔✔Gravimetric methods - ✔✔Weighing drugs after separation
Weighing a derivative after separation
Weighing residue after ignition
✔✔Spectrometric methods - ✔✔Colorimetric
UV, IR, NMR, Atomic absorption
Fluorimetric emission
✔✔Electrochemical methods - ✔✔Voltammetery
Potentiometery
✔✔Chromatographic - ✔✔TLC, HPLC,Gas chromatography
✔✔Abnormal hemoglobin, hemolytic anemia - ✔✔Sickle cell anemia, beta- thalassemia
✔✔How abnormal hemoglobin could cause rupture of red blood cells - ✔✔It's solubility
is low and make crystal
✔✔What is the problem in patients with less G6PD enzyme - ✔✔G6PD CAuse
hemoglobin donot oxidase when it's less it leads to hemolytic so when patient get
oxidant drugs
✔✔Oxidant drugs cause problems in G6PD deficiency - ✔✔Primaquine, sulfonamide,
nitrofuran, nalidixic acid,probenecid, chloroquine , dimercaptol
✔✔PKU - ✔✔phenylketonuria , increase phenylalanine level in blood, increase
phenylpyruvic acid in urine, cause mental deficiency, Guthrie test is for detection
✔✔Metabolic product of epinephrine and norepinephrine - ✔✔Vanillymandelic acid
✔✔Metabolic product of dopamine - ✔✔Homovanillic acid
✔✔Metabolic product of serotonin - ✔✔5 hydroxyindoleacetic acid
✔✔Anaerobic MO - ✔✔clostridium
Corynebacterium diphtheria
✔✔Urticaria or hives - ✔✔Wheat, intense pruritus or burning
✔✔Eczema or atopic dermatitis - ✔✔Itching, infant, childhood, adult type
, ✔✔Allergic contact dermatitis - ✔✔Soap
✔✔Exfoliative dermatitis - ✔✔Fatal due to other poorly controlled dermatitis
✔✔Erythema multiform - ✔✔Systemic allergic reaction
Stevens Johnson syndrom
✔✔Impetigo - ✔✔Bacterial, common in children, staphylococci and streptococci
✔✔Zero order reaction - ✔✔R=k, unit k=mg/s
A=-kt+A0,
t1/2=A0/2k
✔✔First order reaction - ✔✔R=k[A] unit k= 1/s
LnA= -kt+lnA0
K= 2.303/t log (A0/[A])
t1/2= 0.693/k
✔✔Second order reaction - ✔✔R=k[A]^2
1/[A]= kt+1/[A0]
T1/2=1/kA0
✔✔6 condition decrease albumin level have risk of toxixity - ✔✔Chronic liver disease
Chronic renal failure
Pregnancy
Burns
Trauma
Cystic fibrosis
✔✔One disease that increase albumin level and the drug would be less effective -
✔✔Hypothyroidism
✔✔Cimetidine - ✔✔GERD, Heartburn
Cp450 inhibitor
Diarrhea , headache , pancreatitis
400 mg bid
✔✔Hyper ammonia - ✔✔Lactulose, it is degraded into acid and entrapment the
ammonium ion in the colon
✔✔Hemophilia - ✔✔Deficiency coagulation factor 8 known as anti hemophiliac
factor(AHF)
Indication hemorrhage in hemophilia
Prevent bleeding I surgical procedure
RATED A+
✔✔Gravimetric methods - ✔✔Weighing drugs after separation
Weighing a derivative after separation
Weighing residue after ignition
✔✔Spectrometric methods - ✔✔Colorimetric
UV, IR, NMR, Atomic absorption
Fluorimetric emission
✔✔Electrochemical methods - ✔✔Voltammetery
Potentiometery
✔✔Chromatographic - ✔✔TLC, HPLC,Gas chromatography
✔✔Abnormal hemoglobin, hemolytic anemia - ✔✔Sickle cell anemia, beta- thalassemia
✔✔How abnormal hemoglobin could cause rupture of red blood cells - ✔✔It's solubility
is low and make crystal
✔✔What is the problem in patients with less G6PD enzyme - ✔✔G6PD CAuse
hemoglobin donot oxidase when it's less it leads to hemolytic so when patient get
oxidant drugs
✔✔Oxidant drugs cause problems in G6PD deficiency - ✔✔Primaquine, sulfonamide,
nitrofuran, nalidixic acid,probenecid, chloroquine , dimercaptol
✔✔PKU - ✔✔phenylketonuria , increase phenylalanine level in blood, increase
phenylpyruvic acid in urine, cause mental deficiency, Guthrie test is for detection
✔✔Metabolic product of epinephrine and norepinephrine - ✔✔Vanillymandelic acid
✔✔Metabolic product of dopamine - ✔✔Homovanillic acid
✔✔Metabolic product of serotonin - ✔✔5 hydroxyindoleacetic acid
✔✔Anaerobic MO - ✔✔clostridium
Corynebacterium diphtheria
✔✔Urticaria or hives - ✔✔Wheat, intense pruritus or burning
✔✔Eczema or atopic dermatitis - ✔✔Itching, infant, childhood, adult type
, ✔✔Allergic contact dermatitis - ✔✔Soap
✔✔Exfoliative dermatitis - ✔✔Fatal due to other poorly controlled dermatitis
✔✔Erythema multiform - ✔✔Systemic allergic reaction
Stevens Johnson syndrom
✔✔Impetigo - ✔✔Bacterial, common in children, staphylococci and streptococci
✔✔Zero order reaction - ✔✔R=k, unit k=mg/s
A=-kt+A0,
t1/2=A0/2k
✔✔First order reaction - ✔✔R=k[A] unit k= 1/s
LnA= -kt+lnA0
K= 2.303/t log (A0/[A])
t1/2= 0.693/k
✔✔Second order reaction - ✔✔R=k[A]^2
1/[A]= kt+1/[A0]
T1/2=1/kA0
✔✔6 condition decrease albumin level have risk of toxixity - ✔✔Chronic liver disease
Chronic renal failure
Pregnancy
Burns
Trauma
Cystic fibrosis
✔✔One disease that increase albumin level and the drug would be less effective -
✔✔Hypothyroidism
✔✔Cimetidine - ✔✔GERD, Heartburn
Cp450 inhibitor
Diarrhea , headache , pancreatitis
400 mg bid
✔✔Hyper ammonia - ✔✔Lactulose, it is degraded into acid and entrapment the
ammonium ion in the colon
✔✔Hemophilia - ✔✔Deficiency coagulation factor 8 known as anti hemophiliac
factor(AHF)
Indication hemorrhage in hemophilia
Prevent bleeding I surgical procedure
