UWSA 2 100% EXAM QUESTIONS AND ANSWERS VERIFIED 100% CORRECT

UWSA 2 100% EXAM QUESTIONS AND ANSWERS VERIFIED 100% CORRECT Where are immunoglobulin deposits in pemphigus vulgaris? - ANSWER Between keratinocytes--> anti-desmosomes which form desmosomal junctions Deposits of IgG autoantibodies against the BM - ANSWER Bullous pemphigoid A lesion where causes Horner's syndrome? - ANSWER Cervical chain ganglion Ciliary ganglion - ANSWER Controls CN III Patient with a long history of alcohol abuse comes to the ED due to frequent falls. He feels unsteady, has blurred vision, and has a course postural tremor. Where is the lesion? - ANSWER Cerebellum Alcoholic cerebellar degeneration--> most prominent in the cerebellar vermis. Defect with nephrogenic diabetes insipidus - ANSWER Dysfunction of the collecting tubules Impaired ADH production - ANSWER Central DI Psychogenic polydipsia - ANSWER Urine specific gravity will rise appropriately is response to fluid restriction Anemia due to brisk and painless lower GI bleeding - ANSWER Meckel's diverticulum (heterotopic mucosa) Failed obliteration of the omphalomesenteric duct - ANSWER Meckel's diverticulum Bilious emesis, abdominal pain, and bloody stools - ANSWER Volvulus--> bowel may rotate incompletely round the SMA Severe intermittent abdominal pain, vomiting, bloody stools, and palpable abdominal mass - ANSWER Intussusception Finding in HCM - ANSWER Thickened IV septum Normal coronary arteries Disordered arrangement of cardiac myofibrils AS murmur that increases with standing A widely split heart sound is heard at the upper sternal border that is accentuated with inspiration. Where will it be heart on the curve? - ANSWER When the aortic valve closes A wide split S2 can occur with delayed closure of the pulmonic valve--> RBBB, pulmonic stenosis, and P HTN. Heard with the closure of the AV. When is a BAV heard? - ANSWER When aortic valve opens Where is MS heard? - ANSWER When MV opens What is needed for removal and replacement of primers with DNA? - ANSWER DNA Pol I DNA Pol I - ANSWER Removes RNA primer and replaces it with DNA DNA Pol III - ANSWER 5' to 3' DNA synthesis 3' to 5' exonuclease What do you want for a screening test? - ANSWER High sensitivity and low 1- specificity (false positives) HNPCC - ANSWER Mutation in mismatch repair gene Inactivation of nonhomologous end-joining repair - ANSWER Ataxia Telangiectasia Gain of function in RET gene - ANSWER MEN 2A/2B Medication after transplant that can cause obliterative vasculopathy of afferent arterioles - ANSWER Tacrolimus Causes a dose-dependent rise in BUN and creatinine What medication should you not give a patient with Parkinsons? - ANSWER Metoclopramide What is the complication of alkaptonuria? - ANSWER Osteoarthropathy Def in homgentisic acid dioxygenase Blackening of urine Increased resistance to passive elbow flexion and extension and a hand tremor that disappears with movement - ANSWER PD A patient with Afib has a cold and pale right foot without a palpable pulse over the dorsalis pedis artery. What will be increased in the extracellular space? - ANSWER K+ Na+/K+ pump won't work--> increased IC Na+ and Ca2+ and increased extracellular K+ Darkly staining cells in a glomerulus - ANSWER JGA cells--> produce renin A sample of amniotic fluid is added to a test well containing ethanol. The mixture is shaken and stable ring of foam appears. What substance? - ANSWER Surfactant--> composed of phospholipids What causes amenorrhea in anorexic patients/ - ANSWER Decreased hypothalamic GnRH secretion Patient with Marfan symptoms, dislocated lens, intellectual delay and history of sinus venous thrombosis - ANSWER CBS mutation--> homocystinuria Increased methionine and homocystien Pancreatic pseudocyst - ANSWER Collection of fluid with calcifications in the pancreas. Compresses the IVC What primers yield complementary copies of a DNA sequence during PCR? - ANSWER Have to be in 5' to 3' direction 3' end needs to be oriented toward target DNA Why is heparin safer than warfarin during pregnancy? - ANSWER Higher water solubility --> goes not cross the placenta What factor of Neiserria gonorrhea allows it to establish and STD? - ANSWER Pili--> allows it to bind to the host cell What is the MOA for the drug used to treat CMV retinitis? - ANSWER Blocks DNA proliferation--> ganciclovir What mutation is passed to viral progeny? - ANSWER Reassortme