BIOCHEMISTRY (PACOP Blue)
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1. What two enzymes are used to bypass the pyruvate kinase reaction of glycol-
ysis?
I. pyruvate carboxylase
II. PEP carboxykinase
III. Fructose biphosphatase
IV. Glucose-6-phosphate
A. I & II D. II & IV
B. III & IV E. II & III
C. I &III: A
2. Which of the following includes the main goals of Pentose Phosphate Path-
way?
I. produce ribose-5-phosphate for nucleotide synthesis
II. produce NADPH and NADP for oxidoreductive biochemical synthesis
III. to interconvert pentoses and hexoses
A. I & II D. I, II & III
B. II & III
C. I & III: D
3. Which of the following statements is/are true regarding the secondary struc-
ture of
nucleic acids?
I. Guanine forms base pairs with cytosine via 2 hydrogen bonds
II. The B form of the DNA is the most common in biological systems
III. The breaking of H-bonds caused by high temperature is called melting
A. I,II & III D. I & II
B. I & II E. II only
C. II & III: C
4. The phospholipid, phosphatidylinositol 4,5-biphosphate forms the potent
secondary
messengers inositol triphosphate & diacylglycerol via what enzyme?
A. Phospholipase A D. Phospholipase B
B. Phospholipase C
C. Phospholipase D: B
, BIOCHEMISTRY (PACOP Blue)
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5. Which of the following is not true regarding the four enzyme complexes of
the electron
transport chain?
A. Complex I is known as the NADH-CoQ Oxidoreductases
B. Complex II is known as Succinate-CoQ Oxidoreductases
C. Complex III is known as Cytochrome Oxidase
D. Complex IV is known as Cytochrome Oxidase: C
6. Glucose and mannose are epimers at:
A. Carbon 4 C. Carbon 3
B. Carbon 2 D. Carbon 5: B
7. One important endogenous molecule for synthetic biotransformation of
xenobiotics is
glucoronic acid. It is actually the most dominant conjugative biotransformation
pathway due to the
readily available source of glucose. It is produce from glucose via:
A. Oxidation at carbon 1 C. Oxidation at carbon 6
B. Oxidation at carbon 2 D. Oxidation at carbon 1 & 6: D
8. Which of the following is not true about protein structure determination?
A. NMR is the primary means of determining protein structure
B. Protein are difficult to crystallize, a disadvantage of x-ray crystallography
C. An advantage of the use of the NMR is that proteins analyzed are in their
natural state
D. Large and very complex proteins can only be analyzed by x-ray crystallogra-
phy: A
9. Tertiary structures of proteins are primarily stabilized by
I. H-bonds
II. Hydrophobic interactions
III. Ionic bonds
IV. Disulfide bonds
A. I & III D. I, II& IV
B. II & IV E. II, III & IV
C. I,III & IV: B
, BIOCHEMISTRY (PACOP Blue)
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10. In an uncompetitive inhibition of enzymatic action :
A. Inhibitor binds either to the free enzyme or the enzyme substrate complex
B. Lineweaver-Burk plots of the enzyme alone (control) & the enzyme + inhibitor
are
parallel to each other
C. The apparent Km is raised
D. The Vmax is unaffected: B
11. Which biomolecule is not considered a biopolymer?
A. Proteins D. Nucleic acids
B. Lipids E. Fat
C. Carbohydrates: B
12. It is regarded as the universal biological energy currency
A. Adenosine triphosphate C. Uncouplers
B. Guanosine triphosphate D. Calories: A
13. This is the final electron receptor of the electron transport chain
A. Complex I C. Complex V
B. Complex II D. Complex IV: ???
14. The most accepted hypothesis regarding oxidative phosphorylation is
A. Chemical coupling D. Lock and Key Theory
B. Conformational coupling E. Diffusion
C. Chemiostatic hypothesis: C
15. This is a quantitative study of the energy transformationsin the living cell
A. Bioenergetics C. Proteonomics
B. Thermodynamics D. Metabolomics: A
16. Which of the following hormones promotes rapid glycogenolysis in both liver
and muscle
A. ACTH C. Epinephrine
B. Glutemine D. Prolactin: C
17. Which vitamin can be used in the management of hyperlipidemia?
A. Thiamine C. Niacin
B. Riboflavin D. Panthotenic acid: C
, BIOCHEMISTRY (PACOP Blue)
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18. Bond between 2 amino acids
A. Glycosidic bond C. Peptide Bond
B. N-glycosyl linkage D. Hydrogen bond: C
19. Beta oxidation of fatty acids occurs in the
A. Cytosol C. Endoplasmic reticulum
B. Mitochondria D. Ribosomes: ???
20. The pentose phosphate pathway occur in the ________ of the liver, muscle and
kidney.
A. cytosol C. endoplasmic reticulum
B. mitochondria D. ribosomes: C
21. The isoelctric point is the
A. pH where the alpha amino acid exist in its negatively charged form
B. pH wherein the amino acid exist in zwitterionic form
C. Temperature at which the amino acid denatures
D. Pressure at which the amino acid hydrolyzes: B
22. This is the only optically inactive amino acid
A. methionine C. Citrulline
B. Lysine D. glycine: D
23. This level of protein structure is applicable only to those have several sub-
units
A. Primary C. Tertiary
B. Secondary D. Quaternary: D
24. Arginine is the only metabolite of the urea cycle that does not accumulate
because
A. It is readily excreted
B. It is used up by the body for protein synthesis
C. There is no known deficiency in the enzyme that catabolizes it
D. It can ve acquired from food: B
25. This is the genetic condition characterized by deficiency of the enzyme
branched chain
alpha-keto acid dehydrogenase
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1. What two enzymes are used to bypass the pyruvate kinase reaction of glycol-
ysis?
I. pyruvate carboxylase
II. PEP carboxykinase
III. Fructose biphosphatase
IV. Glucose-6-phosphate
A. I & II D. II & IV
B. III & IV E. II & III
C. I &III: A
2. Which of the following includes the main goals of Pentose Phosphate Path-
way?
I. produce ribose-5-phosphate for nucleotide synthesis
II. produce NADPH and NADP for oxidoreductive biochemical synthesis
III. to interconvert pentoses and hexoses
A. I & II D. I, II & III
B. II & III
C. I & III: D
3. Which of the following statements is/are true regarding the secondary struc-
ture of
nucleic acids?
I. Guanine forms base pairs with cytosine via 2 hydrogen bonds
II. The B form of the DNA is the most common in biological systems
III. The breaking of H-bonds caused by high temperature is called melting
A. I,II & III D. I & II
B. I & II E. II only
C. II & III: C
4. The phospholipid, phosphatidylinositol 4,5-biphosphate forms the potent
secondary
messengers inositol triphosphate & diacylglycerol via what enzyme?
A. Phospholipase A D. Phospholipase B
B. Phospholipase C
C. Phospholipase D: B
, BIOCHEMISTRY (PACOP Blue)
Study online at https://quizlet.com/_hwxptw
5. Which of the following is not true regarding the four enzyme complexes of
the electron
transport chain?
A. Complex I is known as the NADH-CoQ Oxidoreductases
B. Complex II is known as Succinate-CoQ Oxidoreductases
C. Complex III is known as Cytochrome Oxidase
D. Complex IV is known as Cytochrome Oxidase: C
6. Glucose and mannose are epimers at:
A. Carbon 4 C. Carbon 3
B. Carbon 2 D. Carbon 5: B
7. One important endogenous molecule for synthetic biotransformation of
xenobiotics is
glucoronic acid. It is actually the most dominant conjugative biotransformation
pathway due to the
readily available source of glucose. It is produce from glucose via:
A. Oxidation at carbon 1 C. Oxidation at carbon 6
B. Oxidation at carbon 2 D. Oxidation at carbon 1 & 6: D
8. Which of the following is not true about protein structure determination?
A. NMR is the primary means of determining protein structure
B. Protein are difficult to crystallize, a disadvantage of x-ray crystallography
C. An advantage of the use of the NMR is that proteins analyzed are in their
natural state
D. Large and very complex proteins can only be analyzed by x-ray crystallogra-
phy: A
9. Tertiary structures of proteins are primarily stabilized by
I. H-bonds
II. Hydrophobic interactions
III. Ionic bonds
IV. Disulfide bonds
A. I & III D. I, II& IV
B. II & IV E. II, III & IV
C. I,III & IV: B
, BIOCHEMISTRY (PACOP Blue)
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10. In an uncompetitive inhibition of enzymatic action :
A. Inhibitor binds either to the free enzyme or the enzyme substrate complex
B. Lineweaver-Burk plots of the enzyme alone (control) & the enzyme + inhibitor
are
parallel to each other
C. The apparent Km is raised
D. The Vmax is unaffected: B
11. Which biomolecule is not considered a biopolymer?
A. Proteins D. Nucleic acids
B. Lipids E. Fat
C. Carbohydrates: B
12. It is regarded as the universal biological energy currency
A. Adenosine triphosphate C. Uncouplers
B. Guanosine triphosphate D. Calories: A
13. This is the final electron receptor of the electron transport chain
A. Complex I C. Complex V
B. Complex II D. Complex IV: ???
14. The most accepted hypothesis regarding oxidative phosphorylation is
A. Chemical coupling D. Lock and Key Theory
B. Conformational coupling E. Diffusion
C. Chemiostatic hypothesis: C
15. This is a quantitative study of the energy transformationsin the living cell
A. Bioenergetics C. Proteonomics
B. Thermodynamics D. Metabolomics: A
16. Which of the following hormones promotes rapid glycogenolysis in both liver
and muscle
A. ACTH C. Epinephrine
B. Glutemine D. Prolactin: C
17. Which vitamin can be used in the management of hyperlipidemia?
A. Thiamine C. Niacin
B. Riboflavin D. Panthotenic acid: C
, BIOCHEMISTRY (PACOP Blue)
Study online at https://quizlet.com/_hwxptw
18. Bond between 2 amino acids
A. Glycosidic bond C. Peptide Bond
B. N-glycosyl linkage D. Hydrogen bond: C
19. Beta oxidation of fatty acids occurs in the
A. Cytosol C. Endoplasmic reticulum
B. Mitochondria D. Ribosomes: ???
20. The pentose phosphate pathway occur in the ________ of the liver, muscle and
kidney.
A. cytosol C. endoplasmic reticulum
B. mitochondria D. ribosomes: C
21. The isoelctric point is the
A. pH where the alpha amino acid exist in its negatively charged form
B. pH wherein the amino acid exist in zwitterionic form
C. Temperature at which the amino acid denatures
D. Pressure at which the amino acid hydrolyzes: B
22. This is the only optically inactive amino acid
A. methionine C. Citrulline
B. Lysine D. glycine: D
23. This level of protein structure is applicable only to those have several sub-
units
A. Primary C. Tertiary
B. Secondary D. Quaternary: D
24. Arginine is the only metabolite of the urea cycle that does not accumulate
because
A. It is readily excreted
B. It is used up by the body for protein synthesis
C. There is no known deficiency in the enzyme that catabolizes it
D. It can ve acquired from food: B
25. This is the genetic condition characterized by deficiency of the enzyme
branched chain
alpha-keto acid dehydrogenase
