Pharmacotherapeutics for Nurse Practitioner Prescribers, 3rd Edition

,Chapterr 1:r Ther Roler ofr ther Nurser Practitionerr asr Prescriber

MultiplerChoice
Identifyrtherchoicerthatrbestrcompletesrtherstatementrorranswersrtherquestion.
r
1. Nurserpractitionerr prescriptiver authorityr isrregulatedr by:
A. TherNationalr Councilr ofrStaterBoardsrofrNursing
B. TherU.S.rDrugr Enforcementr Administration
C. TherStaterBoardrofrNursingr forreachrstate
D. TherStaterBoardrofrPharmacy
r
2. Physicianr Assistantr (PA)rprescriptiver authorityr isrregulatedr by:
A. TherNationalr Councilr ofrStaterBoardsrofrNursing
B. TherU.S.rDrugr Enforcementr Administration
C. TherStaterBoardrofrNursing
D. TherStaterBoardrofrMedicalr Examiners
r
3. Clinicalr judgmentr inr prescribingr includes:
A. Factoringr inr thercostrtortherpatientr ofrthermedicationr prescribed
B. Alwaysr prescribingr thernewestr medicationr availabler forrtherdiseaserprocess
C.r Handingr outrdrugrsamplesrrtorpoorrpatients
D.r Prescribingr allr genericr medicationsr torcutrcosts
r
4. Criteriar forrchoosingr anreffectiver drugr forrardisorderrinclude:
A. Askingr therpatientr whatrdrugr theyrthinkr wouldr workrbestrforrthem
B. Consultingr nationallyr recognizedr guidelinesr forrdiseasermanagement
C. Prescribingr medicationsr thatrareravailabler asrsamplesr beforerwritingr arprescription
D. Followingr U.S.rDrugr Enforcementr Administrationr (DEA)rguidelinesr for
prescribing
r
5. Nurserpractitionerr practicer mayrthriver underrhealth-carer reformr duerto:
A. Therdemonstratedr abilityr ofrnurser practitionersr torcontrolr costsrandrimprover patientrout
comes
B. Therfactrthatrnurser practitionersr willr berablertorpracticerindependently
C. Therfactrthatrnurser practitionersr willr haver fullr reimbursementr underrhealth-care
reform
D.r Therabilityr torshiftr accountabilityr forrMedicaidr tortherstaterlevel

,Chapterr 1:r Ther Roler ofr ther Nurser Practitionerr asr PrescriberrAn
swerrSection

MULTIPLEr CHOICE

1. ANS:r C PTS:rr 1
2. ANS:r D PTS:rr 1
3. ANS:r A PTS:rr 1
4. ANS:r B PTS:rr 1
5. ANS:r A PTS:rr 1
Chapterr 2:r Reviewr ofr Basicr Principlesr ofr Pharmacology

MultiplerChoice
Identifyrtherchoicerthatrbestrcompletesrtherstatementrorranswersrtherquestion.
r
1. Arpatient’sr nutritionalr intaker andrlabrworkrreflectsr hypoalbuminemia.r Thisr isrcriticalr torpre
scribingr because:
A. Distributionr ofrdrugsrtortargetrtissuer mayrberaffected
B. Thersolubilityr ofrtherdrugr willr notrmatchr thersiterofrabsorption
C. Thererwillr berlessrfreerdrugr availabler torgenerater anreffect
D. Drugsr boundrtoralbuminr arerreadilyr excretedrbyrtherkidney
r
2. Drugsr thatrhaverarsignificantr first-passr effect:
A. Mustrbergivenr byrtherenteralr (oral)rrouteronly
B. Bypassrtherhepaticr circulation
C. Arerrapidlyr metabolizedr byrtherliverr andrmayrhaverlittler ifranyr desiredraction
D. Arerconvertedr byrtherliverr tormoreractiver andrfat-solubler forms
r
3. Therrouterofrexcretionr ofrarvolatiler drugrwillr likelyr be:
A. Therkidneys
B. Therlungs
C. Therbiler andrfeces
D. Therskin

r 4. Medroxyprogesteroner (DeporProvera)risrprescribedr IMrtorcreaterarstoragerreservoirr ofrthe
drug.rStoragerreservoirs:
A. Assurerthatrtherdrugrwillr reachritsrintendedr targetr tissue
B. Arertherreasonrforrgivingr loadingr doses
C. Increasertherlengthr ofrtimer ardrugrisravailabler andractive
D. Arermostrcommonr inr collagenr tissues
r
5. TherNPrchoosesrtorgiver cephalexinr everyr 8rhoursr basedronrknowledger ofrtherdrug’s:
A. Propensityr torgortorthertargetrreceptor
B. Biologicalr half-life
C. Pharmacodynamics
D. Safetyr andrsidereffects
r
6. Azithromycinr dosingr requiresr therfirstr day’srdoserbertwicerthoserofrtherotherr4rdaysrofrtherpres
cription.rThisr isrconsideredr arloadingr dose.rArloadingr dose:
A. Rapidlyr achievesr drugrlevelsr inr thertherapeuticr range
B. Requiresr fourr torfiver half-livesr torattain

, C.r Isrinfluencedr byrrenalr function
D.r Isrdirectlyr relatedr tortherdrugrcirculatingr torthertargetrtissues
r

7.r Therpointr inrtimer onrtherdrugrrconcentrationr curverthatrindicatesr therfirstr signr ofrartherapeuticre
ffectr isrthe:
A. Minimumr adversereffectr level
B. Peakrofraction
C. Onsetrofraction
D. Therapeuticr range

r 8.r Phenytoinr requiresr artroughr levelr berdrawn.rPeakrandrtroughr levelsr arerdone:
A. Whenrtherdrugrhasrarwidertherapeuticr range
B. Whenrtherdrugrwillr beradministeredr forrarshortrtimer only
C. Whenrthererisrarhighr correlationr betweenrtherdoserandrsaturationr ofrreceptorrsites
D. Tordeterminer ifr ardrugrisrinrthertherapeuticr range
r

9.rArlaboratoryrresultrindicatesrtherpeakrlevelrforrardrugrisrabovertherminimumrtoxicrcon
centration.r Thisr meansrthatrthe:
A. Concentrationr willr producertherapeuticr effects
B. Concentrationr willr produceranradverserresponse
C. Timer betweenrdosesrmustr bershortened
D. Durationr ofractionr ofrtherdrugr isrtoorlong

r rr 10.r Drugsr thatrarerreceptorragonistsr mayrdemonstrater whatr property?
A. Irreversibler bindingr tortherdrugrreceptorrsite
B. Up-regulationr withr chronicr use
C. Desensitizationr orrdown-regulationr withr continuousr use
D. Inverser relationshipr betweenrdrugrconcentrationr andrdrugraction

r rr 11.r Drugsr thatrarerreceptorrantagonists,r suchrasrbetarblockers,r mayrcause:
A. Down-regulationr ofrtherdrugr receptor
B. Anrexaggeratedr responserifr abruptlyr discontinued
C. Partialr blockaderofrthereffectsr ofragonistr drugs
D. Anrexaggeratedr responsertorcompetitiver drugragonists

r rr 12.r Factorsrthatraffectr gastricr drugr absorptionr include:
A. Liverr enzymer activity
B. Protein-bindingr propertiesr ofrtherdrugr molecule
C. Lipidr solubilityrrofrtherdrug
D. Abilityr torchewrandrswallow

r rr 13.rrDrugsr administeredr viarintravenousr (IV)rroute:
A. Needrtorberlipidr solubler inrorderrtorbereasilyr absorbed
B. Beginr distributionr intor therbodyrimmediately
C. Arereasilyr absorbedrifr theyrarernonionized
D. Mayruserpinocytosisr torberabsorbed
r

rr 14.rrWhenrarmedicationr israddedrtorarregimenr forrarsynergisticr effect,r thercombinedr effectr ofrth
erdrugsr is:
A. Thersumr ofrthereffectsr ofreachrdrugrindividually
B. Greaterrthanr thersumr ofrthereffectsr ofreachrdrugrindividually
C. Lessrthanr thereffectr ofreachrdrugrindividually
D. Notrpredictable,r asritrvariesr withr eachrindividual