,Chapter 01: Cellular Biology w w w
Huether and McCance: Understanding Pathophysiology,
w w w w
5th Edition
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Chapter 01: Cellular Biology w w w
Test Bank
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MULTIPLE CHOICE w
1. A student is observing a cell under the microscope. It is observed to have
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supercoiled DNA with histones. Which of the following would also be observed
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by the student?
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a. A single circular chromosome w w w
b. A nucleus
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c. Free-floating nuclear material w w
d. No organelles w
ANS: B w
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA
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within its nucleus; thus, the nucleus should be observed.
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A single circular chromosome is characteristic of prokaryotic cells, which do not have
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histones.
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Free-floating nuclear material describes a prokaryotic cell, which would not have a
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distinct nucleus.
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Eukaryotic cells have membrane bounded cellular components called organelles. No
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organelles describes a prokaryotic cell.
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REF: p. 2 w w
2. A nurse is instructing the staff about cellular functions. Which cellular function
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is the nurse describing when an isolated cell absorbs oxygen and uses it to
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transform nutrients to energy?
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a. Metabolic absorption w
b. Communication
c. Secretion
d. Respiration
ANS: D w
The ability of the cell to absorb oxygen refers to the cell’s function of respiration.
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,The ability of the cell to function within a society of cells refers to its function of
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communication.
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The ability of the cell to take in nutrients refers to the cell’s function of metabolic
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absorption.
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The ability of the cell to synthesize new substances and secrete these elsewhere refers
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to the cell’s function of secretion.
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REF: p. 3 w w
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell
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would most of the genetic information be contained?
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a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus
ANS: C w
The region of the cell that contains genetic material, including a large amount
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of ribonucleic acid, most of the DNA, and DNA-binding proteins, is the
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nucleolus. The mitochondria is the site of cellular respiration.
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The ribosomes are involved in manufacturing of proteins within the cell.
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The nucleus contains the nucleolus, and it is the nucleolus that contains
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genetic material.
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REF: p. 5 w w
4. The fluid mosaic model for biologic membranes describes membrane behavior.
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According to this model, which of the following float singly or as aggregates in
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the fluid lipid bilayer?
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a. Peripheral membrane proteins w w
b. Integral membrane proteins w w
c. Glycoproteins
d. Cell adhesion molecules
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ANS: B w
Integral membrane proteins float freely in the fluid lipid bilayer.
w w w w w w w w w
Peripheral membrane proteins are not embedded in the layer, but reside at the surface.
w w w w w w w w w w w w w
wGlycoproteins act as cell surface markers. w w w w w
, Cell adhesion molecules are on the outside of the membrane and allow cells to hook
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together.
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REF: p. 6w w
5. Which of the following can bind to plasma membrane receptors?
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a. Oxygen
b. Ribosomes
c. Amphipathic lipids w
d. Ligands
ANS: D w
Ligands are specific molecules that can bind with receptors on the cell membrane.
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Oxygen moves by diffusion; it does not bind to receptors.
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Ribosomes make proteins and are not involved in binding.
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Amphipathic lipids are a portion of the cell membrane.
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REF: p. 11
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6. A nurse is reviewing a report from a patient with metastatic cancer. What
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finding would support the diagnosis of metastatic cancer? Alterations in
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extracellular matrix that include:
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a. Decreased fibronectin w
b. Increased collagen w
c. Decreased elastin w
d. Increased glycoproteins w
ANS: A w
Reduced amounts of fibronectin are found in some types of cancerous cells, allowing
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cancer cells to travel, or metastasize.
w w w w w w
Collagen provides strength, and its breakdown is associated with osteoarthritis, not
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cancer.
w
Elastin is found in the lungs and allows tissues to stretch; it is not associated with
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cancerous cells.
w w
Decreased, not increased, glycoproteins are associated with cancerous cells.
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REF: p. 8
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7. Which form of cell communication is used to relate to other cells in direct
w w w w w w w w w w w w w
physical contact?
w w
Huether and McCance: Understanding Pathophysiology,
w w w w
5th Edition
w w
Chapter 01: Cellular Biology w w w
Test Bank
w w
MULTIPLE CHOICE w
1. A student is observing a cell under the microscope. It is observed to have
w w w w w w w w w w w w w
supercoiled DNA with histones. Which of the following would also be observed
w w w w w w w w w w w w
by the student?
w w w
a. A single circular chromosome w w w
b. A nucleus
w
c. Free-floating nuclear material w w
d. No organelles w
ANS: B w
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA
w w w w w w w w w w w w w w
within its nucleus; thus, the nucleus should be observed.
w w w w w w w w w
A single circular chromosome is characteristic of prokaryotic cells, which do not have
w w w w w w w w w w w w
histones.
w
Free-floating nuclear material describes a prokaryotic cell, which would not have a
w w w w w w w w w w w
distinct nucleus.
w w
Eukaryotic cells have membrane bounded cellular components called organelles. No
w w w w w w w w w
organelles describes a prokaryotic cell.
w w w w w
REF: p. 2 w w
2. A nurse is instructing the staff about cellular functions. Which cellular function
w w w w w w w w w w w
is the nurse describing when an isolated cell absorbs oxygen and uses it to
w w w w w w w w w w w w w w
transform nutrients to energy?
w w w w
a. Metabolic absorption w
b. Communication
c. Secretion
d. Respiration
ANS: D w
The ability of the cell to absorb oxygen refers to the cell’s function of respiration.
w w w w w w w w w w w w w w
,The ability of the cell to function within a society of cells refers to its function of
w w w w w w w w w w w w w w w w
communication.
w
The ability of the cell to take in nutrients refers to the cell’s function of metabolic
w w w w w w w w w w w w w w w
absorption.
w
The ability of the cell to synthesize new substances and secrete these elsewhere refers
w w w w w w w w w w w w w
to the cell’s function of secretion.
w w w w w w
REF: p. 3 w w
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell
w w w w w w w w w w w w
would most of the genetic information be contained?
w w w w w w w w
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus
ANS: C w
The region of the cell that contains genetic material, including a large amount
w w w w w w w w w w w w
of ribonucleic acid, most of the DNA, and DNA-binding proteins, is the
w w w w w w w w w w w w
nucleolus. The mitochondria is the site of cellular respiration.
w w w w w w w w w
The ribosomes are involved in manufacturing of proteins within the cell.
w w w w w w w w w w
The nucleus contains the nucleolus, and it is the nucleolus that contains
w w w w w w w w w w w
genetic material.
w w
REF: p. 5 w w
4. The fluid mosaic model for biologic membranes describes membrane behavior.
w w w w w w w w w
According to this model, which of the following float singly or as aggregates in
w w w w w w w w w w w w w w
the fluid lipid bilayer?
w w w w
a. Peripheral membrane proteins w w
b. Integral membrane proteins w w
c. Glycoproteins
d. Cell adhesion molecules
w w
ANS: B w
Integral membrane proteins float freely in the fluid lipid bilayer.
w w w w w w w w w
Peripheral membrane proteins are not embedded in the layer, but reside at the surface.
w w w w w w w w w w w w w
wGlycoproteins act as cell surface markers. w w w w w
, Cell adhesion molecules are on the outside of the membrane and allow cells to hook
w w w w w w w w w w w w w w
together.
w
REF: p. 6w w
5. Which of the following can bind to plasma membrane receptors?
w w w w w w w w w
a. Oxygen
b. Ribosomes
c. Amphipathic lipids w
d. Ligands
ANS: D w
Ligands are specific molecules that can bind with receptors on the cell membrane.
w w w w w w w w w w w w
Oxygen moves by diffusion; it does not bind to receptors.
w w w w w w w w w w
Ribosomes make proteins and are not involved in binding.
w w w w w w w w
Amphipathic lipids are a portion of the cell membrane.
w w w w w w w w w
REF: p. 11
w w
6. A nurse is reviewing a report from a patient with metastatic cancer. What
w w w w w w w w w w w w
finding would support the diagnosis of metastatic cancer? Alterations in
w w w w w w w w w w
extracellular matrix that include:
w w w w
a. Decreased fibronectin w
b. Increased collagen w
c. Decreased elastin w
d. Increased glycoproteins w
ANS: A w
Reduced amounts of fibronectin are found in some types of cancerous cells, allowing
w w w w w w w w w w w w
cancer cells to travel, or metastasize.
w w w w w w
Collagen provides strength, and its breakdown is associated with osteoarthritis, not
w w w w w w w w w w
cancer.
w
Elastin is found in the lungs and allows tissues to stretch; it is not associated with
w w w w w w w w w w w w w w w
cancerous cells.
w w
Decreased, not increased, glycoproteins are associated with cancerous cells.
w w w w w w w w
REF: p. 8
w w w
7. Which form of cell communication is used to relate to other cells in direct
w w w w w w w w w w w w w
physical contact?
w w
