NBME Biochemistry Shelf Exam 2025 Questions
and Answers
, What neurotransmitter stimulates release of epinephrine from adrenal medulla? - Answer-
acetylcholine
What is a metabolite if epinephrine that suggests epi-secreting carcinoma? What is another assoc
symptom? - Answer- metanephrine; assoc with HBP
What does acetazolamide (carbonic anhydrase ib) treat? - Answer- glaucoma, epilepsy, altitude sickness,
congestive heart failure
can cause dehydration
Sickle cell anemia is due to... - Answer- pt mutation of Glu -> val
What is a major neurotransmitter amino acid? - Answer- Glu
HA protein of influenza binds to - Answer- cytokine receptors
What is a reducing-sugar test? - Answer- Tests for aldo-keto sugars
What is omeprazole? - Answer- proton pump ib
Name some GAG's. - Answer- heparin sulfate, chondroitin sulfate,
What type of reaction is glucuronidation? - Answer- oxidation
In Marfan's syndrome, what part of fibrillin's protein structure is affected? - Answer- primary structure
What are the symptoms of Huntington's disease? - Answer- anxiety, uncontrollable mvmts, slurring of
speech, difficulty focusing or concentrating; caused by triple repeat expansion
What is Chediak-Higashi syndrome? - Answer- phagocyte deficiency ->
hypergammaglobulinemia, significant neutropenia,
In exposure to carbon monoxide or cyanide, which way does the ox sat curve shift? - Answer- to the
L; increased affinity at low pO_2
What is pralidoxime chloride? - Answer- reactivate acetylcholinesterase
and Answers
, What neurotransmitter stimulates release of epinephrine from adrenal medulla? - Answer-
acetylcholine
What is a metabolite if epinephrine that suggests epi-secreting carcinoma? What is another assoc
symptom? - Answer- metanephrine; assoc with HBP
What does acetazolamide (carbonic anhydrase ib) treat? - Answer- glaucoma, epilepsy, altitude sickness,
congestive heart failure
can cause dehydration
Sickle cell anemia is due to... - Answer- pt mutation of Glu -> val
What is a major neurotransmitter amino acid? - Answer- Glu
HA protein of influenza binds to - Answer- cytokine receptors
What is a reducing-sugar test? - Answer- Tests for aldo-keto sugars
What is omeprazole? - Answer- proton pump ib
Name some GAG's. - Answer- heparin sulfate, chondroitin sulfate,
What type of reaction is glucuronidation? - Answer- oxidation
In Marfan's syndrome, what part of fibrillin's protein structure is affected? - Answer- primary structure
What are the symptoms of Huntington's disease? - Answer- anxiety, uncontrollable mvmts, slurring of
speech, difficulty focusing or concentrating; caused by triple repeat expansion
What is Chediak-Higashi syndrome? - Answer- phagocyte deficiency ->
hypergammaglobulinemia, significant neutropenia,
In exposure to carbon monoxide or cyanide, which way does the ox sat curve shift? - Answer- to the
L; increased affinity at low pO_2
What is pralidoxime chloride? - Answer- reactivate acetylcholinesterase
