15th Edition by Bertram G. Katzung, Verified
Chapters 1 – 66
,Table of Contents
1. Introduction: The Nature of Drugs & Drug Development & Regulation
2. Drug Receptors & Pharmacodynamics
3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action
4. Drug Biotransformation
5. Pharmacogenomics
6. Introduction to Autonomic Pharmacology
7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs
8. Cholinoceptor-Blocking Drugs
9. Adrenoceptor Agonists & Sympathomimetic Drugs
10. Adrenoceptor Antagonist Drugs
11. Antihypertensive Agents
12. Vasodilators & the Treatment of Angina Pectoris
13. Drugs Used in Heart Failure
14. Agents Used in Cardiac Arrhythmias
15. Diuretic Agents
16. Histamine, Serotonin, & the Ergot Alkaloids
17. Vasoactive Peptides
18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
19. Nitric Oxide
20. Drugs Used in Asthma
21. Introduction to the Pharmacology of CNS Drugs
22. Sedative-Hypnotic Drugs
23. The Alcohols
24. Antiseizure Drugs
25. General Anesthetics
26. Local Anesthetics
27. Skeletal Muscle Relaxants
28. Pharmacologic Management of Parkinsonism & Other Movement Disorders
29. Antipsychotic Agents & Lithium
30. Antidepressant Agents
31. Opioid Agonists & Antagonists
32. Drugs of Abuse
33. Agents Used in Cytopenias; Hematopoietic Growth Factors
34. Drugs Used in Disorders of Coagulation
35. Agents Used in Dyslipidemia
36. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid
Analgesics, &
Drugs Used in Gout
37. Hypothalamic & Pituitary Hormones
38. Thyroid & Antithyroid Drugs
39. Adrenocorticosteroids & Adrenocortical Antagonists
40. The Gonadal Hormones & Inhibitors
41. Pancreatic Hormones & Antidiabetic Drugs
42. Agents That Affect Bone Mineral Homeostasis
43. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics
,44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidinones
45. Aminoglycosides & Spectinomycin
46. Sulfonamides, Trimethoprim, & Quinolones
47. Antimycobacterial Drugs
48. Antifungal Agents
49. Antiviral Agents
50. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants
51. Clinical Use of Antimicrobial Agents
52. Antiprotozoal Drugs
53. Clinical Pharmacology of the Antihelminthic Drugs
54. Cancer Chemotherapy
55. Immunopharmacology
56. Introduction to Toxicology: Occupational & Environmental
57. Heavy Metal Intoxication & Chelators
58. Management of the Poisoned Patient
59. Special Aspects of Perinatal & Pediatric Pharmacology
60. Special Aspects of Geriatric Pharmacology
61. Dermatologic Pharmacology
62. Drugs Used in the Treatment of Gastrointestinal Diseases
63. Therapeutic & Toxic Potential of Over-the-Counter Agents
64. Dietary Supplements & Herbal Medications
65. Rational Prescribing & Prescription Writing
66. Important Drug Interactions & Their Mechanisms
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
1. A nurse working in radiology administers iodine to a patient who is
having a computed tomography (CT) scan. The nurse working on the
oncology unit administers chemotherapy to patients who have cancer. At
the Public Health Department, a nurse administers a measles-mumps-
rubella (MMR) vaccine toa 14-month-old child as a routine
immunization. Which branch of pharmacology best describes the actions
of all three nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
, Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses
are involved with clinical pharmacology or pharmacotherapeutics,
which is a branch of pharmacology that deals with the uses of drugs to
treat, prevent, and diagnose disease. The radiology nurse is
administering a drug to help diagnose a disease. The oncology nurse is
administering a drug to help treat adisease. Pharmacoeconomics
includes any costs involved in drug therapy.
Pharmacodynamics involves how a drug affects the body
andpharmacokinetics is how the body acts on the body.
2. When involved in phase III drug evaluation studies,
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what responsibilitieswould the nurse have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate patients to be involved in the drug study
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C) Monitoring and observing patients closely for adverse effects
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D) Conducting research to determine effectiveness of the drug
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Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in
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Vwhichpatients are asked to record any symptoms they experience
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Vwhile taking thedrugs. Nurses may be responsible for helping collect
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Vand analyze the information to be shared with the Food and Drug
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VAdministration (FDA) butwould not conduct research independently
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Vbecause nurses do not prescribe medications. Use of animals in drug
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Vtesting is done in the preclinical trials. Select patients who are
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involved in phase II studies to participate in studies where the
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participants have the disease the drug is intended to treat. These
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patients are monitored closely for drug action and adverse effects.
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Phase I studies involve healthy human volunteers who are usually
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paid for their participation. Nurses may observe for adverse effects
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and toxicity.
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