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Naloxone
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1 Purpose of inflammation 2 Leukocytosis vs Leukopenia
Vascular Stage of inflammation
3 Antidote for opioid overdose 4
(Capillary Permeability)
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Terms in this set (135)
A limit effects of injury, Remove damaged tissue,
Purpose of inflammation
Generate tissue, Promote healing
Manifestation of Greater the injury greater the response, what foreign
inflammation agent caused injury
, Systemic effects of Fever promotes inflammatory response throughout
inflammation whole body
1) after blood flow is increased, a brief
Vascular stage of vasoconstriction occurs following immediate injury
inflammation (Blood 2) vasodilation of arterioles occurs in capillary beds.
flow) 3) the permeability of microcirculation increases 4)
the following vasodilation causes redness & heat
Vascular Stage of 1) increased capillary permeability results in leaking
inflammation (Capillary fluid, causing swelling, pain & loss of function. 2) This
Permeability) works to dilute toxins & enhance clot formation
1) Margination occurs, accumulating WBC &
adhesion to the endothelium 2) WBC are then
transmigrated across the endothelium 3)
Cellular stage of Chemotaxis pulls cells towards injured site 4) WBC
inflammation reach site of injury, Activating & eating foreign
objects. opsonizing coat some particles in a
negative particle to increase chance of being
increased
1) Acute protective, self limited - short duration of <2
Types of inflammatory
weeks, rapid onset 2) chronic - not
Reaction
protective/beneficial, could cause
1) Resolution-tissue is healed & returned to normal
Results of acute
2) Necrosis / scarring -tissue is permanently
inflammation
damaged
Cardinal signs of Redness, Heat, swelling, loss of function
inflammation (Acute)
Self perpetuating & can last for weeks to years,
Develops from acute, can increase susceptibility to
Chronic inflammation
cancer, causes autoimmune disease where body
fights itself
Blood tests for A. Erythrocyte Sedimentation rate, C-reactive
inflammation protein (most useful), Fibrinogen
Normal range of WBC 5,000-10,000
per mL