ANAT 6512 E3 LYMPHATIC SYSTEM HISTOLOGY
QUESTIONS WITH CORRECT ANSWERS 2025
What are the major functions of the lymphatic system? - CORRECT ANSWER --
drain excess interstitial fluid: return excess interstitial fluid to blood stream to help maintain normal blo
od volume and prevent edema
-provide an alternative transportation route for hormones, nutrients, and waste products
-immune response: produce, maintain and distribute lymphocytes
What are the main components of the lymphatic system? - CORRECT ANSWER --lymphatic vessels
-lymphocytes and variety of supporting cells
-diffuse lymphatic tissue
-lymphatic nodules
-lymph nodes
-spleen
-bone marrow
-thymus
How do lymphatic vessels begin? - CORRECT ANSWER --as networks of blind-
ended capillaries in microcapillary beds
-
lymphatic capillaries form network within loose connective tissues (especially numerous beneath epithe
lium of skin and mucous membranes
What are the characteristics of lymphatic capillaries? - CORRECT ANSWER --
endothelial tubes lacking continuous basal lamina, results in high permeability
-allows for entry of large molecules, antigens, cells
-
collect excess protein rich extracellular fluid from extracellular spaces (fluid referred to as lymph once it
enters lymphatic vessel
How does lymph move throughout the body? - CORRECT ANSWER --
bundles of smooth muscles as vessels become larger
, -
there is no central pump in lymphatic system, it moves sluggishly; relies primarily on skeletal muscle co
mpression of vessels
-lymphatic vessels possess valves--> prevent backflow of lymph, aid in unidirectional flow
What are the two main channels of lymphatic vessels? - CORRECT ANSWER --
thoracic duct: largest lymphatic vessel; drains majority of body
-right lymphatic duct: drains right upper limb, right thorax, right neck and right head
What are lymphocytes? - CORRECT ANSWER --definitive cells of lymphatic system; effector cells
-3 major types of lymphocytes: B, T and NK cells
What are supporting cells? - CORRECT ANSWER --
interact with lymphocytes; antigen presentation and regulation of immune responses
What are the characteristics of B lymphocytes? - CORRECT ANSWER --
first recognized in Bursa of Fabricius of birds
-represent 20-30% of circulating lymphocytes
-membrane-bound B-cell receptor immunoglobulin
-activated B cells (Plasma cells) secrete non-membrane bound form of immunoglobulins= Antibodies
-Humoral immunity= secretion of antibodies into the blood upon B cell activation
What are the characteristics of T lymphocytes? - CORRECT ANSWER --mature in the thymus
-represent 60-80% of circulating lymphocytes
-cell-mediated immunity- involves cell-
cell interactions and release of cytokines; directed against intracellular pathogens
-subclassified based on presence/absence of cell surface markers: CD4+ and CD8+
What are the characteristics of NK cells? - CORRECT ANSWER --represent 5-
10% of circulating lymphocytes
-potent killers of certain types of target cells, namely virally infected and malignant cells
QUESTIONS WITH CORRECT ANSWERS 2025
What are the major functions of the lymphatic system? - CORRECT ANSWER --
drain excess interstitial fluid: return excess interstitial fluid to blood stream to help maintain normal blo
od volume and prevent edema
-provide an alternative transportation route for hormones, nutrients, and waste products
-immune response: produce, maintain and distribute lymphocytes
What are the main components of the lymphatic system? - CORRECT ANSWER --lymphatic vessels
-lymphocytes and variety of supporting cells
-diffuse lymphatic tissue
-lymphatic nodules
-lymph nodes
-spleen
-bone marrow
-thymus
How do lymphatic vessels begin? - CORRECT ANSWER --as networks of blind-
ended capillaries in microcapillary beds
-
lymphatic capillaries form network within loose connective tissues (especially numerous beneath epithe
lium of skin and mucous membranes
What are the characteristics of lymphatic capillaries? - CORRECT ANSWER --
endothelial tubes lacking continuous basal lamina, results in high permeability
-allows for entry of large molecules, antigens, cells
-
collect excess protein rich extracellular fluid from extracellular spaces (fluid referred to as lymph once it
enters lymphatic vessel
How does lymph move throughout the body? - CORRECT ANSWER --
bundles of smooth muscles as vessels become larger
, -
there is no central pump in lymphatic system, it moves sluggishly; relies primarily on skeletal muscle co
mpression of vessels
-lymphatic vessels possess valves--> prevent backflow of lymph, aid in unidirectional flow
What are the two main channels of lymphatic vessels? - CORRECT ANSWER --
thoracic duct: largest lymphatic vessel; drains majority of body
-right lymphatic duct: drains right upper limb, right thorax, right neck and right head
What are lymphocytes? - CORRECT ANSWER --definitive cells of lymphatic system; effector cells
-3 major types of lymphocytes: B, T and NK cells
What are supporting cells? - CORRECT ANSWER --
interact with lymphocytes; antigen presentation and regulation of immune responses
What are the characteristics of B lymphocytes? - CORRECT ANSWER --
first recognized in Bursa of Fabricius of birds
-represent 20-30% of circulating lymphocytes
-membrane-bound B-cell receptor immunoglobulin
-activated B cells (Plasma cells) secrete non-membrane bound form of immunoglobulins= Antibodies
-Humoral immunity= secretion of antibodies into the blood upon B cell activation
What are the characteristics of T lymphocytes? - CORRECT ANSWER --mature in the thymus
-represent 60-80% of circulating lymphocytes
-cell-mediated immunity- involves cell-
cell interactions and release of cytokines; directed against intracellular pathogens
-subclassified based on presence/absence of cell surface markers: CD4+ and CD8+
What are the characteristics of NK cells? - CORRECT ANSWER --represent 5-
10% of circulating lymphocytes
-potent killers of certain types of target cells, namely virally infected and malignant cells
