MH701 SAFETY EXAM 1 REVIEW QUESTIONS
Which neurotransmitters are most theorized when decreased lead to depression and
anxiety? - Answer -Norepinephrine and Serotonin
The difference in the daignosis of dysthymia vs. MDD is dysthymia must present for
how long? - Answer -2 years-Someone with dysthymia has that "everything is just ok",
nothings great everyday mood. Struggle with when last happy. MDD patient has a 2
week period of depression with symptoms of trouble sleeping, appetite, insight, guilt,
concetration, pleasure, suicidal thoughts. MDD they remember being happy, not always
sad and angry.
A non-addictive and non habit forming alternative for the use in treating anxiety? -
Answer -Buspirone or Buspar-Take everyday, 2 times/day to see the most effect 4-6
weeks. Good add-on to antidepressant and also good for children.
Substance to avoid when taking MAOIs and why? - Answer -Tyramine and
hypertensive crisis-Hardly seen in practice and used for last resort. Causes very high
pressure. Tyramine items such as hotdogs, processed meat, sausage, pepperoni,
chocolate, avocodoes, guac, raisins, bananas, yeasts, swiss cheese, blue cheese,
wine, beer, alcohol, aged cheese.
What SSRI has a shorter half-life and most often need to be weened to prevent issues
with discontinuation? - Answer -Paroxetine of Paxil-Pt. needs to be monitored due to
days they will feel great or a low drop in their mood because of the half-life. Have a hard
time discontinuing, have more anxiety, dizzy feeling. Paxil causes weight gain and
sexual S/E.
What class of antidepressants is more lethal in an overdose? - Answer -TCAs-MOre
lethal, SSRIs are safer. TCAs conducton of heart issues such as EKG changes and
more drying.
What is a patient likely to exhibit if they suddenly stop taking Venlafaxine (Effexor)? -
Answer -Discontinuation Syndrome-A rebound effect, feel worse than before starting the
drug. Dizziness, blurry, nausea, cloudy feeling. Can feel a difference in 2-3 days.
Educate patient on this if they are non-compliant. Must slowly ween off medication, so
they do not have the effects.
SSRI that can often interact with many OTC and prescription drugs? - Answer -
Fluvoxamine-Interacts with OTC cold medications ie. sudafed, decongestat. Educate
patients on the possible risks involved.
What antidepressant is contraindicated with seizure disorders, anorexia, and bulemia? -
Answer -Buproprion (Wellbutrin)-Do not want to overstimulate the brain, causing a
seizure; with eating disorders electrolytes are out of balance and predisposed to having
a seizure. This med actually helps to DECREASE appetite.
Which neurotransmitters are most theorized when decreased lead to depression and
anxiety? - Answer -Norepinephrine and Serotonin
The difference in the daignosis of dysthymia vs. MDD is dysthymia must present for
how long? - Answer -2 years-Someone with dysthymia has that "everything is just ok",
nothings great everyday mood. Struggle with when last happy. MDD patient has a 2
week period of depression with symptoms of trouble sleeping, appetite, insight, guilt,
concetration, pleasure, suicidal thoughts. MDD they remember being happy, not always
sad and angry.
A non-addictive and non habit forming alternative for the use in treating anxiety? -
Answer -Buspirone or Buspar-Take everyday, 2 times/day to see the most effect 4-6
weeks. Good add-on to antidepressant and also good for children.
Substance to avoid when taking MAOIs and why? - Answer -Tyramine and
hypertensive crisis-Hardly seen in practice and used for last resort. Causes very high
pressure. Tyramine items such as hotdogs, processed meat, sausage, pepperoni,
chocolate, avocodoes, guac, raisins, bananas, yeasts, swiss cheese, blue cheese,
wine, beer, alcohol, aged cheese.
What SSRI has a shorter half-life and most often need to be weened to prevent issues
with discontinuation? - Answer -Paroxetine of Paxil-Pt. needs to be monitored due to
days they will feel great or a low drop in their mood because of the half-life. Have a hard
time discontinuing, have more anxiety, dizzy feeling. Paxil causes weight gain and
sexual S/E.
What class of antidepressants is more lethal in an overdose? - Answer -TCAs-MOre
lethal, SSRIs are safer. TCAs conducton of heart issues such as EKG changes and
more drying.
What is a patient likely to exhibit if they suddenly stop taking Venlafaxine (Effexor)? -
Answer -Discontinuation Syndrome-A rebound effect, feel worse than before starting the
drug. Dizziness, blurry, nausea, cloudy feeling. Can feel a difference in 2-3 days.
Educate patient on this if they are non-compliant. Must slowly ween off medication, so
they do not have the effects.
SSRI that can often interact with many OTC and prescription drugs? - Answer -
Fluvoxamine-Interacts with OTC cold medications ie. sudafed, decongestat. Educate
patients on the possible risks involved.
What antidepressant is contraindicated with seizure disorders, anorexia, and bulemia? -
Answer -Buproprion (Wellbutrin)-Do not want to overstimulate the brain, causing a
seizure; with eating disorders electrolytes are out of balance and predisposed to having
a seizure. This med actually helps to DECREASE appetite.
