ANSWERS 2025
K dependent coagulation factors CORRECT ANSWER -II, VII, IX, X
What inhibits vitamin K dependent coagulation factors? CORRECT ANSWER -Warfarin (oral)
Factor VIII deficiency is also called CORRECT ANSWER -Hemophilia A
Factor IX deficiency is also called CORRECT ANSWER -Hemophilia B
What evaluates adequacy of fibrinogen in heparinized pts? CORRECT ANSWER -RPR
von Willebrand factor CORRECT ANSWER -
Mediate a bridge between glycoprotein complex on platelets and collagen on sub endothelial su
rface (defect can cause impaired platelet adhesion and aggregation)
Stuart-Prower factor CORRECT ANSWER -X-
factor, is a part of cleaning prothrombin into thrombin
Hageman factor CORRECT ANSWER -
Factor XII, is in the intrinsic pathway, activates Fletcher factor
Fletcher Factor CORRECT ANSWER -Pre-K in intrinsic pathway and activates factor XI
Streptokinase CORRECT ANSWER -Exogenous activator for plasminogen in fibrinolytic system
What is the end product of coagulation cascade? CORRECT ANSWER -fibrin
,Intrinsic and common passway CORRECT ANSWER -aPTT
extrinsic and common pathways CORRECT ANSWER -PT
Average bleeding time CORRECT ANSWER -1-7min
Common pathway factors CORRECT ANSWER -X, V, II, I
extrinsic factors CORRECT ANSWER -VII
intrinsic factors CORRECT ANSWER -XII, XI, IX, VIII
Fibrinolysis CORRECT ANSWER -dissolution of a clot
Primary homeostasis CORRECT ANSWER -Formation of non-stable platelet plug
Secondary homeostasis CORRECT ANSWER -Formation of durable fibrin strand
Most specific fibrinogen function test, not affected by heparin CORRECT ANSWER -
thrombin time
Non-specific fibrinogen function test CORRECT ANSWER -PT and PTT
VLDLBCORRECT ANSWER -endogenous triglycerides transport
, Chylomicrons CORRECT ANSWER -exogenous triglycerides transport
0 0 0 0 0
HDL and LDLBCORRECT ANSWER -Cholesterol transport
0 0 0 0 0
adult hemoglobin CORRECT ANSWER -2 alpha and 2 beta chains
0 0 0 0 0 0 0 0 0
fetal hemoglobin CORRECT ANSWER -2 alpha and 2 gamma
0 0 0 0 0 0 0 0
Hemoglobin A2 CORRECT ANSWER -2 alpha and 2 delta
0 0 0 0 0 0 0 0
Type I hypersensitivity CORRECT ANSWER -IgE mediated
0 0 0 0 0 0
Type II hypersensitivity CORRECT ANSWER -IgG
0 0 0 0 0
Type III hypersensitivity CORRECT ANSWER -IgM and IgG
0 0 0 0 0 0 0
Heinz bodies lead to CORRECT ANSWER -G6PD deficiency
0 0 0 0 0 0 0
Microangiopathic Hemolytic Anemia CORRECT ANSWER - Schistocytes0 0 0 0 0 0
ceratocytes and teardrop cells
0 0 0 0
Abetalipoproteinemia CORRECT ANSWER -Acanthocytes 0 0 0
Beta Thalassemia CORRECT ANSWER -target cells (codocytes)
0 0 0 0 0 0
Howell-Jolly bodies CORRECT ANSWER -DNA
0 0 0 0
, Heinz bodies CORRECT ANSWER -denatured hemoglobin
0 0 0 0 0
Papperheimer bodies CORRECT ANSWER -Nonferritin iron
0 0 0 0 0
Dohle bodies CORRECT ANSWER -Rrna in leukocytes
0 0 0 0 0 0
Alpha thalassemia minor CORRECT ANSWER -two genes are defective
0 0 0 0 0 0 0 0
Alpha, thalassemia major CORRECT ANSWER -four genes are defective
0 0 0 0 0 0 0 0
silent carrier of alpha thalassemia CORRECT ANSWER -One gene is defective
0 0 0 0 0 0 0 0 0 0
Hemoglobin H disease CORRECT ANSWER -3 a-genes deleted
0 0 0 0 0 0 0
-more likely asian
0 0
Immunoglobulin light chain consist of CORRECT ANSWER -Kappa and lambda
0 0 0 0 0 0 0 0 0
Serum protein can be separated by cellulose acetate electrophoresis into 5 fractions -
0 0 0 0 0 0 0 0 0 0 0 0
CORRECT ANSWER -Albumin, alpha1 globulin, alpha2 globulin, beta globulin and delta globulin
0 0 0 0 0 0 0 0 0 0 0
Acutr hemolytic transfusion rxn CORRECT ANSWER - Hemoglobinemia,
0 0 0 0 0 0 0
hemoglobinuria, hypertension
0 0
Hemoglobinuria CORRECT ANSWER -excess hemoglobin in urine0 0 0 0 0 0
adult bone marrow red cells most abundant CORRECT ANSWER -Metamyelo (3-20%)
0 0 0 0 0 0 0 0 0 0