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Acid-Base Imbalance – 52 Exam Questions with Answers | NUR 623 | Nursing | Respiratory & Metabolic Acidosis, Alkalosis, ABG Interpretation

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This document features 52 expertly crafted exam questions with detailed answers for NUR 623 – Acid-Base Imbalance, specifically designed for the 2025/2026 academic year. It comprehensively covers essential topics such as respiratory and metabolic acidosis and alkalosis, acid-base compensation, ABG interpretation, and nursing interventions for various clinical scenarios. Each answer is structured to reinforce critical thinking and application of theoretical knowledge to real-world nursing practice. Students will find in-depth explanations on buffer systems, renal and respiratory regulation of pH, lab value interpretation, and the recognition of mixed acid-base disorders. The content aligns with current nursing education standards and clinical expectations, making it a powerful resource for both coursework and licensure exam preparation. This material is suitable for: Bachelor of Science in Nursing (BSN) students Master of Science in Nursing (MSN) candidates Nurse Practitioner (NP) programs Students in advanced pathophysiology, pharmacology, or health assessment courses Allied health students needing acid-base review Perfect for exam prep, classroom revision, and clinical application, this document is a must-have for serious nursing learners. Keywords: acid-base imbalance, respiratory acidosis, respiratory alkalosis, metabolic acidosis, metabolic alkalosis, ABG interpretation, compensated acidosis, buffer systems, nursing exam questions, nursing interventions, NUR 623, renal compensation, respiratory compensation, advanced pathophysiology, clinical nursing

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NUR 623 Acid-Base Imbalance 2025/2026
Exam Questions and Detailed Answers |
Get it 100% Correct Answers



True or False: Acid is normal - metabolic by-product

True or False: Acid is transported by the blood


True or False: Acid is eliminated by lungs & kidneys - 🧠 ANSWER ✔✔True,

True, True

Respiratory compensation involves the excretion or retention of which gas

or substance? - 🧠 ANSWER ✔✔CO2


True or False. The respiratory system is the fastest mechanism for acid-

base homeostasis. - 🧠 ANSWER ✔✔False, it is the buffer system (blood)


-Respiratory system can take minutes or it can take hours

-Slowest: Kidneys

,Which of the following alterations is evidence that the kidneys are

compensating for a respiratory acidosis condition? - 🧠 ANSWER

✔✔Elevated HCO3-


What do we think when we are talking about kidneys? lungs? - 🧠 ANSWER

✔✔Kidneys = bicarbonate


Lungs = CO2


Normal pH range - 🧠 ANSWER ✔✔7.35-7.45




Outside this range, proteins are denatured, enzymes lose their function for

many life-sustaining processes :

-Maintenance of energy stores

-Intracellular transportation and signaling systems

What is it called when pH is less than 7.35? More than 7.45? - 🧠 ANSWER

✔✔-When pH is under 7.35 = Acidosis (in blood = acidemia)


-When pH is over 7.45 = Alkalosis (in blood = alkalemia)

What is the normal Ratio of Carbonic Acid (H2CO3) to Base Bicarbonate

(HCO3-) - 🧠 ANSWER ✔✔1:20

, What are the 3 mechanisms for maintaining pH between 7.35 & 7.45? - 🧠

ANSWER ✔✔BUFFER SYSTEM (seconds): within the body cells


-ECF Buffers, Phosphate system, Proteins, Hemoglobin, Cells

-Substance that releases or binds H+ to create a stable pH

-Buffers change strong acids to weak acids or bind to acids to neutralise

their effect.

-Buffers minimize effect of acids on pH until can be excreted from body.




RESP SYSTEM (minutes): within the lungs

CO2 + H20 ↔ H2CO3 ↔ H+ + HCO3-

(Lungs) (RBCs) (Buffered)

-Dec. respirations = more CO2 = more carbonic acid = more H+ = more

acidic

-Inc. respirations = less CO2 = less carbonic acid = less H+ = more alkaline




RENAL SYSTEM (hours/days): within the kidneys




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Subido en
21 de septiembre de 2025
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