MCCANCE & HUETHER’S PATHOPHYSIOLOGY - BINDER READY: THE BIOLOGIC
BASIS FOR DISEASE IN ADULTS AND CHILDREN 9TH EDITION BY JULIA ROGERS
DNP APRN CNS FNP-BC FAANP (2025) ||LATEST EDITION
9th edition
,table of contents
part one: basic concepts of pathophysiology........................................................................ 5
unit 1: the cell ....................................................................................................................... 5
chapter 1. cellular biology........................................................................................................... 5
chapter 2. genes and genetic diseases ..................................................................................... 36
chapter 3. epigenetics and disease ........................................................................................... 65
chapter 4. altered cellular and tissue biology ........................................................................... 71
chapter 5. fluids and electrolytes, acids and bases ................................................................ 102
unit 2: mechanisms of self-defense ..................................................................................... 136
chapter 6. innate immunity: inflammation and wound healing ............................................. 136
chapter 7. adaptive immunity ................................................................................................. 164
chapter 8. alterations in immunity ......................................................................................... 192
chapter 9. infection and defects in mechanisms of defense .................................................. 198
chapter 10. stress and disease ................................................................................................ 231
unit 3: cellular proliferation: cancer ................................................................................... 247
chapter 11. biology of cancer ................................................................................................. 247
chapter 12. cancer epidemiology ........................................................................................... 264
chapter 13. cancer in children and adolescents ..................................................................... 279
part two: body systems and diseases ................................................................................. 288
unit 4: the neurologic system ............................................................................................. 289
chapter 14. structure and function of the neurologic system ................................................ 289
chapter 15. pain, temperature, sleep, and sensory function ................................................. 326
chapter 16. alterations in cognitive systems, cerebral hemodynamics, and motor function 364
chapter 17. disorders of the central and peripheral nervous systems and neuromuscular
junction ................................................................................................................................... 401
chapter 18. alterations of neurologic function in children ..................................................... 441
unit 5: the endocrine system .............................................................................................. 469
chapter 19. mechanisms of hormonal regulation .................................................................. 469
chapter 20. alterations of hormonal regulation ..................................................................... 494
chapter 21. obesity and disorders of nutrition ....................................................................... 535
,unit 6: the hematologic system .......................................................................................... 541
chapter 22. structure and function of the hematologic system ............................................. 541
chapter 23. alterations of hematologic function .................................................................... 567
chapter 24. alterations of hematologic function in children .................................................. 616
unit 7: the cardiovascular and lymphatic systems ............................................................... 647
chapter 25. structure and function of the cardiovascular and lymphatic systems ................. 647
chapter 26. alterations of cardiovascular function ................................................................. 679
chapter 27. alterations of cardiovascular function in children ............................................... 711
unit 8: the pulmonary system ............................................................................................ 735
chapter 28. structure and function of the pulmonary system ................................................ 735
chapter 29. alterations of pulmonary function....................................................................... 766
chapter 30. alterations of pulmonary function in children..................................................... 807
unit 9: the renal and urologic systems ................................................................................ 833
chapter 31. structure and function of the renal and urologic systems .................................. 833
chapter 32. alterations of renal and urinary tract function .................................................... 861
chapter 33. alterations of renal and urinary tract function in children .................................. 893
unit 10: the reproductive systems ...................................................................................... 913
chapter 34. structure and function of the reproductive systems ........................................... 913
chapter 35. alterations of the female reproductive system ................................................... 946
chapter 36. alterations of the male reproductive system....................................................... 969
unit 11: the digestive system ............................................................................................. 986
chapter 37. structure and function of the digestive system ................................................... 986
chapter 38. alterations of digestive function ........................................................................ 1014
chapter 39. alterations of digestive function in children ...................................................... 1051
unit 12: the musculoskeletal and integumentary systems ..................................................1083
chapter 40. structure and function of the musculoskeletal system ..................................... 1083
chapter 41. alterations of musculoskeletal function ............................................................ 1113
chapter 42. alterations of musculoskeletal function in children .......................................... 1148
chapter 43. structure, function, and disorders of the integument ....................................... 1169
, chapter 44. alterations of the integument in children.......................................................... 1194
BASIS FOR DISEASE IN ADULTS AND CHILDREN 9TH EDITION BY JULIA ROGERS
DNP APRN CNS FNP-BC FAANP (2025) ||LATEST EDITION
9th edition
,table of contents
part one: basic concepts of pathophysiology........................................................................ 5
unit 1: the cell ....................................................................................................................... 5
chapter 1. cellular biology........................................................................................................... 5
chapter 2. genes and genetic diseases ..................................................................................... 36
chapter 3. epigenetics and disease ........................................................................................... 65
chapter 4. altered cellular and tissue biology ........................................................................... 71
chapter 5. fluids and electrolytes, acids and bases ................................................................ 102
unit 2: mechanisms of self-defense ..................................................................................... 136
chapter 6. innate immunity: inflammation and wound healing ............................................. 136
chapter 7. adaptive immunity ................................................................................................. 164
chapter 8. alterations in immunity ......................................................................................... 192
chapter 9. infection and defects in mechanisms of defense .................................................. 198
chapter 10. stress and disease ................................................................................................ 231
unit 3: cellular proliferation: cancer ................................................................................... 247
chapter 11. biology of cancer ................................................................................................. 247
chapter 12. cancer epidemiology ........................................................................................... 264
chapter 13. cancer in children and adolescents ..................................................................... 279
part two: body systems and diseases ................................................................................. 288
unit 4: the neurologic system ............................................................................................. 289
chapter 14. structure and function of the neurologic system ................................................ 289
chapter 15. pain, temperature, sleep, and sensory function ................................................. 326
chapter 16. alterations in cognitive systems, cerebral hemodynamics, and motor function 364
chapter 17. disorders of the central and peripheral nervous systems and neuromuscular
junction ................................................................................................................................... 401
chapter 18. alterations of neurologic function in children ..................................................... 441
unit 5: the endocrine system .............................................................................................. 469
chapter 19. mechanisms of hormonal regulation .................................................................. 469
chapter 20. alterations of hormonal regulation ..................................................................... 494
chapter 21. obesity and disorders of nutrition ....................................................................... 535
,unit 6: the hematologic system .......................................................................................... 541
chapter 22. structure and function of the hematologic system ............................................. 541
chapter 23. alterations of hematologic function .................................................................... 567
chapter 24. alterations of hematologic function in children .................................................. 616
unit 7: the cardiovascular and lymphatic systems ............................................................... 647
chapter 25. structure and function of the cardiovascular and lymphatic systems ................. 647
chapter 26. alterations of cardiovascular function ................................................................. 679
chapter 27. alterations of cardiovascular function in children ............................................... 711
unit 8: the pulmonary system ............................................................................................ 735
chapter 28. structure and function of the pulmonary system ................................................ 735
chapter 29. alterations of pulmonary function....................................................................... 766
chapter 30. alterations of pulmonary function in children..................................................... 807
unit 9: the renal and urologic systems ................................................................................ 833
chapter 31. structure and function of the renal and urologic systems .................................. 833
chapter 32. alterations of renal and urinary tract function .................................................... 861
chapter 33. alterations of renal and urinary tract function in children .................................. 893
unit 10: the reproductive systems ...................................................................................... 913
chapter 34. structure and function of the reproductive systems ........................................... 913
chapter 35. alterations of the female reproductive system ................................................... 946
chapter 36. alterations of the male reproductive system....................................................... 969
unit 11: the digestive system ............................................................................................. 986
chapter 37. structure and function of the digestive system ................................................... 986
chapter 38. alterations of digestive function ........................................................................ 1014
chapter 39. alterations of digestive function in children ...................................................... 1051
unit 12: the musculoskeletal and integumentary systems ..................................................1083
chapter 40. structure and function of the musculoskeletal system ..................................... 1083
chapter 41. alterations of musculoskeletal function ............................................................ 1113
chapter 42. alterations of musculoskeletal function in children .......................................... 1148
chapter 43. structure, function, and disorders of the integument ....................................... 1169
, chapter 44. alterations of the integument in children.......................................................... 1194
