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HESI NCLEX-RN Test Bank 2025 – High-Yield Mixed Topics with Answers & Rationales

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Subido en
19-09-2025
Escrito en
2025/2026

Boost your HESI NCLEX-RN prep with this comprehensive 200-question test bank covering maternal-newborn, pharmacology, med-surg, mental health, pediatrics, and critical care. Each question comes with answers and rationales, designed to help nursing students master high-yield topics, reinforce clinical reasoning, and improve exam confidence. Perfect for HESI review, NCLEX prep, or classroom practice, this test bank is mixed-topic and updated for 2025, reflecting common concepts and scenarios students encounter.

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HESI NCLEX-RN Test Bank – Mixed Topics


1. A nurse caring for a patient with CHF notes 2+ pitting edema in the lower extremities.
The priority intervention is:

A) Encourage ambulation

B) Administer diuretics as prescribed
C) Limit fluid intake

D) Apply warm compresses

Answer: B) Administer diuretics as prescribed

Rationale: Diuretics reduce fluid overload and edema, improving cardiac function.



2. A client with preeclampsia has BP 160/110 mmHg. The nurse should first:

A) Administer magnesium sulfate

B) Assess deep tendon reflexes

C) Call the healthcare provider immediately

D) Encourage rest

Answer: C) Call the healthcare provider immediately

Rationale: Severe hypertension in preeclampsia is an emergency requiring prompt
medical intervention.



3. A toddler with acute otitis media is prescribed amoxicillin. The nurse should:

A) Administer with food

B) Give only when symptomatic

C) Stop after fever subsides

D) Mix with juice to mask taste

Answer: A) Administer with food

Rationale: Reduces gastrointestinal upset and ensures proper absorption.

,4. A patient with schizophrenia hears voices telling them to harm themselves. Priority
nursing action:
A) Encourage distraction

B) Place on suicide precautions

C) Assess medication adherence

D) Call family

Answer: B) Place on suicide precautions

Rationale: Safety is the highest priority in psychiatric crises.



5. A nurse administers morphine IV and the patient’s respiratory rate drops to 8/min.
Immediate action:

A) Call the provider
B) Administer naloxone

C) Encourage deep breathing

D) Monitor closely

Answer: B) Administer naloxone

Rationale: Opioid-induced respiratory depression requires prompt reversal.



6. The first action when a patient develops anaphylaxis after penicillin administration is:

A) Administer diphenhydramine

B) Stop the infusion and call rapid response

C) Document the reaction

D) Apply cool compresses

Answer: B) Stop the infusion and call rapid response

Rationale: Immediate discontinuation and rapid intervention are life-saving.


7. A patient with COPD has oxygen at 2 L/min via nasal cannula. Priority assessment:

,A) Heart rate

B) Respiratory rate and effort

C) Blood pressure

D) Temperature

Answer: B) Respiratory rate and effort

Rationale: COPD patients are at risk of hypoxia or CO₂ retention; respiratory status is
critical.



8. A nurse teaches a diabetic patient to rotate injection sites. Reason:

A) Prevent lipodystrophy

B) Reduce infection risk

C) Enhance absorption

D) Decrease pain

Answer: A) Prevent lipodystrophy

Rationale: Rotation prevents tissue changes and ensures consistent absorption.



9. A patient on warfarin has an INR of 5.2. The nurse should:

A) Hold the dose and notify provider
B) Administer vitamin K immediately
C) Continue the dose

D) Recheck in 24 hours

Answer: A) Hold the dose and notify provider

Rationale: INR >5 increases bleeding risk; provider guidance is required.



10. Postoperative patient is at risk for DVT. Priority nursing intervention:

A) Encourage early ambulation

B) Apply heating pads

, C) Give analgesics

D) Restrict movement

Answer: A) Encourage early ambulation

Rationale: Early ambulation promotes venous return and prevents clot formation.



11. A patient with acute pancreatitis reports severe abdominal pain. The nurse should:

A) Administer prescribed IV opioids

B) Encourage oral intake
C) Apply cold compresses

D) Give antacids

Answer: A) Administer prescribed IV opioids

Rationale: Pain control is essential for comfort and to reduce sympathetic stress.



12. The priority nursing action for a patient with hypoglycemia (BS 45 mg/dL) is:

A) Administer oral glucose if conscious

B) Monitor vitals

C) Notify provider

D) Encourage rest

Answer: A) Administer oral glucose if conscious
Rationale: Rapid glucose correction prevents neurological complications.



13. A patient with UTI is prescribed ciprofloxacin. Important teaching:

A) Drink plenty of fluids
B) Take with dairy products

C) Avoid sunlight

D) Limit fluids

Answer: A) Drink plenty of fluids

Escuela, estudio y materia

Institución
Hesi
Grado
Hesi

Información del documento

Subido en
19 de septiembre de 2025
Número de páginas
61
Escrito en
2025/2026
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Examen
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