TEST BANK FOR Cellular and Molecular Immunology 10th Edition by Abul K. Abbas, Andrew H. Lichtman ISBN:978-0323757485 COMPLETE GUIDE ALL CHAPTERS COVERED 100 % VERIFIED A+ GRADE ASSURED !!!!! NEW LATEST UPDATE !!!!!

TEST BANK
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Cellular and Molecular Immunology
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Abul Abbas, Andrew Lichtman, and Shiv Pillai
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10th Edition
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,Table of Contents
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Chapter 01 Properties and Overview of Immune Responses
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Chapter 02 Cells and Tissues of the Immune System
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Chapter 03 Leukocyte Circulation and Migration Into Tissues
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Chapter 04 Innate Immunity
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Chapter 05 Antibodies and Antigens
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Chapter 06 Antigen Presentation to T Lymphocytes and the Functions of Major
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Histocompatibility Complex Molecules
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Chapter 07 Immune Receptors and Signal Transduction
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Chapter 08 Lymphocyte Development and Antigen Receptor Gene Rearrangement
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Chapter 09 Activation of T Lymphocytes
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Chapter 10 Differentiation and Functions of CD4+ Effector T Cells
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Chapter5% 11 Differentiation and Functions of CD8+ Effector T Cells
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Chapter5% 12 B Cell Activation and Antibody Production
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Chapter5% 13 Effector Mechanisms of Humoral Immunity
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Chapter5% 14 Specialized Immunity at Epithelial Barriers and in Immune Privileged Tissues
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Chapter5% 15 Immunologic Tolerance and Autoimmunity
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Chapter5% 16 Immunity to Microbes
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Chapter5% 17 Transplantation Immunology
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Chapter5% 18 Tumor Immunology
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Chapter 19 Hypersensitivity Disorders
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Chapter 20 Allergy
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Chapter 21 Primary and Acquired Immunodeficiencies
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,Chapter 01: Properties and Overview of Immune Responses
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Abbas, Lichtman, and Pillai: Cellular and Molecular Immunology, 10th Edition
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MULTIPLE CHOICE 5%




1. The principal function of the immune system is:
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a. Defense against cancer 5% 5%


b. Repair of injured tissues 5% 5% 5%


c. Defense against microbial infections 5% 5% 5%


d. Prevention of inflammatory diseases 5% 5% 5%


e. Protection against environmental toxins 5% 5% 5%




ANS: C 5 %


The immune system has evolved in the setting of selective pressures imposed by micr
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obial infections. Although immune responses to cancer may occur, the concept that “i
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mmunosurveillance” against cancer is a principal function of the immune system is c
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ontroversial. Repair of injured tissues may be a secondary consequence of the immun
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e responses and inflammation. Although the immune system has regulatory features t
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hat are needed to prevent excessive inflammation, prevention of inflammatory disease
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s is not a primary function. The immune system can protect against microbial toxins,
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but it generally does not offer protection against toxins of nonbiologic origin.
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2. Which of the following infectious diseases was prevented by the first succe
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ssful vaccination?
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a. Polio
b. Tuberculosis
c. Smallpox
d. Tetanus
e. Rubella
ANS: C 5 %


In 1798, Edward Jenner reported the first intentional successful vaccination, which w
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as against smallpox in a boy, using material from the cowpox pustules of a milkmaid.
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%In 1980, smallpox was reported to be eradicated worldwide by a vaccination progra
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m. Effective vaccines against tetanus toxin, rubella virus, and poliovirus were develop
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ed in the 20th century and are widely used. There is no effective vaccine against My
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cobacterium tuberculosis. 5%




3. Which of the following is a unique property of the adaptive immune system?
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a. Highly diverse repertoire of specificities for antigens
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b. Self-nonself discrimination 5%


c. Recognition of microbial structures by both cell-associated and soluble receptors
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d. Protection against viral infections 5% 5% 5%


e. Responses that have the same kinetics and magnitude on repeated exposure t
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o the same microbe
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ANS: 5 % A

, Highly diverse repertoires of specificities for antigens are found only in T and B lym
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phocytes, which are the central cellular components of the adaptive immune system.
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Both the innate and the adaptive immune systems use cell-
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associated and soluble receptors to recognize microbes, display some degree of self-
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nonself discrimination, and protect against viruses. On repeated exposure to the same
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microbe, the adaptive immune response becomes more rapid and of greater magnitude
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; this is the manifestation of memory.
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4. Antibodies and T lymphocytes are the respective mediators of which two typ
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es of immunity?
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a. Innate and adaptive 5% 5%


b. Passive and active 5% 5%


c. Specific and nonspecific 5% 5%


d. Humoral and cell-mediated 5% 5%


e. Adult and neonatal 5% 5%




ANS: D 5 %


Both B and T lymphocytes are principal components of adaptive immunity. B lympho
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cytes produce antibodies, which are the recognition and effector molecules of humoral
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%immune responses to extracellular pathogens. T cells recognize and promote eradicatio
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n of intracellular pathogens in cell-
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mediated immunity. Passive and active immunity both can be mediated by either B or
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T lymphocytes. Specific immunity is another term for adaptive immunity. Both B and
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T lymphocytes participate in adult adaptive immunity but are still developing in the n
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eonatal period. 5%




5. The two major functional classes of effector T lymphocytes are:
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a. Helper T lymphocytes and cytotoxic T lymphocytes
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b. Natural killer cells and cytoWtoWxW
ic.TTlB
yS
mMph.oW
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c. Memory T cells and effector T cells 5% 5% 5% 5% 5% 5%


d. Helper cells and antigen-presenting cells
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e. Cytotoxic T lymphocytes and target cells 5% 5% 5% 5% 5%




ANS: A 5 %


T cells can be classified into effector subsets that perform different effector functions.
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Most effector T cells are either helper T lymphocytes, which enhance the responses
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of other immune cells, including phagocytes and B cells, to infections, or cytotoxic T
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lymphocytes, which directly kill infected cells. Natural killer cells are not T lympho
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cytes.
Antigen-presenting cells usually are not T cells. Memory T cells are not effector T cells.
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6. Which of the following cell types is required for all adaptive humoral immune responses?
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a. Natural killer cells 5% 5%


b. Dendritic cells 5%


c. Cytolytic T lymphocytes 5% 5%


d. B lymphocytes 5%


e. Helper T lymphocytes 5% 5%




ANS: D 5 %


Humoral immune responses are antibody-
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mediated immune responses, and all antibodies are made by B lymphocytes and no
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other cell type.
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