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HESI Pharmacology Practice Test 2025-
26 | Comprehensive Key Questions With
Correct Answers
A client is diagnosed with peptic ulcer disease caused by Helicobacter pylori.
Which medications should the nurse anticipate the healthcare provider to
prescribe for the client? (select all that apply)
A. Clarithromycin (Biaxin)
B. Sulfisoxazole (Gantrisin)
C. Misoprostol (cytotec)
D. Omeprazole (Prilosec)
E. Metronidazole (Flagyl)
F. Sucralfate (Carafate)-correct-answer-A,D,E
The nurse is preparing to administer esomeprazole to a client for the management
of gastroesophageal reflux disease (GERD). Which finding in the client's history
should the nurse hold the medication and notify the healthcare provider?
A. Eats spicy food three times a week
B. treatment for deep vein thrombosis
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C. drinks 2 alcoholic beverages on weekends
D. Family history of diabetes mellitus-correct-answer-B
Which findings should the nurse identify in an adult client with possible chronic
salicylate intoxication?
A. tinnitus and hearing loss
B. Photosensitivity and nervousness
C Acute gastrointestinal bleeding and anorexia
D. Hyperventilation and central nervous system effects-correct-answer-A
A client receives a prescription for tetracycline (sumycin). Which instruction
should the nurse include in the client's teaching?
A. Take the medication with a glass of orange juice
B. Avoid over-the-counter medications containing alcohol
C. Avoid dairy products for 2 hours after taking the medication
D. Do not use teeth whitening agents during the treatment regimen-correct-
answer-C
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A client experiencing ventricular dysrhythmias is admitted to the intensive care
unit status post a myocardial infarction. The nurse should anticipate the
healthcare provider to prescribe which medication?
A. Diltiazem
B. Bretylium
C. Amiodarone
D. Adenosine-correct-answer-C
A client who is recently diagnosed with myasthenia gravis receives a prescription
for pyridostigmine (Mestinon), a cholinergic agent. Which information should the
nurse instruct the client to implement when taking this medication?
A. Always take with meals to avoid GI distress
B. Plan the doses close together for maximal therapeutic effect
C. Take the medication at least 30 minutes before eating meals
D. Avoid dairy products two hours before and after taking medications-correct-
answer-C
A mother of a child prescribed methylphenidate hydrochloride for attention-
deficit hyperactivity disorder (ADHD) informs the school nurse she administers the
medication at bedtime. Which instructions should the nurse recommend?
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A. continue administering the medication dose at bedtime
B. Give the medication when the child arrives at school
C. The medication should be taken with meals
D. Administer the medication t least 6 hours before bedtime-correct-answer-D
A client prescribed risperidone 10 mg/day for the past 3 months is being admitted
to the hospital. Which physical assessment findings should the nurse report to the
healthcare provider?
A anorexia
B. Drowsiness and lethargy
C. Tremors and muscle twitching
D. Dry mouth, and constipation-correct-answer-C
A client prescribed clindamycin hydrochloride intravenously asks the nurse why
blood has to be drawn before the third dose and one hour after the completion of
the administration of the medication. Which information should the nurse provide
the client to answer the question?
A. the onset action for the medication occurs very quickly
B. A small margin exists between safe and toxic plasma levels
C. Bioavailability is significantly reduced by the first-pass effect
D. Standard dosage is needed for the medication to be effective-correct-answer-B
HESI Pharmacology Practice Test 2025-
26 | Comprehensive Key Questions With
Correct Answers
A client is diagnosed with peptic ulcer disease caused by Helicobacter pylori.
Which medications should the nurse anticipate the healthcare provider to
prescribe for the client? (select all that apply)
A. Clarithromycin (Biaxin)
B. Sulfisoxazole (Gantrisin)
C. Misoprostol (cytotec)
D. Omeprazole (Prilosec)
E. Metronidazole (Flagyl)
F. Sucralfate (Carafate)-correct-answer-A,D,E
The nurse is preparing to administer esomeprazole to a client for the management
of gastroesophageal reflux disease (GERD). Which finding in the client's history
should the nurse hold the medication and notify the healthcare provider?
A. Eats spicy food three times a week
B. treatment for deep vein thrombosis
,2|Page
C. drinks 2 alcoholic beverages on weekends
D. Family history of diabetes mellitus-correct-answer-B
Which findings should the nurse identify in an adult client with possible chronic
salicylate intoxication?
A. tinnitus and hearing loss
B. Photosensitivity and nervousness
C Acute gastrointestinal bleeding and anorexia
D. Hyperventilation and central nervous system effects-correct-answer-A
A client receives a prescription for tetracycline (sumycin). Which instruction
should the nurse include in the client's teaching?
A. Take the medication with a glass of orange juice
B. Avoid over-the-counter medications containing alcohol
C. Avoid dairy products for 2 hours after taking the medication
D. Do not use teeth whitening agents during the treatment regimen-correct-
answer-C
,3|Page
A client experiencing ventricular dysrhythmias is admitted to the intensive care
unit status post a myocardial infarction. The nurse should anticipate the
healthcare provider to prescribe which medication?
A. Diltiazem
B. Bretylium
C. Amiodarone
D. Adenosine-correct-answer-C
A client who is recently diagnosed with myasthenia gravis receives a prescription
for pyridostigmine (Mestinon), a cholinergic agent. Which information should the
nurse instruct the client to implement when taking this medication?
A. Always take with meals to avoid GI distress
B. Plan the doses close together for maximal therapeutic effect
C. Take the medication at least 30 minutes before eating meals
D. Avoid dairy products two hours before and after taking medications-correct-
answer-C
A mother of a child prescribed methylphenidate hydrochloride for attention-
deficit hyperactivity disorder (ADHD) informs the school nurse she administers the
medication at bedtime. Which instructions should the nurse recommend?
, 4|Page
A. continue administering the medication dose at bedtime
B. Give the medication when the child arrives at school
C. The medication should be taken with meals
D. Administer the medication t least 6 hours before bedtime-correct-answer-D
A client prescribed risperidone 10 mg/day for the past 3 months is being admitted
to the hospital. Which physical assessment findings should the nurse report to the
healthcare provider?
A anorexia
B. Drowsiness and lethargy
C. Tremors and muscle twitching
D. Dry mouth, and constipation-correct-answer-C
A client prescribed clindamycin hydrochloride intravenously asks the nurse why
blood has to be drawn before the third dose and one hour after the completion of
the administration of the medication. Which information should the nurse provide
the client to answer the question?
A. the onset action for the medication occurs very quickly
B. A small margin exists between safe and toxic plasma levels
C. Bioavailability is significantly reduced by the first-pass effect
D. Standard dosage is needed for the medication to be effective-correct-answer-B
