WGU 785 Final Exam 2026 Questions
and Answers
Hemophilia Pedigree - Father has hemophilia, mother does not. What is the
outcome for their kids? - Correct answer-His daughters would be carriers. This is
x-link recessive.
Autosomal:
Dominant: - Correct answer-Autosomal: males and females equally affected.
Dominant: non-carrier parents
polymerase chain reaction (PCR) - Correct answer-The process of copying DNA in
the lab. Uses Template DNA, Nucleotides (dNTPS), DNA Polymerase, and DNA
primers.
3 Steps of PCR - Correct answer-1. Denaturation: DNA is heated to 95C to
separate it.
2. Annealing: reaction is cooled to 50C; primers stick to the DNA you want to copy
and add DNA polymerase.
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,3. Elongation: reaction heated to 70C and DNA polymerase, adding nucleotides
building a new DNA strand.
Base Excision Repair (BER) - Correct answer-How you repair a mutation. BER is
used to repair damage to a base caused by harmful molecules. You remove the base
that is damaged and replace it. *BER removes a single nucleotide*
DNA glycolsylase - sees damaged DNA and removes it.
DNA polymerase-puts the right one back in while DNA ligase seals it.
Mismatch repair (MMR) occurs during: - Correct answer-replication. DNA
polymerase proofreads but sometimes a mismatch pair gets through. MMR
removes a large section of the nucleotides from the new DNA and DNA
polymerase tries again. (Ex: C-T instead of C-A)
Mismatch Repair corrects what kind of DNA damage? - Correct answer-When a
base is mismatched due to errors in replication. Such as G-T instead of G-C. DNA
polymerase comes by and fixes it.
What happens when DNA polymerase binds to DNA to make RNA? - Correct
answer-TRANSCRIPTION! DNA polymerase takes the individual nucleotides and
matches them to the parental sequences to ensure a correct pair. It must bind with
RNA primer to work.
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, What is needed for DNA replication? - Correct answer-DNA polymerase
Nonsense Mutation - Correct answer-Change in 1 nucleotide produces a STOP
codon Stop= nonsense because it is no more.
Silent Mutation - Correct answer-Change in 1 nucleotide but codes for the same
amino acid. Silent= the change doesn't change the name of the protein
Missense Mutation - Correct answer-Change in 1 nucleotide leads to a code for a
different amino acid. Missense = mistake was made.
What happends during RNA splicing? - Correct answer-During RNA splicing
introns are cut out, the remaining exons are joined together.
5'ATG AGT CTC TCT 3'
Find the DNA template strand. - Correct answer-3'TAC TCA GAG AGA 5'
The DNA template strand is complimentary. So start with the opposite number,
then go L-R with the complimentary letter.
5'ATG AGT CTC TCT 3'
What is the corresonding mRNA sequence? - Correct answer-5'AUG AGU CUC
UCU 3'
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and Answers
Hemophilia Pedigree - Father has hemophilia, mother does not. What is the
outcome for their kids? - Correct answer-His daughters would be carriers. This is
x-link recessive.
Autosomal:
Dominant: - Correct answer-Autosomal: males and females equally affected.
Dominant: non-carrier parents
polymerase chain reaction (PCR) - Correct answer-The process of copying DNA in
the lab. Uses Template DNA, Nucleotides (dNTPS), DNA Polymerase, and DNA
primers.
3 Steps of PCR - Correct answer-1. Denaturation: DNA is heated to 95C to
separate it.
2. Annealing: reaction is cooled to 50C; primers stick to the DNA you want to copy
and add DNA polymerase.
©COPYRIGHT 2025, ALL RIGHTS RESERVE 1
,3. Elongation: reaction heated to 70C and DNA polymerase, adding nucleotides
building a new DNA strand.
Base Excision Repair (BER) - Correct answer-How you repair a mutation. BER is
used to repair damage to a base caused by harmful molecules. You remove the base
that is damaged and replace it. *BER removes a single nucleotide*
DNA glycolsylase - sees damaged DNA and removes it.
DNA polymerase-puts the right one back in while DNA ligase seals it.
Mismatch repair (MMR) occurs during: - Correct answer-replication. DNA
polymerase proofreads but sometimes a mismatch pair gets through. MMR
removes a large section of the nucleotides from the new DNA and DNA
polymerase tries again. (Ex: C-T instead of C-A)
Mismatch Repair corrects what kind of DNA damage? - Correct answer-When a
base is mismatched due to errors in replication. Such as G-T instead of G-C. DNA
polymerase comes by and fixes it.
What happens when DNA polymerase binds to DNA to make RNA? - Correct
answer-TRANSCRIPTION! DNA polymerase takes the individual nucleotides and
matches them to the parental sequences to ensure a correct pair. It must bind with
RNA primer to work.
©COPYRIGHT 2025, ALL RIGHTS RESERVE 2
, What is needed for DNA replication? - Correct answer-DNA polymerase
Nonsense Mutation - Correct answer-Change in 1 nucleotide produces a STOP
codon Stop= nonsense because it is no more.
Silent Mutation - Correct answer-Change in 1 nucleotide but codes for the same
amino acid. Silent= the change doesn't change the name of the protein
Missense Mutation - Correct answer-Change in 1 nucleotide leads to a code for a
different amino acid. Missense = mistake was made.
What happends during RNA splicing? - Correct answer-During RNA splicing
introns are cut out, the remaining exons are joined together.
5'ATG AGT CTC TCT 3'
Find the DNA template strand. - Correct answer-3'TAC TCA GAG AGA 5'
The DNA template strand is complimentary. So start with the opposite number,
then go L-R with the complimentary letter.
5'ATG AGT CTC TCT 3'
What is the corresonding mRNA sequence? - Correct answer-5'AUG AGU CUC
UCU 3'
©COPYRIGHT 2025, ALL RIGHTS RESERVE 3
