BIOC 385 Exam 2 Question Set with
complete solutions passed
Glycogen - correct answer ✔✔Which glucose homopolymer would be used if a person had to
sprint quickly?
Glycogen synthesis - correct answer ✔✔Gluconeogenesis would most likely be allosterically
activated simultaneously along with which other metabolic process?
Glucagon - correct answer ✔✔Which hormone slows down glycolysis while stimulating
gluconeogenesis through the phosphorylation of phosphofructokinase 2 (PFK2) and fructose-
2,6-bisphosphatase?
NADP+ - correct answer ✔✔What molecule activates the pentose phosphate pathway?
activated by ATP energy - correct answer ✔✔In the reaction catalyzed by pyruvate carboxylase
(the first reaction in gluconeogenesis), CO2 is
0; 2 - correct answer ✔✔Starting from the oxidative phase of the pentose phosphate pathway,
how many ATP and high-energy reduced molecules, respectively, are made in going from one
glucose molecule to glyceraldehyde-3-phosphate and fructose-6-phosphate?
glycerol - correct answer ✔✔Which of the following metabolites has carbon atoms that can end
up in glucose via the gluconeogenesis pathway in humans?
increase; glycolysis - correct answer ✔✔The hormone insulin activates phosphofructokinase 2
(2PFK2). This leads to a(n) __________ in concentration of fructose 2,6 bisphosphate, which
favors the __________ pathway.
, It provides a source of NADH for gluconeogenesis via malate transport. - correct answer
✔✔Which correctly describes the role of the transport system shown below?
Glucose is not exported from muscle cells because muscle cells lack glucose-6-phosphatase. -
correct answer ✔✔How does glycogen metabolism regulation differ between liver cells and
muscle cells?
Muscle cells store glycogen for its own energy needs and not the needs of other tissues. -
correct answer ✔✔Why is it important that muscle cells are unresponsive to glucagon?
serve as the origin of the glycogen polymer. - correct answer ✔✔The role of glycogenin is to
glycogen synthase; glycogen phosphorylase; decrease - correct answer ✔✔The hormone insulin
stimulates __________ and inhibits __________, leading to a(n) __________ in the glucose
levels.
C-4 - correct answer ✔✔In the elongation of glycogen, activated glucose units are attached to
which hydroxyl of the terminal residue of the growing glycogen chain?
a) [Pi]/[glucose 1-phosphate] = 3.5/1
b) The concentration of glucose 1-phosphate is below the equilibrium value. Therefore, the rate
of glucose 1-phosphate removal (through entry into glycolysis) is greater than the rate at which
glucose 1-phosphate is produced by glycogen phosphorylase, so metabolite flow is from
glycogen to glucose 1-phosphate. - correct answer ✔✔Glycogen phosphorylase catalyzes the
removal of glucose from glycogen. The ΔGo' for this reaction is 3.1 kJ/mol.
a) Calculate the ratio of [Pi] to [glucose 1-phosphate] when the reaction is at equilibrium at
298K. (Hint: the removal of glucose units from glycogen does not change the glycogen
concentration.)
complete solutions passed
Glycogen - correct answer ✔✔Which glucose homopolymer would be used if a person had to
sprint quickly?
Glycogen synthesis - correct answer ✔✔Gluconeogenesis would most likely be allosterically
activated simultaneously along with which other metabolic process?
Glucagon - correct answer ✔✔Which hormone slows down glycolysis while stimulating
gluconeogenesis through the phosphorylation of phosphofructokinase 2 (PFK2) and fructose-
2,6-bisphosphatase?
NADP+ - correct answer ✔✔What molecule activates the pentose phosphate pathway?
activated by ATP energy - correct answer ✔✔In the reaction catalyzed by pyruvate carboxylase
(the first reaction in gluconeogenesis), CO2 is
0; 2 - correct answer ✔✔Starting from the oxidative phase of the pentose phosphate pathway,
how many ATP and high-energy reduced molecules, respectively, are made in going from one
glucose molecule to glyceraldehyde-3-phosphate and fructose-6-phosphate?
glycerol - correct answer ✔✔Which of the following metabolites has carbon atoms that can end
up in glucose via the gluconeogenesis pathway in humans?
increase; glycolysis - correct answer ✔✔The hormone insulin activates phosphofructokinase 2
(2PFK2). This leads to a(n) __________ in concentration of fructose 2,6 bisphosphate, which
favors the __________ pathway.
, It provides a source of NADH for gluconeogenesis via malate transport. - correct answer
✔✔Which correctly describes the role of the transport system shown below?
Glucose is not exported from muscle cells because muscle cells lack glucose-6-phosphatase. -
correct answer ✔✔How does glycogen metabolism regulation differ between liver cells and
muscle cells?
Muscle cells store glycogen for its own energy needs and not the needs of other tissues. -
correct answer ✔✔Why is it important that muscle cells are unresponsive to glucagon?
serve as the origin of the glycogen polymer. - correct answer ✔✔The role of glycogenin is to
glycogen synthase; glycogen phosphorylase; decrease - correct answer ✔✔The hormone insulin
stimulates __________ and inhibits __________, leading to a(n) __________ in the glucose
levels.
C-4 - correct answer ✔✔In the elongation of glycogen, activated glucose units are attached to
which hydroxyl of the terminal residue of the growing glycogen chain?
a) [Pi]/[glucose 1-phosphate] = 3.5/1
b) The concentration of glucose 1-phosphate is below the equilibrium value. Therefore, the rate
of glucose 1-phosphate removal (through entry into glycolysis) is greater than the rate at which
glucose 1-phosphate is produced by glycogen phosphorylase, so metabolite flow is from
glycogen to glucose 1-phosphate. - correct answer ✔✔Glycogen phosphorylase catalyzes the
removal of glucose from glycogen. The ΔGo' for this reaction is 3.1 kJ/mol.
a) Calculate the ratio of [Pi] to [glucose 1-phosphate] when the reaction is at equilibrium at
298K. (Hint: the removal of glucose units from glycogen does not change the glycogen
concentration.)
