BIOC 385 Exam 2 (Summer) questions
well answered passed
Which one of the following is involved in the breakdown of glycogen? - correct answer
✔✔inorganic phosphate
Which enzyme catalyzes the formation of alpha(1,6) linkages during glycogen synthesis? -
correct answer ✔✔branching enzyme
The activation of glycogen phosphorylase will lead to a(n) ____ in blood glucose concentrations
and is stimulated by the hormone _____. - correct answer ✔✔increase; glucagon
Because muscles lack receptors for glucagon, what hormone activates muscle glycogen
phosphorylase? - correct answer ✔✔epinephrine
Chylomicrons contain a monolayer on the outside of the particle consisting of ___________. -
correct answer ✔✔phospholipids and cholesterol
The lipase-mediated release of fatty acids can always be expected to occur when a person is
___________ and ___________. (Choose the best two answers) - correct answer ✔✔running
from a bear, hungry after school
In comparison with glycerophospholipids, the structure of cerebrosides contains ________ . -
correct answer ✔✔sphingosine
Tay-Sachs disease, Fabry disease, and Niemann-Pick disease are all symptomatic because of
___________ . - correct answer ✔✔defects in sphingolipid metabolism
,A patient is having problems regulating blood pressure and has poor kidney function. Which
steroid could be responsible for this? - correct answer ✔✔aldosterone
Inhibition of the COX-1 enzyme results in - correct answer ✔✔reduced mucin, secretion in the
stomach
The enzyme ___________ primes fatty acids in the cytosol so they can be degraded in the
mitochondrial matrix. The enzyme ____________ catalyzes the modification of fatty acyl-CoA
derivatives so they can be transported into the mitochondrial matrix. The enzyme _________
generates palmitate from malonyl-CoA. Choose the best answer below. - correct answer
✔✔fatty acyl-CoA synthetase; carnitine acyltransferase I; fatty acid synthase
How many moles of acetyl-CoA, FADH2 and NADH are generated by beta-oxidation of one mole
of the fatty acid myristate? - correct answer ✔✔7 acetyle CoA, 6 NADH, 6 FADH2
What molecule is the odd chain fatty acid product propionyl-CoA converted into? - correct
answer ✔✔succinyl CoA
Which of the following are ketone bodies? - correct answer ✔✔hydroxybutyrate, acetoacetate
What cofactor, common to carboxylase enzymes, is used by acetyl-CoA carboxylase? - correct
answer ✔✔Biotin
What are the different roles played the acyl carrier protein (ACP) and the ketoacyl synthase (KS)
domain during fatty acid synthesis? - correct answer ✔✔The ACP carries the growing fatty acid
chain more than the KS domain.
Which step is required for the synthesis of phosphatidylethanolamine? - correct answer
✔✔phosphatidylserine is decarboxylated
, Which of the following causes inhibition of fatty acid synthesis? - correct answer ✔✔increased
AMP-activated protein kinase activity
Which enzyme catalyzes the rate-limiting step of cholesterol synthesis? - correct answer
✔✔(HMG-CoA) reductase
Which one of the following lipoproteins functions to transport cholesterol from the peripheral
tissues to the liver? - correct answer ✔✔HDL
What are the four key enzymes in nitrogen fixation and assimilation in plants and bacteria? -
correct answer ✔✔nitrogenase complex, glutamine synthetase, plutamate synthase, glutamata
dehydrogenase
Which of the following is the correct net reaction for the combined reaction of glutamine
synthetase and glutamate synthase? - correct answer ✔✔ketoglutarate + NH4++ ATP + NADH +
H+NAD++ ADP + Pi+ glutamate
What is a Benefit, and what is a Risk, of using a COX-2 selective inhibitor to treat inflammation?
Exam 2 - correct answer ✔✔Benefit: decreased inflammation; Risk: increased cardiovascular
problems
How is glycogen phosphorylase allosterically activated in muscle cells?
Exam 2 - correct answer ✔✔Glycogen phosphorylase is shifted to R state by binding of AMP
What are the total number of moles of Acetyl CoA, NADH, and FADH2 resulting from the
complete oxidation of one mole of a fatty acid with the molecular formula C18H35O2 , and
what is its common name?
Exam 2 - correct answer ✔✔9 Acetyl CoA, 8 NADH, 8 FADH2; stearate
well answered passed
Which one of the following is involved in the breakdown of glycogen? - correct answer
✔✔inorganic phosphate
Which enzyme catalyzes the formation of alpha(1,6) linkages during glycogen synthesis? -
correct answer ✔✔branching enzyme
The activation of glycogen phosphorylase will lead to a(n) ____ in blood glucose concentrations
and is stimulated by the hormone _____. - correct answer ✔✔increase; glucagon
Because muscles lack receptors for glucagon, what hormone activates muscle glycogen
phosphorylase? - correct answer ✔✔epinephrine
Chylomicrons contain a monolayer on the outside of the particle consisting of ___________. -
correct answer ✔✔phospholipids and cholesterol
The lipase-mediated release of fatty acids can always be expected to occur when a person is
___________ and ___________. (Choose the best two answers) - correct answer ✔✔running
from a bear, hungry after school
In comparison with glycerophospholipids, the structure of cerebrosides contains ________ . -
correct answer ✔✔sphingosine
Tay-Sachs disease, Fabry disease, and Niemann-Pick disease are all symptomatic because of
___________ . - correct answer ✔✔defects in sphingolipid metabolism
,A patient is having problems regulating blood pressure and has poor kidney function. Which
steroid could be responsible for this? - correct answer ✔✔aldosterone
Inhibition of the COX-1 enzyme results in - correct answer ✔✔reduced mucin, secretion in the
stomach
The enzyme ___________ primes fatty acids in the cytosol so they can be degraded in the
mitochondrial matrix. The enzyme ____________ catalyzes the modification of fatty acyl-CoA
derivatives so they can be transported into the mitochondrial matrix. The enzyme _________
generates palmitate from malonyl-CoA. Choose the best answer below. - correct answer
✔✔fatty acyl-CoA synthetase; carnitine acyltransferase I; fatty acid synthase
How many moles of acetyl-CoA, FADH2 and NADH are generated by beta-oxidation of one mole
of the fatty acid myristate? - correct answer ✔✔7 acetyle CoA, 6 NADH, 6 FADH2
What molecule is the odd chain fatty acid product propionyl-CoA converted into? - correct
answer ✔✔succinyl CoA
Which of the following are ketone bodies? - correct answer ✔✔hydroxybutyrate, acetoacetate
What cofactor, common to carboxylase enzymes, is used by acetyl-CoA carboxylase? - correct
answer ✔✔Biotin
What are the different roles played the acyl carrier protein (ACP) and the ketoacyl synthase (KS)
domain during fatty acid synthesis? - correct answer ✔✔The ACP carries the growing fatty acid
chain more than the KS domain.
Which step is required for the synthesis of phosphatidylethanolamine? - correct answer
✔✔phosphatidylserine is decarboxylated
, Which of the following causes inhibition of fatty acid synthesis? - correct answer ✔✔increased
AMP-activated protein kinase activity
Which enzyme catalyzes the rate-limiting step of cholesterol synthesis? - correct answer
✔✔(HMG-CoA) reductase
Which one of the following lipoproteins functions to transport cholesterol from the peripheral
tissues to the liver? - correct answer ✔✔HDL
What are the four key enzymes in nitrogen fixation and assimilation in plants and bacteria? -
correct answer ✔✔nitrogenase complex, glutamine synthetase, plutamate synthase, glutamata
dehydrogenase
Which of the following is the correct net reaction for the combined reaction of glutamine
synthetase and glutamate synthase? - correct answer ✔✔ketoglutarate + NH4++ ATP + NADH +
H+NAD++ ADP + Pi+ glutamate
What is a Benefit, and what is a Risk, of using a COX-2 selective inhibitor to treat inflammation?
Exam 2 - correct answer ✔✔Benefit: decreased inflammation; Risk: increased cardiovascular
problems
How is glycogen phosphorylase allosterically activated in muscle cells?
Exam 2 - correct answer ✔✔Glycogen phosphorylase is shifted to R state by binding of AMP
What are the total number of moles of Acetyl CoA, NADH, and FADH2 resulting from the
complete oxidation of one mole of a fatty acid with the molecular formula C18H35O2 , and
what is its common name?
Exam 2 - correct answer ✔✔9 Acetyl CoA, 8 NADH, 8 FADH2; stearate
