NRSG 3100 Unit 5 Questions With Complete Solutions
Acyclovir (Zovirax) Adverse Effects Correct Answer Few
adverse effects when given PO or topically
Nausea, vomiting, anorexia, elevated hepatic enzymes
Minor skin irritation
Nephrotoxicity - IV route
Administer IV dose slowly, ensure patient is hydrated
Neurotoxicity also reported at high IV doses (dizziness,
confusion, delirium, coma)
Acyclovir (Zovirax) Contraindications/Precautions Correct
Answer Use with caution in patients with renal impairment-
excreted by the kidneys
Acyclovir (Zovirax) Drug Interactions Correct Answer
Probenecid (gout) - decreases elimination that can lead to toxic
levels of the antiviral
Nephrotoxicity - if used with drugs affecting renal function
Acyclovir (Zovirax) Indications Correct Answer Drug of
choice for herpes virus
Prophylaxis use decreases recurrences, not a cure
Acyclovir (Zovirax) Patient Education Correct Answer Even
though the virus may be controlled, the latent virus can be
activated by stress, trauma, fever, exposure to sunlight, sex,
menstruation, or treatment with immunosuppressants
Amantadine (Symmetrel) Adverse Effects Correct Answer
CNS effects - insomnia, dizziness, light-headedness,
, nervousness, loss of concentration, and mental confusion - in up
to 33%
Psychiatric disorders or substance abuse patients - can worsen
mental problems
Renal impaired patients - drug can build to toxic levels
Resulting in visual or auditory hallucinations, seizures, coma, or
dysrhythmias.
Older adults - higher incidence of adverse effects
Amantadine (Symmetrel) Contraindications/Precautions
Correct Answer Use cautiously in patients: CNS disease,
preexisting renal disease, preexisting cardiac disease
Patients with Parkingson's disease - do not abruptly withdraw -
Parkinson's symptoms may worsen
Amantadine (Symmetrel) Drug Interactions Correct Answer
Avoid alcohol - may lead to increased CNS toxicity
Anticholinergic drugs will have additive effect
Dopamine antagonists will reduce the antiparkinson effects
Amantadine (Symmetrel) Indications Correct Answer
Influenza antiviral -therapeutic and prophylactic uses
Not a substitute for influenza virus vaccination
For patients at high risk for influenza exposure
immunocompromised, long-term care residents, health care
workers, close personal contacts of high-risk patients
Has anticholoinergic effects - can benefit patients with
Parkinson's disease - not a major drug for this disorder
Amphotericin B Deoxycholate (Fungizone) Adverse Effects
Correct Answer Up to 50% experience fever, chills, vomiting,
Acyclovir (Zovirax) Adverse Effects Correct Answer Few
adverse effects when given PO or topically
Nausea, vomiting, anorexia, elevated hepatic enzymes
Minor skin irritation
Nephrotoxicity - IV route
Administer IV dose slowly, ensure patient is hydrated
Neurotoxicity also reported at high IV doses (dizziness,
confusion, delirium, coma)
Acyclovir (Zovirax) Contraindications/Precautions Correct
Answer Use with caution in patients with renal impairment-
excreted by the kidneys
Acyclovir (Zovirax) Drug Interactions Correct Answer
Probenecid (gout) - decreases elimination that can lead to toxic
levels of the antiviral
Nephrotoxicity - if used with drugs affecting renal function
Acyclovir (Zovirax) Indications Correct Answer Drug of
choice for herpes virus
Prophylaxis use decreases recurrences, not a cure
Acyclovir (Zovirax) Patient Education Correct Answer Even
though the virus may be controlled, the latent virus can be
activated by stress, trauma, fever, exposure to sunlight, sex,
menstruation, or treatment with immunosuppressants
Amantadine (Symmetrel) Adverse Effects Correct Answer
CNS effects - insomnia, dizziness, light-headedness,
, nervousness, loss of concentration, and mental confusion - in up
to 33%
Psychiatric disorders or substance abuse patients - can worsen
mental problems
Renal impaired patients - drug can build to toxic levels
Resulting in visual or auditory hallucinations, seizures, coma, or
dysrhythmias.
Older adults - higher incidence of adverse effects
Amantadine (Symmetrel) Contraindications/Precautions
Correct Answer Use cautiously in patients: CNS disease,
preexisting renal disease, preexisting cardiac disease
Patients with Parkingson's disease - do not abruptly withdraw -
Parkinson's symptoms may worsen
Amantadine (Symmetrel) Drug Interactions Correct Answer
Avoid alcohol - may lead to increased CNS toxicity
Anticholinergic drugs will have additive effect
Dopamine antagonists will reduce the antiparkinson effects
Amantadine (Symmetrel) Indications Correct Answer
Influenza antiviral -therapeutic and prophylactic uses
Not a substitute for influenza virus vaccination
For patients at high risk for influenza exposure
immunocompromised, long-term care residents, health care
workers, close personal contacts of high-risk patients
Has anticholoinergic effects - can benefit patients with
Parkinson's disease - not a major drug for this disorder
Amphotericin B Deoxycholate (Fungizone) Adverse Effects
Correct Answer Up to 50% experience fever, chills, vomiting,
