,Test Bank Rubin's Pathology: Clinicopathologic Foundations of Medicine 7th Edition
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Table of Contents:
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Chapter 1: Cell Adaptation, Injury and Death
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Chapter 2: Inflammation
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Chapter 3: Repair, Regeneration and Fibrosis
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Chapter 4: Immunopathology
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Chapter 5: Neoplasia
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Chapter 6: Developmental and Genetic Diseases
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Chapter 7: Hemodynamic Disorders
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Chapter 8: Environmental and Nutritional Pathology
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Chapter 9: Infectious and Parasitic Diseases
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Section II: Pathogenesis of Systemic Conditions Expandable section
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Chapter 10: Aging
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Chapter 11: Systemic Autoimmune Diseases
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Chapter 12: Sepsis
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Chapter 13: Obesity and Diabetes Mellitus
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Chapter 14: The Pathology of Pregnancy
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Chapter 15: The Amyloidoses
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Section III: Diseases of Individual Organ SystemsExpandable section
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Chapter 16: Blood Vessels
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Chapter 17: The Heart
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Chapter 18: The Respiratory System
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Chapter 19: The Gastrointestinal Tract
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Chapter 20: The Liver and Biliary System
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Chapter 21: The Pancreas
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Chapter 22: The Kidney
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Chapter 23: The Lower Urinary Tract and Male Reproductive System
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Chapter 24: The Female Reproductive System and Peritoneum
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Chapter 25: The Breast
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Chapter 26: Hematopathology
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Chapter 27: The Endocrine System
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Chapter 28: The Skin
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Chapter 29: The Head and Neck
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Chapter 30: Bones, Joints and Soft Tissue
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Chapter 31: Skeletal Muscle and Peripheral Nervous System
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Chapter 32: The Central Nervous System
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Chapter 33: The Eye
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Chapter 34: Forensic Pathology
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,Rubin's Pathology: Clinicopathologic Foundations of Medicine
ku ku ku ku ku
Chapter 1: Cell Adaptation, Injury and Death
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Ischemia and other toxic injuries increase the accumulation of intracellular calcium as a
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1. result of:
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A) release of stored calcium from the mitochondria.
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B) improved intracellular volume regulation.
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C) decreased influx across the cell membrane.
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D) attraction of calcium to fatty infiltrates.
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The patient is found to have liver disease, resulting in the removal of a lobe of his
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2. liver. Adaptation to the reduced size of the liver leads to _ of the remaining liver
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cells.
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A) metaplasia
B) organ atrophy ku
C) compensatory hyperplasia ku
D) physiologic hypertrophy ku
A person eating peanuts starts choking and collapses. His airway obstruction is
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partially cleared, but he remains hypoxic until he reaches the hospital. The
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3. prolonged cell hypoxia caused a cerebral infarction and resulting
ku ku ku _ in the brain. ku ku ku ku ku ku ku ku ku
A) caspase activation ku
B) coagulation necrosis ku
C) rapid phagocytosis
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D) protein p53 deficiency ku ku
Bacteria and viruses cause cell damage by
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4. intracellular damage caused by other injurious agents.
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A) disrupting the sodium/potassium ATPase pump
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B) interrupting oxidative metabolism processes ku ku ku
C) replicating and producing continued injury ku ku ku ku
D) decreasing protein synthesis and function ku ku ku ku
The patient has a prolonged interruption in arterial blood flow to his left kidney, causing
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5. hypoxic cell injury and the release of free radicals. Free radicals damage cells by:
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A) destroying phospholipids in the cell membrane.
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B) altering the immune response of the cell.
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C) disrupting calcium storage in the cell. ku ku ku ku ku
, D) inactivation of enzymes and mitochondria. ku ku ku ku
6. Injured cells have impaired flow of substances through the cell membrane as a result of:
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A) increased fat load. ku ku
B) altered permeability. ku
C) altered glucose utilization. ku ku
D) increased surface receptors. ku ku
7. Reversible adaptive intracellular responses are initiated by:
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A) stimulus overload. ku
B) genetic mutations. ku
C) chemical messengers. ku
D) mitochondrial DNA. ku
8. Injured cells become very swollen as a result of:
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A) increased cell protein synthesis. ku ku ku
B) altered cell volume regulation.
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C) passive entry of potassium into the cell.
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D) bleb formation in the plasma membrane.
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A diabetic patient has impaired sensation, circulation, and oxygenation of his feet. He
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steps on a piece of glass, the wound does not heal, and the area tissue becomes
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9. necrotic. The necrotic cell death is characterized by:
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A) rapid apoptosis. ku
B) cellular rupture. ku
C) shrinkage and collapse. ku ku
D) chronic inflammation. ku
A 99-year-old woman has experienced the decline of cell function associated with age. A
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10. group of theories of cellular aging focus on programmed:
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A) changes with genetic influences. ku ku ku
B) elimination of cell receptor sites. ku ku ku ku
C) insufficient telomerase enzyme. ku ku
D) DNA mutation or faulty repair.
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An 89-year-old female patient has experienced significant decreases in her mobility and
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stamina during a 3-week hospital stay for the treatment of a femoral head fracture.
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Which of the following phenomena most likely accounts for the patients decrease in
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11. muscle function that underlies her reduced mobility?
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A) Impaired muscle cell metabolism resulting from metaplasia
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ku ku ku ku ku ku ku ku
ku
Table of Contents:
ku ku
Chapter 1: Cell Adaptation, Injury and Death
ku ku ku ku ku ku
Chapter 2: Inflammation
ku ku
Chapter 3: Repair, Regeneration and Fibrosis
ku ku ku ku ku
Chapter 4: Immunopathology
ku ku
Chapter 5: Neoplasia
ku ku
Chapter 6: Developmental and Genetic Diseases
ku ku ku ku ku
Chapter 7: Hemodynamic Disorders
ku ku ku
Chapter 8: Environmental and Nutritional Pathology
ku ku ku ku ku
Chapter 9: Infectious and Parasitic Diseases
ku ku ku ku ku
Section II: Pathogenesis of Systemic Conditions Expandable section
ku ku ku ku ku ku ku
Chapter 10: Aging
ku ku
Chapter 11: Systemic Autoimmune Diseases
ku ku ku ku
Chapter 12: Sepsis
ku ku
Chapter 13: Obesity and Diabetes Mellitus
ku ku ku ku ku
Chapter 14: The Pathology of Pregnancy
ku ku ku ku ku
Chapter 15: The Amyloidoses
ku ku ku
Section III: Diseases of Individual Organ SystemsExpandable section
ku ku ku ku ku ku ku
Chapter 16: Blood Vessels
ku ku ku
Chapter 17: The Heart
ku ku ku
Chapter 18: The Respiratory System
ku ku ku ku
Chapter 19: The Gastrointestinal Tract
ku ku ku ku
Chapter 20: The Liver and Biliary System
ku ku ku ku ku ku
Chapter 21: The Pancreas
ku ku ku
Chapter 22: The Kidney
ku ku ku
Chapter 23: The Lower Urinary Tract and Male Reproductive System
ku ku ku ku ku ku ku ku ku
Chapter 24: The Female Reproductive System and Peritoneum
ku ku ku ku ku ku ku
Chapter 25: The Breast
ku ku ku
Chapter 26: Hematopathology
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Chapter 27: The Endocrine System
ku ku ku ku
Chapter 28: The Skin
ku ku ku
Chapter 29: The Head and Neck
ku ku ku ku ku
Chapter 30: Bones, Joints and Soft Tissue
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Chapter 31: Skeletal Muscle and Peripheral Nervous System
ku ku ku ku ku ku ku
Chapter 32: The Central Nervous System
ku ku ku ku ku
Chapter 33: The Eye
ku ku ku
Chapter 34: Forensic Pathology
ku ku ku
,Rubin's Pathology: Clinicopathologic Foundations of Medicine
ku ku ku ku ku
Chapter 1: Cell Adaptation, Injury and Death
ku ku ku ku ku ku ku
Ischemia and other toxic injuries increase the accumulation of intracellular calcium as a
ku ku ku ku ku ku ku ku ku ku ku ku
1. result of:
ku ku
A) release of stored calcium from the mitochondria.
ku ku ku ku ku ku
B) improved intracellular volume regulation.
ku ku ku
C) decreased influx across the cell membrane.
ku ku ku ku ku
D) attraction of calcium to fatty infiltrates.
ku ku ku ku ku
The patient is found to have liver disease, resulting in the removal of a lobe of his
ku ku ku ku ku ku ku ku ku ku ku ku ku ku ku ku
2. liver. Adaptation to the reduced size of the liver leads to _ of the remaining liver
ku ku ku ku ku ku ku ku ku ku ku ku ku ku ku
cells.
ku
A) metaplasia
B) organ atrophy ku
C) compensatory hyperplasia ku
D) physiologic hypertrophy ku
A person eating peanuts starts choking and collapses. His airway obstruction is
ku ku ku ku ku ku ku ku ku ku ku
partially cleared, but he remains hypoxic until he reaches the hospital. The
ku ku ku ku ku ku ku ku ku ku ku ku
3. prolonged cell hypoxia caused a cerebral infarction and resulting
ku ku ku _ in the brain. ku ku ku ku ku ku ku ku ku
A) caspase activation ku
B) coagulation necrosis ku
C) rapid phagocytosis
ku
D) protein p53 deficiency ku ku
Bacteria and viruses cause cell damage by
ku ku , which is unique from the ku ku ku ku ku ku ku ku ku
4. intracellular damage caused by other injurious agents.
ku ku ku ku ku ku ku
A) disrupting the sodium/potassium ATPase pump
ku ku ku ku
B) interrupting oxidative metabolism processes ku ku ku
C) replicating and producing continued injury ku ku ku ku
D) decreasing protein synthesis and function ku ku ku ku
The patient has a prolonged interruption in arterial blood flow to his left kidney, causing
ku ku ku ku ku ku ku ku ku ku ku ku ku ku
5. hypoxic cell injury and the release of free radicals. Free radicals damage cells by:
ku ku ku ku ku ku ku ku ku ku ku ku ku ku
A) destroying phospholipids in the cell membrane.
ku ku ku ku ku
B) altering the immune response of the cell.
ku ku ku ku ku ku
C) disrupting calcium storage in the cell. ku ku ku ku ku
, D) inactivation of enzymes and mitochondria. ku ku ku ku
6. Injured cells have impaired flow of substances through the cell membrane as a result of:
ku ku ku ku ku ku ku ku ku ku ku ku ku ku
A) increased fat load. ku ku
B) altered permeability. ku
C) altered glucose utilization. ku ku
D) increased surface receptors. ku ku
7. Reversible adaptive intracellular responses are initiated by:
ku ku ku ku ku ku
A) stimulus overload. ku
B) genetic mutations. ku
C) chemical messengers. ku
D) mitochondrial DNA. ku
8. Injured cells become very swollen as a result of:
ku ku ku ku ku ku ku ku
A) increased cell protein synthesis. ku ku ku
B) altered cell volume regulation.
ku ku ku
C) passive entry of potassium into the cell.
ku ku ku ku ku ku
D) bleb formation in the plasma membrane.
ku ku ku ku ku
A diabetic patient has impaired sensation, circulation, and oxygenation of his feet. He
ku ku ku ku ku ku ku ku ku ku ku ku
steps on a piece of glass, the wound does not heal, and the area tissue becomes
ku ku ku ku ku ku ku ku ku ku ku ku ku ku ku ku
9. necrotic. The necrotic cell death is characterized by:
ku ku ku ku ku ku ku ku
A) rapid apoptosis. ku
B) cellular rupture. ku
C) shrinkage and collapse. ku ku
D) chronic inflammation. ku
A 99-year-old woman has experienced the decline of cell function associated with age. A
ku ku ku ku ku ku ku ku ku ku ku ku ku
10. group of theories of cellular aging focus on programmed:
ku ku ku ku ku ku ku ku ku
A) changes with genetic influences. ku ku ku
B) elimination of cell receptor sites. ku ku ku ku
C) insufficient telomerase enzyme. ku ku
D) DNA mutation or faulty repair.
ku ku ku ku
An 89-year-old female patient has experienced significant decreases in her mobility and
ku ku ku ku ku ku ku ku ku ku ku
stamina during a 3-week hospital stay for the treatment of a femoral head fracture.
ku ku ku ku ku ku ku ku ku ku ku ku ku ku
Which of the following phenomena most likely accounts for the patients decrease in
ku ku ku ku ku ku ku ku ku ku ku ku ku
11. muscle function that underlies her reduced mobility?
ku ku ku ku ku ku ku
A) Impaired muscle cell metabolism resulting from metaplasia
ku ku ku ku ku ku
