QIHC-Diagnostic Antibodies for IHC
with verified answers passed
AACT - ANS ✔alpha-1-antichymotrypsin.
Labels the cytoplasm of histiocytes and neoplasms of histiocytic origin, as well as monocytes
and macrophages of human colon, tonsil and skin.
ALK-1 (for heme cases) - ANS ✔The ALK1 (ALK1 cline) antibody labels normal human ALK
protein and the NPM-ALK chimeric protein,
identification of the subgroup of anaplastic large-cell lymphomas (ALCL) that are ALK positive.
Actin in Muscles - ANS ✔For identification of soft tissue tumors with muscle
differentiation
Stains: C
Diag: leiomyoma, leiomyosarcoma (smooth muscle cancer) and rhabdomyosarcoma
Control: Appendix, colon, tongue
no staining in epithelial cells
CA-125 - ANS ✔For identification of serous ovarian and mesothelioma
Stains: M/C
Control: Fallopian tube
Beta-Catenin - ANS ✔For identification of desmoid tumors, colorectal cancer and colon
adenoma
Stains: Membrane, C/N
Control: Appendix, Colon
, CD4 - ANS ✔Identification of thymocytes, T-helper cells and related tumors such as peripheral T-
cell lymphoma (unspecified), anaplastic large cell lymphoma and mycosis fungoides.
Stains: M/C
control: Tonsil, Liver
CD5 - ANS ✔identification of B-and T-cell malignancies including B-cell chronic lymphoid
leukemia/ small lymphocytic lymphoma, mantle cell lymphoma and T-cell lymphoma and
leukemia
Stains: M/C Control: Tonsil
CD8 - ANS ✔For identification of cytotoxic/suppressor T cells and their neoplastic counterparts
Stains: M/C
Control: tonsil, spleen
CD20 - ANS ✔identification of the B-cell lineage and different types of B-cell lymphoma or
Gastrointestinal lymphoma
Stains: M. Control: Tonsil
CD45 - ANS ✔Leukocyte common antigen (LCA)
identification of tumors of lymphoid origin
Stains: Membrane
Control: tonsil, Brain, Bone Marrow
CD57 - ANS ✔identification of Hodgkin lymphoma (lymphocyte-predominant subtype)T-cell
large granular lymphocyte disorder, oligodendroglioma and neuroendocrine tumor.
Stains M/C
Control: tonsil, Appendix
with verified answers passed
AACT - ANS ✔alpha-1-antichymotrypsin.
Labels the cytoplasm of histiocytes and neoplasms of histiocytic origin, as well as monocytes
and macrophages of human colon, tonsil and skin.
ALK-1 (for heme cases) - ANS ✔The ALK1 (ALK1 cline) antibody labels normal human ALK
protein and the NPM-ALK chimeric protein,
identification of the subgroup of anaplastic large-cell lymphomas (ALCL) that are ALK positive.
Actin in Muscles - ANS ✔For identification of soft tissue tumors with muscle
differentiation
Stains: C
Diag: leiomyoma, leiomyosarcoma (smooth muscle cancer) and rhabdomyosarcoma
Control: Appendix, colon, tongue
no staining in epithelial cells
CA-125 - ANS ✔For identification of serous ovarian and mesothelioma
Stains: M/C
Control: Fallopian tube
Beta-Catenin - ANS ✔For identification of desmoid tumors, colorectal cancer and colon
adenoma
Stains: Membrane, C/N
Control: Appendix, Colon
, CD4 - ANS ✔Identification of thymocytes, T-helper cells and related tumors such as peripheral T-
cell lymphoma (unspecified), anaplastic large cell lymphoma and mycosis fungoides.
Stains: M/C
control: Tonsil, Liver
CD5 - ANS ✔identification of B-and T-cell malignancies including B-cell chronic lymphoid
leukemia/ small lymphocytic lymphoma, mantle cell lymphoma and T-cell lymphoma and
leukemia
Stains: M/C Control: Tonsil
CD8 - ANS ✔For identification of cytotoxic/suppressor T cells and their neoplastic counterparts
Stains: M/C
Control: tonsil, spleen
CD20 - ANS ✔identification of the B-cell lineage and different types of B-cell lymphoma or
Gastrointestinal lymphoma
Stains: M. Control: Tonsil
CD45 - ANS ✔Leukocyte common antigen (LCA)
identification of tumors of lymphoid origin
Stains: Membrane
Control: tonsil, Brain, Bone Marrow
CD57 - ANS ✔identification of Hodgkin lymphoma (lymphocyte-predominant subtype)T-cell
large granular lymphocyte disorder, oligodendroglioma and neuroendocrine tumor.
Stains M/C
Control: tonsil, Appendix
