Test Bank
For Pathophysiology | The
Biologic Basis for Disease
in Adults and Children
8th Edition | Latest
Version 2024
,Chapter j71 j7- j7 Cellular j7Biology_______________________________________ 3
Chapter j72 j7- j7Altered j7Cellular j7and j7Tissue j7Biology j 7 Environmental j7Agents ___ 16
Chapter j73 j7- j7The j7Cellular j7Environment j7Fluids j7and j7Electrolytes j7Acids j 7 and
Bases _________________________________________________________ 28
Chapter j74 j7- j7Genes j7and j 7 Genetic j7Diseases___________________________ 41
Chapter j75 j7- j7Genes j7Environment-Lifestyle j7and j 7 Common j7Diseases _______ 51
Chapter j76 j7- j7Epigenetics j 7 and j7Disease _______________________________ 59
Chapter j77 j7- j7Innate j 7 Immunity j7Inflammation ___________________________ 64
Chapter j78 j7- j 7 Adaptive j7Immunity ____________________________________ 78
Chapter j79 j7- j7Alterations j7in j7Immunity j7 and j7Inflammation _________________ 89
Chapter j710 j7- j7Infection ____________________________________________ 102
Chapter j711 j7- j7Stress j 7 and j7Disease __________________________________ 110
Chapter j712 j7- j7 Cancer j7Biology ______________________________________ 117
Chapter j713 j7- j 7 Cancer j7Epidemiology _________________________________ 129
Chapter j714 j7- j7Cancer j 7 in j7Children ___________________________________ 135
Chapter j715 j7- j7Structure j7and j7Function j7of j7the j 7 Neurologic j7System _________ 140
Chapter j 7 16 j 7 - j 7 Pain j 7 Temperature j 7 Regulation j 7 Sleep j 7 and j 7 Sensory
j 7 Function j 7 151 j7Chapter j717 j7- j7Alterations j7in j7Cognitive j7Systems j7Cerebral
j7 Hemodynamics j 7 and
Motor j7Function __________________________________________________ 165
Chapter j718 j7- j7Disorders j7of j7the j7Central j7and j7Peripheral j7Nervous j7Systems j 7 and
the j7Neuromuscular j7Junction _______________________________________ 179
Chapter j719 j7- j7Neurobiology j7of j7Schizophrenia j7Mood j7Disorders j7and j7Anxiety
j7 Disorders ______________________________________________________ 189
Chapter j720 j7- j7Alterations j7of j7Neurologic j7Function j7 in j7Children ____________ 195
Chapter j721 j7- j7Mechanisms j7of j 7 Hormonal j7Regulation____________________ 202
Chapter j722 j7- j7Alterations j7of j 7 Hormonal j7Regulation _____________________ 211
Chapter j723 j7- j7Obesity j7and j7Disorders j7of j 7 Nutrition j7NEW _________________ 223
Chapter j724 j7- j7Structure j7and j7Function j7of j7the j 7 Reproductive j7Systems ______ 228
Chapter j725 j7- j7Alterations j7of j7the j7Female j 7 Reproductive j7System ___________ 237
,Chapter j726 j7- j7Alterations j7of j7the j7Male j 7 Reproductive j7System _____________ 246
Chapter j727 j7- j7Sexually j 7 Transmitted j7Infections _________________________ 252
Chapter j728 j7- j7Structure j7and j7Function j7of j7the j 7 Hematologic j7System________ 260
Chapter j729 j7- j7Alterations j7of j7Erythrocyte j7Platelet j7and j 7 Hemostatic j7Function _ 270
Chapter j730 j7- j7Alterations j7of j7Leukocyte j7and j 7 Lymphoid j7Function __________ 280
Chapter j731 j7- j7Alterations j7of j7Hematologic j7Function j 7 in j7Children ___________ 287
Chapter j732 j7- j7Structure j7and j7Function j7of j7the j7Cardiovascular j7and j7Lymphatic
j7 Systems ______________________________________________________ 297
Chapter j733 j7- j7Alterations j7of j 7 Cardiovascular j7Function ___________________ 309
Chapter j734 j7- j7Alterations j7of j7Cardiovascular j7Function j7 in j7Children _________ 323
Chapter j735 j7- j7Structure j7and j7Function j7of j7the j 7 Pulmonary j7System _________ 331
Chapter j736 j7- j7Alterations j7of j 7 Pulmonary j7Function ______________________ 341
Chapter j737 j7- j7Alterations j7of j7Pulmonary j7Function j 7 in j7Children ____________ 357
Chapter j738 j7- j7Structure j7and j7Function j7of j7the j7Renal j7and j 7 Urologic j7Systems_ 365
Chapter j739 j7- j7Alterations j7of j7Renal j7and j7 Urinary j7Function _______________ 375
Chapter j740 j7- j7Alterations j7of j7Renal j7and j7Urinary j7Tract j7Function j 7 in j7Children 385
Chapter j741 j7- j7Structure j7and j7Function j7of j7the j 7 Digestive j7System __________ 393
Chapter j742 j7- j7Alterations j7of j 7 Digestive j7Function _______________________ 404
Chapter j743 j7- j7Alterations j7of j7Digestive j7Function j7 in j7Children _____________ 415
Chapter j744 j7- j7Structure j7and j7Function j7of j7the j 7 Musculoskeletal j7System _____ 424
Chapter j745 j7- j7Alterations j7of j 7 Musculoskeletal j7Function __________________ 436
Chapter j746 j7- j7Alterations j7of j7Musculoskeletal j7Function j 7 in j7Children ________ 448
Chapter j747 j7- j7Structure j7Function j7and j7Disorders j7of j 7 the j7Integument _______ 457
Chapter j748 j7- j7Alterations j7of j7the j7Integument j7 in j7Children ________________ 468
Chapter j749 j7- j7Shock j7Multiple j7Organ j7Dysfunction j7Syndrome j7and j7Burns j 7 in
Adults _________________________________________________________ 476
Chapter j750 j7- j7Shock j7Multiple j7Organ j7Dysfunction j7Syndrome j7and j7Burns j 7 in
Children ________________________________________________________ 483
, Chapter j701: j7Cellular j7Biology
McCance/Huether: j7Pathophysiology: j7The j7Biologic j7Basis j7of j7Disease j7in j7Adults
j7and j7Children, j78th j7Edition
MULTIPLE j7CHOICE
1. Which j7statement j7best j7describes j7the j7cellular j7function j7of j7metabolic j7absorption?
a. Cells j7can j7produce j7proteins.
b. Cells j7can j7secrete j7digestive j7enzymes.
c. Cells j7can j7take j7in j7and j7use j7nutrients.
d. Cells j7can j7synthesize j7fats.
ANS: j7 C
In j7metabolic j7absorption, j7all j7cells j7take j7in j7and j7use j7nutrients j7and j7other j7substances
j7from j7their j7surroundings. j7The j7remaining j7options j7are j7not j7inclusive j7in j7their
j7descriptions j7of j7cellular j7metabolic j7absorption.
PTS: j7 j7 1 DIF: Cognitive j7Level: j7Remembering
2. Where j7is j7most j7of j7a j7cell’s j7genetic j7information, j7including j7RNA j7and j7DNA, j7contained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: j7 C
The j7nucleus j7contains j7the j7nucleolus, j7a j7small j7dense j7structure j7composed j7largely j7of j7RNA,
j7most j7of j7the j7cellular j7DNA, j7and j7the j7DNA-binding j7proteins, j7such j7as j7the j7histones,
j7which j7regulate j7its j7activity. j7The j7mitochondria j7are j7responsible j7for j7cellular j7respiration
j7and j7energy j7production.
Ribosomes’ j7chief j7function j7is j7to j7provide j7sites j7for j7cellular j7protein j7synthesis.
j7Lysosomes j7function j7as j7the j7intracellular j7digestive j7system.
PTS: j7 j7 1 DIF: Cognitive j7Level: j7Remembering
3. Which j7component j7of j7the j7cell j7produces j7hydrogen j7peroxide j7(H2O2) j7by j7using j7oxygen j7to
remove j7hydrogen j7atoms j7from j7specific j7substrates j7in j7an j7oxidative j7reaction?
j7
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS: j7 B
For Pathophysiology | The
Biologic Basis for Disease
in Adults and Children
8th Edition | Latest
Version 2024
,Chapter j71 j7- j7 Cellular j7Biology_______________________________________ 3
Chapter j72 j7- j7Altered j7Cellular j7and j7Tissue j7Biology j 7 Environmental j7Agents ___ 16
Chapter j73 j7- j7The j7Cellular j7Environment j7Fluids j7and j7Electrolytes j7Acids j 7 and
Bases _________________________________________________________ 28
Chapter j74 j7- j7Genes j7and j 7 Genetic j7Diseases___________________________ 41
Chapter j75 j7- j7Genes j7Environment-Lifestyle j7and j 7 Common j7Diseases _______ 51
Chapter j76 j7- j7Epigenetics j 7 and j7Disease _______________________________ 59
Chapter j77 j7- j7Innate j 7 Immunity j7Inflammation ___________________________ 64
Chapter j78 j7- j 7 Adaptive j7Immunity ____________________________________ 78
Chapter j79 j7- j7Alterations j7in j7Immunity j7 and j7Inflammation _________________ 89
Chapter j710 j7- j7Infection ____________________________________________ 102
Chapter j711 j7- j7Stress j 7 and j7Disease __________________________________ 110
Chapter j712 j7- j7 Cancer j7Biology ______________________________________ 117
Chapter j713 j7- j 7 Cancer j7Epidemiology _________________________________ 129
Chapter j714 j7- j7Cancer j 7 in j7Children ___________________________________ 135
Chapter j715 j7- j7Structure j7and j7Function j7of j7the j 7 Neurologic j7System _________ 140
Chapter j 7 16 j 7 - j 7 Pain j 7 Temperature j 7 Regulation j 7 Sleep j 7 and j 7 Sensory
j 7 Function j 7 151 j7Chapter j717 j7- j7Alterations j7in j7Cognitive j7Systems j7Cerebral
j7 Hemodynamics j 7 and
Motor j7Function __________________________________________________ 165
Chapter j718 j7- j7Disorders j7of j7the j7Central j7and j7Peripheral j7Nervous j7Systems j 7 and
the j7Neuromuscular j7Junction _______________________________________ 179
Chapter j719 j7- j7Neurobiology j7of j7Schizophrenia j7Mood j7Disorders j7and j7Anxiety
j7 Disorders ______________________________________________________ 189
Chapter j720 j7- j7Alterations j7of j7Neurologic j7Function j7 in j7Children ____________ 195
Chapter j721 j7- j7Mechanisms j7of j 7 Hormonal j7Regulation____________________ 202
Chapter j722 j7- j7Alterations j7of j 7 Hormonal j7Regulation _____________________ 211
Chapter j723 j7- j7Obesity j7and j7Disorders j7of j 7 Nutrition j7NEW _________________ 223
Chapter j724 j7- j7Structure j7and j7Function j7of j7the j 7 Reproductive j7Systems ______ 228
Chapter j725 j7- j7Alterations j7of j7the j7Female j 7 Reproductive j7System ___________ 237
,Chapter j726 j7- j7Alterations j7of j7the j7Male j 7 Reproductive j7System _____________ 246
Chapter j727 j7- j7Sexually j 7 Transmitted j7Infections _________________________ 252
Chapter j728 j7- j7Structure j7and j7Function j7of j7the j 7 Hematologic j7System________ 260
Chapter j729 j7- j7Alterations j7of j7Erythrocyte j7Platelet j7and j 7 Hemostatic j7Function _ 270
Chapter j730 j7- j7Alterations j7of j7Leukocyte j7and j 7 Lymphoid j7Function __________ 280
Chapter j731 j7- j7Alterations j7of j7Hematologic j7Function j 7 in j7Children ___________ 287
Chapter j732 j7- j7Structure j7and j7Function j7of j7the j7Cardiovascular j7and j7Lymphatic
j7 Systems ______________________________________________________ 297
Chapter j733 j7- j7Alterations j7of j 7 Cardiovascular j7Function ___________________ 309
Chapter j734 j7- j7Alterations j7of j7Cardiovascular j7Function j7 in j7Children _________ 323
Chapter j735 j7- j7Structure j7and j7Function j7of j7the j 7 Pulmonary j7System _________ 331
Chapter j736 j7- j7Alterations j7of j 7 Pulmonary j7Function ______________________ 341
Chapter j737 j7- j7Alterations j7of j7Pulmonary j7Function j 7 in j7Children ____________ 357
Chapter j738 j7- j7Structure j7and j7Function j7of j7the j7Renal j7and j 7 Urologic j7Systems_ 365
Chapter j739 j7- j7Alterations j7of j7Renal j7and j7 Urinary j7Function _______________ 375
Chapter j740 j7- j7Alterations j7of j7Renal j7and j7Urinary j7Tract j7Function j 7 in j7Children 385
Chapter j741 j7- j7Structure j7and j7Function j7of j7the j 7 Digestive j7System __________ 393
Chapter j742 j7- j7Alterations j7of j 7 Digestive j7Function _______________________ 404
Chapter j743 j7- j7Alterations j7of j7Digestive j7Function j7 in j7Children _____________ 415
Chapter j744 j7- j7Structure j7and j7Function j7of j7the j 7 Musculoskeletal j7System _____ 424
Chapter j745 j7- j7Alterations j7of j 7 Musculoskeletal j7Function __________________ 436
Chapter j746 j7- j7Alterations j7of j7Musculoskeletal j7Function j 7 in j7Children ________ 448
Chapter j747 j7- j7Structure j7Function j7and j7Disorders j7of j 7 the j7Integument _______ 457
Chapter j748 j7- j7Alterations j7of j7the j7Integument j7 in j7Children ________________ 468
Chapter j749 j7- j7Shock j7Multiple j7Organ j7Dysfunction j7Syndrome j7and j7Burns j 7 in
Adults _________________________________________________________ 476
Chapter j750 j7- j7Shock j7Multiple j7Organ j7Dysfunction j7Syndrome j7and j7Burns j 7 in
Children ________________________________________________________ 483
, Chapter j701: j7Cellular j7Biology
McCance/Huether: j7Pathophysiology: j7The j7Biologic j7Basis j7of j7Disease j7in j7Adults
j7and j7Children, j78th j7Edition
MULTIPLE j7CHOICE
1. Which j7statement j7best j7describes j7the j7cellular j7function j7of j7metabolic j7absorption?
a. Cells j7can j7produce j7proteins.
b. Cells j7can j7secrete j7digestive j7enzymes.
c. Cells j7can j7take j7in j7and j7use j7nutrients.
d. Cells j7can j7synthesize j7fats.
ANS: j7 C
In j7metabolic j7absorption, j7all j7cells j7take j7in j7and j7use j7nutrients j7and j7other j7substances
j7from j7their j7surroundings. j7The j7remaining j7options j7are j7not j7inclusive j7in j7their
j7descriptions j7of j7cellular j7metabolic j7absorption.
PTS: j7 j7 1 DIF: Cognitive j7Level: j7Remembering
2. Where j7is j7most j7of j7a j7cell’s j7genetic j7information, j7including j7RNA j7and j7DNA, j7contained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: j7 C
The j7nucleus j7contains j7the j7nucleolus, j7a j7small j7dense j7structure j7composed j7largely j7of j7RNA,
j7most j7of j7the j7cellular j7DNA, j7and j7the j7DNA-binding j7proteins, j7such j7as j7the j7histones,
j7which j7regulate j7its j7activity. j7The j7mitochondria j7are j7responsible j7for j7cellular j7respiration
j7and j7energy j7production.
Ribosomes’ j7chief j7function j7is j7to j7provide j7sites j7for j7cellular j7protein j7synthesis.
j7Lysosomes j7function j7as j7the j7intracellular j7digestive j7system.
PTS: j7 j7 1 DIF: Cognitive j7Level: j7Remembering
3. Which j7component j7of j7the j7cell j7produces j7hydrogen j7peroxide j7(H2O2) j7by j7using j7oxygen j7to
remove j7hydrogen j7atoms j7from j7specific j7substrates j7in j7an j7oxidative j7reaction?
j7
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS: j7 B
