Preparation Reactions
Amines 1) Rxnoghalogenoalkanesw / ammonia
3) prep of aromatic
☆ nitroaienereducedusinqmixottintconc.tk/heatedrelMX 1) llhanoularion
excels till neutratillddttlr
amides
☆ Ntlzwlacul Chlorides
→
↳ aliphatic warming haw / excess NH } ☆
-
ethanol solvent / lthanoliltol WINH } ) j
ftp.NFVA /
+ .
smconc
""
☆ ( H }CHz( It NH > ( een ) → ( Hzlth Nth 1- HCl No , + 6[ H ] s Nth 1-11-40 HI -
C Nit , → the
peg ,u× 5 '
CI
☆ derivates of ammonia , /ormore H atoms 1- Chlorethane ethyl amine g- ernan
replaced by (Hgroup H nitrobenzene Phenkllamine ethanoul Chloride
H
p it ,H
I
1st g-
Primary : only one ( chain attached to N H C -
-
C
✗
Cl H C C
- - -
N
'
Steph .
I, I
°
H
'
' "
1
I
☆ amine
,
Secondary :N atom attached to 2C atoms
HH ☆ benzene wlnitrarinqmixar tempt/ 55°C wlaiuichloride → sub
j,,
Hill "
Tertiary :N atom attached to 3C chains ☆ nitrating mix
=
lone . HNO > + conc _
, , , .nu ,
µ, , ,
, + (µ, →
47 Nucleophilic substitution Zthsout HNO > NOT Hit +211104
-
→ + ,
ethyl amine
"
Y
'
Ntlutcl
Properties 47 NH , + HCl → Hyun
↓ - -
-
-
Noi → 1- Ht 4> important for identifying amine
→
☆ bpt Aw / molecular mats ☆ product lthulamine , ,
lone pair on N : . attack ↑ vdw 's → ↑ mpt →
subam
↳ ↑ bphthanlorrel Pending alkane →
Hbondg Chloro ethane 4> reirusraliitarion : mph determine
☆ * mass compounds soluble in tho 14 bonds / ☆ IHzctlilltctlzctkNI-k-lltlr.lt/ilzNHtHClSteP2 :
mpt data
"
4> ↓ alkyl chain ↑ length ☆ nitrobenzene red but produced insirubusnt
"
as H ' cone HCl
↑ gig
- .
.
,
,
g. µ
, ' '
↳ organic ri - in water bath for 30m red N°210 NHL
☆ mix refluxed
,
soluble in solvents
✗
H C C Cl " a :
-
-
H C C
- -
- - -
◦
1 In a "
hit
Aliphatic NO ,
H H "
" ""
SMH
H-HHIN.it
'
colourless liquids
' diethulamine
+ f[ H]
+211,0
☆ pungent fishy , smelling ,
☆ tbpt than comparable alcohol/ AIN Hill
-
↳ minimise further sub + prepare only Pamina →
Volatile
polarised More excess of NH} ☆ for tulleq 6[ H] 3Sn+6HC1 product 35inch
' '
-_
.
.
. : → . .
Aromatic
☆ lower members = oily sweet smelling , toxic
,
'
2) Red .
or nitrites ☆ in acidic conditions otrxn flask , amine sainfoins
Reactions of be
liquids ( H > IN ↳ [ H]
"" "
%'lH}CHzNH2 + 1) w / Hit / On warmin
+ NH, NH > a-
"
☆ higher members =
trutta / line solids
Hy -
[ =.N n
-
1- HCl I ☆ benzene diazonium chloride
µ
-
. .
'
☆ A solubility intro but reasonably volatile 1,1 ,
ti excess
a-
i. Steam distilled ↳ retluxedwllimalinaruether +
NIN 1-
☆ liberated by excess NaOH pellets
Basicity Relative Base Strengths
Ntlstcl Colts Nzcl
-
/
Ntlz
1- NaOH → 1- NaCl 1- tho
☆ weak bases : lone pair or e- ONN .
: ☆ strength depends onavailabilituot tone 2) WIKI solution
accept proton / Ht video ord bonds Nt ability to accept Ht ☆ Steam distilled phenylamine vapour carried over bar ☆ reach when warmed wl
pair on
-
,
☆ greater the e- density on N better co
-
ord when condenses , separates from tho cat insoluble )
µ +
,
extracted water
Amines 1) Rxnoghalogenoalkanesw / ammonia
3) prep of aromatic
☆ nitroaienereducedusinqmixottintconc.tk/heatedrelMX 1) llhanoularion
excels till neutratillddttlr
amides
☆ Ntlzwlacul Chlorides
→
↳ aliphatic warming haw / excess NH } ☆
-
ethanol solvent / lthanoliltol WINH } ) j
ftp.NFVA /
+ .
smconc
""
☆ ( H }CHz( It NH > ( een ) → ( Hzlth Nth 1- HCl No , + 6[ H ] s Nth 1-11-40 HI -
C Nit , → the
peg ,u× 5 '
CI
☆ derivates of ammonia , /ormore H atoms 1- Chlorethane ethyl amine g- ernan
replaced by (Hgroup H nitrobenzene Phenkllamine ethanoul Chloride
H
p it ,H
I
1st g-
Primary : only one ( chain attached to N H C -
-
C
✗
Cl H C C
- - -
N
'
Steph .
I, I
°
H
'
' "
1
I
☆ amine
,
Secondary :N atom attached to 2C atoms
HH ☆ benzene wlnitrarinqmixar tempt/ 55°C wlaiuichloride → sub
j,,
Hill "
Tertiary :N atom attached to 3C chains ☆ nitrating mix
=
lone . HNO > + conc _
, , , .nu ,
µ, , ,
, + (µ, →
47 Nucleophilic substitution Zthsout HNO > NOT Hit +211104
-
→ + ,
ethyl amine
"
Y
'
Ntlutcl
Properties 47 NH , + HCl → Hyun
↓ - -
-
-
Noi → 1- Ht 4> important for identifying amine
→
☆ bpt Aw / molecular mats ☆ product lthulamine , ,
lone pair on N : . attack ↑ vdw 's → ↑ mpt →
subam
↳ ↑ bphthanlorrel Pending alkane →
Hbondg Chloro ethane 4> reirusraliitarion : mph determine
☆ * mass compounds soluble in tho 14 bonds / ☆ IHzctlilltctlzctkNI-k-lltlr.lt/ilzNHtHClSteP2 :
mpt data
"
4> ↓ alkyl chain ↑ length ☆ nitrobenzene red but produced insirubusnt
"
as H ' cone HCl
↑ gig
- .
.
,
,
g. µ
, ' '
↳ organic ri - in water bath for 30m red N°210 NHL
☆ mix refluxed
,
soluble in solvents
✗
H C C Cl " a :
-
-
H C C
- -
- - -
◦
1 In a "
hit
Aliphatic NO ,
H H "
" ""
SMH
H-HHIN.it
'
colourless liquids
' diethulamine
+ f[ H]
+211,0
☆ pungent fishy , smelling ,
☆ tbpt than comparable alcohol/ AIN Hill
-
↳ minimise further sub + prepare only Pamina →
Volatile
polarised More excess of NH} ☆ for tulleq 6[ H] 3Sn+6HC1 product 35inch
' '
-_
.
.
. : → . .
Aromatic
☆ lower members = oily sweet smelling , toxic
,
'
2) Red .
or nitrites ☆ in acidic conditions otrxn flask , amine sainfoins
Reactions of be
liquids ( H > IN ↳ [ H]
"" "
%'lH}CHzNH2 + 1) w / Hit / On warmin
+ NH, NH > a-
"
☆ higher members =
trutta / line solids
Hy -
[ =.N n
-
1- HCl I ☆ benzene diazonium chloride
µ
-
. .
'
☆ A solubility intro but reasonably volatile 1,1 ,
ti excess
a-
i. Steam distilled ↳ retluxedwllimalinaruether +
NIN 1-
☆ liberated by excess NaOH pellets
Basicity Relative Base Strengths
Ntlstcl Colts Nzcl
-
/
Ntlz
1- NaOH → 1- NaCl 1- tho
☆ weak bases : lone pair or e- ONN .
: ☆ strength depends onavailabilituot tone 2) WIKI solution
accept proton / Ht video ord bonds Nt ability to accept Ht ☆ Steam distilled phenylamine vapour carried over bar ☆ reach when warmed wl
pair on
-
,
☆ greater the e- density on N better co
-
ord when condenses , separates from tho cat insoluble )
µ +
,
extracted water
